<abstract xmlns="http://www.w3.org/1999/xhtml">

<p>Among 140 patients colonized by KPC-producing <italic>Klebsiella pneumoniae</italic> (KPC-Kp) between fourth and seventh day of Intensive Care Unit stay, 24 developed bacteraemia immediately after colonization. Colistin-resistance of the colonizing isolate was the factor significantly associated with early KPC-Kp bacteraemia (<italic>P</italic> &lt; 0.001; OR 6.6, 95% CI 2.4–18.4), a worrisome finding since infections by colistin-resistant isolates is associated with increased mortality due to limited remaining therapeutic options.</p>
</abstract>

Among 140 patients colonized by KPC-producing Klebsiella pneumoniae (KPC-Kp) between fourth and seventh day of Intensive Care Unit stay, 24 developed bacteraemia immediately after colonization. Colistin-resistance of the colonizing isolate was the factor significantly associated with early KPC-Kp bacteraemia (P < 0.001; OR 6.6, 95% CI 2.4–18.4), a worrisome finding since infections by colistin-resistant isolates is associated with increased mortality due to limited remaining therapeutic options.

Early KPC-Producing <italic>Klebsiella pneumoniae</italic> Bacteremia among Intensive Care Unit Patients Non-Colonized upon Admission

Saint Andrew’s General Hospital of Patras

Polish Journal of Microbiology

This work is licensed under the Creative Commons Attribution-NonCommercial-NoDerivatives 4.0 International License.

Early KPC-Producing  Bacteremia among Intensive Care Unit Patients Non-Colonized upon Admission

Among 140 patients colonized by KPC-producing Klebsiella pneumoniae (KPC-Kp) between fourth and seventh day of Intensive Care Unit stay, 24 developed...

Early KPC-Producing Klebsiella pneumoniae Bacteremia among Intensive Care Unit Patients Non-Colonized upon Admission

Pubblicato online: 28 giu 2017

Pagine: 251 - 254

Ricevuto: 05 set 2016

Accettato: 12 gen 2017

DOI: https://doi.org/10.5604/pjm-2017-251

Parole chiave
bacteremia, carbapenemase, colistin-resistance, critically ill patients

© 2017 MATTHAIOS PAPADIMITRIOU-OLIVGERIS et al., published by Sciendo

This work is licensed under the Creative Commons Attribution-NonCommercial-NoDerivatives 4.0 International License.

Early KPC-Producing Klebsiella pneumoniae Bacteremia among Intensive Care Unit Patients Non-Colonized upon Admission

Pubblicato online: 28 giu 2017

Pagine: 251 - 254

Ricevuto: 05 set 2016

Accettato: 12 gen 2017

DOI: https://doi.org/10.5604/pjm-2017-251

Parole chiavebacteremia, carbapenemase, colistin-resistance, critically ill patients

© 2017 MATTHAIOS PAPADIMITRIOU-OLIVGERIS et al., published by Sciendo

This work is licensed under the Creative Commons Attribution-NonCommercial-NoDerivatives 4.0 International License.

Parole chiave
bacteremia, carbapenemase, colistin-resistance, critically ill patients