Accesso libero

Original article. Transcription factors regulate Forkhead box O1 gene promoter activity in pancreatic β-cells

INFORMAZIONI SU QUESTO ARTICOLO

Cita

1. Kitamura T, Nakae J, Kitamura Y, Kido Y, Biggs WH 3rd, Wright CV, et al. The forkhead transcription factor Foxo1 links insulin signaling to Pdx1 regulation of pancreatic beta cell growth. J Clin Invest. 2002; 110: 1839-47.10.1172/JCI200216857Search in Google Scholar

2. Sussel L, Kalamaras J, Hartigan OCDJ, Meneses JJ, Pedersen RA, Rubenstein JL, et al. Mice lacking the homeodomain transcription factor Nkx2.2 have diabetes due to arrested differentiation of pancreatic beta cells. Development. 1998; 125:2213-21.10.1242/dev.125.12.2213Search in Google Scholar

3. Sander M, Sussel L, Conners J, Scheel D, Kalamaras J, Dela Cruz F, et al. Homeobox gene Nkx6.1 lies downstream of Nkx2.2 in the major pathway of betacell formation in the pancreas. Development. 2000; 127: 5533-40.10.1242/dev.127.24.5533Search in Google Scholar

4. Wang J, Elghazi L, Parker SE, Kizilocak H, Asano M, Sussel L, et al. The concerted activities of Pax4 and Nkx2.2 are essential to initiate pancreatic beta-cell differentiation. Dev Biol. 2004; 266:178-89.10.1016/j.ydbio.2003.10.018Search in Google Scholar

5. Kawamori D, Kaneto H, Nakatani Y, Matsuoka TA, Matsuhisa M, Hori M, et al. The forkhead transcription factor Foxo1 bridges the JNK pathway and the transcription factor PDX-1 through its intracellular translocation. J Biol Chem. 2006; 281:1091-8.10.1074/jbc.M508510200Search in Google Scholar

6. Hennige AM, Ozcan U, Okada T, Jhala US, Schubert M, White MF, et al. Alterations in growth and apoptosis of insulin receptor substrate-1-deficient beta-cells. Am J Physiol Endocrinol Metab. 2005; 289:E337-46.10.1152/ajpendo.00032.2004Search in Google Scholar

7. Wither DJ, Gutierrez JS, Towery H, Burks DJ, Ren JM, Previs S, et al. Disruption of IRS-2 causes type 2 diabetes in mice. Nature. 1998; 391:900-4.10.1038/36116Search in Google Scholar

8. Kulkarni RN, Bruning JC, Winnay JN, Postic C, Magnuson MA, Kahn CR. Tissue-specific knockout of the insulin receptor in pancreatic beta cells creates an insulin secretory defect similar to that in type 2 diabetes. Cell. 1999; 96:329-39.10.1016/S0092-8674(00)80546-2Search in Google Scholar

9. Hennige AM, Burks DJ, Ozcan U, Kulkarni RN, Ye J, Park S, et al. Upregulation of insulin receptor substrate-2 in pancreatic beta cells prevents diabetes. J Clin Invest. 2003; 112:1521-32.10.1172/JCI18581Search in Google Scholar

10. Brunet A, Bonni A, Zigmond MJ, Lin MZ, Juo P, Hu LS, et al. Akt promotes cell survival by phosphorylating and inhibiting a forkhead transcription factor. Cell. 1999; 96:857-68.10.1016/S0092-8674(00)80595-4Search in Google Scholar

11. Zhang XF, Zhang JJ, Yang XM, Han X. Several transcription factors regulate COX-2 gene expression in pancreatic -cells. Mol Biol Rep. 2007; 34: 199-206.10.1007/s11033-007-9085-317505916Search in Google Scholar

12. Impey S, McCorkle SR, Cha-Molstad H, Dwyer JM, Yochum GS. Defining the CREB regulon: a genomewide analysis of transcription factor regulatory regions. Cell. 2004; 119:1041-54.Search in Google Scholar

13. Maiese K, Chong ZZ, Shang YC. OutFOXOing disease and disability: The therapeutic potential of targeting FoxO proteins. Trends Mol Med. 2008; 14:219-27.10.1016/j.molmed.2008.03.002257215018403263Search in Google Scholar

14. Guo S, Rena G, Cichy S, He X, Cohen P, Unterman T. Phosphorylation of serine 256 by protein kinase B disrupts transactivation by FKHR and mediates effects of insulin on insulin-like growth factor-binding protein-1 promoter activity through a conserved insulin response sequence. J Biol Chem. 1999; 274:17184-92.10.1074/jbc.274.24.1718410358076Search in Google Scholar

15. Nakae J, Park BC, Accili D. Insulin stimulates phosphorylation of the forkhead transcription factor FKHR on serine 253 through a Wortmannin-sensitive pathway. J Biol Chem. 1999; 274:15982-5.10.1074/jbc.274.23.1598210347145Search in Google Scholar

16. Kamei Y, Miura S, Suzuki M, Kai Y, Mizukami J, Taniguchi T, et al. Skeletal muscle FOXO1 (FKHR) transgenic mice have less skeletal muscle mass, downregulated Type I (slow twitch/red muscle) fiber genes, and impaired glycemic control. J Biol Chem. 2004; 279: 41114-23.10.1074/jbc.M40067420015272020Search in Google Scholar

17. Zhang X, Yong W, Lv J, Zhu Y, Zhang J, Chen F, et al. Inhibition of forkhead box O1 protects pancreatic betacells against dexamethasone-induced dysfunction. Endocrinology. 2009; 150: 4065-73.10.1210/en.2009-034319443572Search in Google Scholar

18. Cardenas C, Muller M, Jaimovich E. Carrasco Depolarization of skeletal muscle cells induces phosphorylation of cAMP response element binding protein via calcium and protein kinase Calpha. J Biol Chem. 2004; 279:39122-31.10.1074/jbc.M40104420015262987Search in Google Scholar

19. Wu GY, Deisseroth K, Tsien RW. Activity-dependent CREB phosphorylation: convergence of a fast, sensitive calmodulin kinase pathway and a slow, less sensitive mitogen-activated protein kinase pathway. Proc Natl Acad Sci USA. 2001; 98:2808-13.10.1073/pnas.0516341983022111226322Search in Google Scholar

20. Togo T. Long-term potentiation of wound-induced exocytosis and plasma membrane repair is dependent on cAMP-response element-mediated transcription via a protein kinase C- and p38 MAPK-dependent pathway. J Biol Chem. 2004; 279:44996-5003.10.1074/jbc.M40632720015317814Search in Google Scholar

21. Mitsuru O, Dennis JC, Roxana MM, Amilcar FM, Terry GU, Peter R. Signal transducer and activator of transcription (Stat) 5b-mediated inhibition of insulinlike growth factor binding protein-1 gene transcription: a mechanism for repression of gene expression by growth hormone. Mol Endocrinol. 2007; 21: 1443-57.10.1210/me.2006-054317426286Search in Google Scholar

22. Sharrocks AD, Brown AL, Ling Y. The ETS-domain transcription factor family. Int J Biochem Cell Biol. 1997; 29:1371-87.10.1016/S1357-2725(97)00086-1Search in Google Scholar

23. Buchwalter G, Gross C, Wasylyk B. Ets ternary complex transcription factors. Gene. 2004; 324:1-14.10.1016/j.gene.2003.09.02814693367Search in Google Scholar

24. Kasza A, O’Donnell A, Gascoigne K, Zeef LA, Hayes A, Sharrocks AD. The ETS domain transcription factor Elk-1 regulates the expression of its partner protein, SRF. J Biol Chem. 2005; 280:1149-55.10.1074/jbc.M41116120015531578Search in Google Scholar

eISSN:
1875-855X
Lingua:
Inglese
Frequenza di pubblicazione:
6 volte all'anno
Argomenti della rivista:
Medicine, Assistive Professions, Nursing, Basic Medical Science, other, Clinical Medicine