Immunotherapeutic efficacy of a Lactobacillus casei lysate as an adjuvant combined with a heated-4T1 mammary carcinoma cell lysate in a murine model of breast cancer
This work is licensed under the Creative Commons Attribution-NonCommercial-NoDerivatives 3.0 License.
Figure 1
Comparison of lung weight (upper left), tumor necrosis factor (TNF)-α levels (upper right), tumor size (lower left), and tumor weight (lower right), and after immunization with a heated-4T1-cell lysate alone (hatched bar), the L. casei lysate alone (open bar), and their combination (crosshatchedbar). *P < 0.05, **P < 0.01, ***P < 0.001, and ****P< 0.0001.
Figure 2
Levels of IL-2 (upper left), IL-12 (upper right), IL-13 (lower left), and IL-17 (lower right) after immunization with a heated-4T1-cell lysate alone (hatched bar), the L. casei lysate alone (open bar), and their combination (crosshatchedbar). *P < 0.05, **P < 0.01, ***P < 0.001, and ****P < 0.0001.