<abstract xmlns="http://www.w3.org/1999/xhtml"><bold><italic>Objectives</italic></bold>. To assess the association between education degree and attitude towards the treatment after myocardial infarction (MI).<bold><italic>Design and Methods</italic></bold>. The participants of this cross-sectional study were 191 (140 men and 51 women) outpatients in a period of 3 months – 5 years after acute MI (mean age 59 ± 9.2 years) from Vilnius University Hospital Santaros Klinikos. All patients were asked to complete two questionnaires: “Quality of Life and Treatment after Myocardial Infarction” and “Cholesterol-lowering Drugs Consumption Peculiarities”. The data was analyzed using the SPSS software.<bold><italic>Results</italic></bold>. The education degree (a higher (post-secondary education provided by a college or university) vs. a lower (secondary or vocational education) education degree) had similar influence on the patients’ occasional concern (43.2%; <italic>n</italic> = 35 vs. 52.9%; <italic>n</italic> = 55, respectively; <italic>p</italic> = 0.226) and on the frequent concern (25.9%; <italic>n</italic> =21 vs. 26.9%; <italic>n</italic> = 28, respectively; <italic>p</italic> = 0.226) about MI. Patients with a higher education degree were more likely to identify themselves as the main subjects in MI treatment in comparison with patients that had a lower education degree (30.5%; <italic>n</italic> = 25 vs. 15.2%; <italic>n</italic> = 16, respectively, <italic>p</italic> = 0.033). More educated patients found it easier to follow up the doctor’s treatment plan than less educated patients (23.2%; <italic>n</italic> = 19 vs. 9.5%; <italic>n</italic> = 10, respectively; <italic>p</italic> = 0.035).<bold><italic>Conclusions</italic></bold>. More educated patients are more likely to follow up the doctor’s treatment plan and see it easier than less educated patients. Thus, more attention should be paid to less educated patients in order to increase their own impact on their post-MI treatment.</abstract>

Vilnius University Hospital Santaros Klinikos

Does education degree affect the patient’s attitude towards the treatment after myocardial infarction?

<abstract xmlns="http://www.w3.org/1999/xhtml"><bold>Objectives:</bold> There is increasing evidence that metabolic syndrome (MetS) may be associated with increased uric acid levels. Previous studies indicate that hyperuricaemia is an independent risk factor for cardiovascular disorders. We sought to determine the association of serum uric acid (SUA) with MetS components and other cardiovascular risk factors among middle aged Lithuanians with MetS.<bold>Design and methods:</bold> A cross-sectional study was conducted in 2018. A total of 705 subjects aged 40 to 65 years with MetS diagnosed using NCEP ATP III criteria were included. None of the participants had previously diagnosed cardiovascular, cerebrovascular, peripheral artery or end-stage oncological disease. Blood tests and all anthropometric measurements were obtained using standard methods. Subjects were divided into 2 groups: with hyperuricaemia and without hyperuricaemia.<bold>Results:</bold> Hyperuricaemia was found in 33.3% of subjects. Mean serum uric acid level increased as the number of metabolic factors increased. Participants with hyperuricaemia had abnormal waist circumference (p &lt; 0.001), higher systolic (p = 0.001) and diastolic blood pressure (p = 0.003), higher levels of triglycerides and, lower levels of high-density lipoprotein cholesterol (p &lt; 0.001). Subjects in hyperuricaemia group were more likely to be alcohol users (p = 0.034), to have diabetes (p = 0.02) and higher body mass index (p &lt; 0.001). Their creatinine levels were statistically significantly higher (p &lt; 0.001).<bold>Conclusions:</bold> Our analysis showed that serum uric acid is associated with MetS and other cardiovascular risk factors. The study found a statistically significant association with the four out of five components of the MetS (excluding plasma glucose) as well as with alcohol consumption, and renal function indicators (creatinine, eGFR).</abstract>

State Research Institute Centre for Innovative Medicine

Clinic of Cardiac and Vascular Diseases, Faculty of Medicine, Institute of Clinical Medicine

Vilnius University Faculty of Mathematics and Informatics

Institute of Data Science and Digital Technologies

Is the increase of uric acid associated with the components of the metabolic syndrome?

<abstract xmlns="http://www.w3.org/1999/xhtml"><bold>Objectives</bold>: Circulating levels of inflammatory markers such as high sensitivity C-reactive protein (hs-CRP) have been reported to be associated with increased risk of cardiovascular disease (CVD), as well as with metabolic syndrome (MetS). Therefore, our objectives were to investigate the associations between hs-CRP levels and individual MetS components as well as to analyse if hs-CRP levels are linked with the number of MetS components present in middle-aged subjects.<bold>Design and methods</bold>: A cross-sectional study included 4628 middle-aged MetS subjects from the Lithuanian High Cardiovascular Risk primary prevention programme (LitHiR) from 2011 to 2020. MetS was diagnosed according to the National Cholesterol Education Program ATP III modified criteria. CRP was measured by a validated high-sensitivity assay. A hs-CRP cutpoint of 5 mg/l was used to differentiate high and low hs-CRP groups.<bold>Results</bold>: The mean value of hs-CRP was 3.23 ± 4.04 mg/l, and significantly increased as the number of components of MetS increased (<italic>p</italic> &lt; 0.001). The concentration of serum hs-CRP was significantly associated with waist circumference, systolic and diastolic blood pressure, and fasting blood glucose (all <italic>p</italic> &lt; 0.001). However, no statistically significant associations were found between hs-CRP and serum triglycerides (<italic>p</italic> = 0.340) or serum high-density lipoprotein cholesterol (<italic>p</italic> = 0.148).<bold>Conclusions</bold>: Serum hs-CRP increased progressively with increased waist circumference, blood pressure, fasting blood glucose in middle-aged subjects with MetS. The higher values of hs-CRP were more often present in obese subjects and women. The incremental rise in mean serum hs-CRP level was found with an increasing number of MetS components.</abstract>

Association of high sensitivity C-reactive protein and metabolic syndrome components in middle-aged subjects without overt cardiovascular disease in LitHiR primary prevention programme

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Seminars in Cardiovascular Medicine

Volume 26 (2020): Issue 1 (January 2020)

Does education degree affect the patient’s attitude towards the treatment after myocardial infarction?

Is the increase of uric acid associated with the components of the metabolic syndrome?

Association of high sensitivity C-reactive protein and metabolic syndrome components in middle-aged subjects without overt cardiovascular disease in LitHiR primary prevention programme

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