This work is licensed under the Creative Commons Attribution 4.0 International License.
Acsai K, Kun A, Farkas AS, Fülöp F, Nagy N, Balázs M et al. (2007). Effect of partial blockade of the Na+/Ca2+-exchanger on Ca2+ handling in isolated rat ventricular myocytes. Eur J Pharmacol. 576: 1–6.AcsaiKKunAFarkasASFülöpFNagyNBalázsM2007Effect of partial blockade of the Na+/Ca2+-exchanger on Ca2+ handling in isolated rat ventricular myocytes5761610.1016/j.ejphar.2007.07.04717727839Search in Google Scholar
Baba A, Tachi M, Maruyama Y, Kazama I (2015). Suppressive effects of diltiazem and verapamil on delayed rectifier K+-channel currents in murine thymocytes. Pharmacol Rep. 67(5):959–964.BabaATachiMMaruyamaYKazamaI2015Suppressive effects of diltiazem and verapamil on delayed rectifier K+-channel currents in murine thymocytes67595996410.1016/j.pharep.2015.01.00926398391Search in Google Scholar
Baczkó I, Giles WR, Light PE (2003). Resting membrane potential regulates Na+-Ca2+ exchange-mediated Ca2+ -overload during hypoxia-reoxygenation in rat ventricular myocytes. J Physiol Lond. 550: 889–898.BaczkóIGilesWRLightPE2003Resting membrane potential regulates Na+-Ca2+ exchange-mediated Ca2+ -overload during hypoxia-reoxygenation in rat ventricular myocytes55088989810.1113/jphysiol.2003.043372234309212807988Search in Google Scholar
Bers DM (2000). Calcium fluxes involved in control of cardiac myocyte contraction. Circ. Res. 87: 275–281.BersDM2000Calcium fluxes involved in control of cardiac myocyte contraction8727528110.1161/01.RES.87.4.27510948060Search in Google Scholar
Bers DM (2002). Cardiac excitation-contraction coupling. Nature 415: 198–205.BersDM2002Cardiac excitation-contraction coupling41519820510.1016/B978-0-12-378630-2.00221-8Search in Google Scholar
Bers DM (2006). Altered cardiac myocyte Ca regulation in heart failure. Physiology (Bethesda, MD) 21: 380–387.BersDM2006Altered cardiac myocyte Ca regulation in heart failure2138038710.1152/physiol.00019.200617119150Search in Google Scholar
Bers DM (2008). Calcium cycling and signaling in cardiac myocytes. Annu. Rev. Physiol. 70: 23–49.BersDM2008Calcium cycling and signaling in cardiac myocytes70234910.1146/annurev.physiol.70.113006.10045517988210Search in Google Scholar
Bers DM, Ziolo MT (2001). When is cAMP not cAMP? Effects of compartmentalization. Circ Res 89: 373–375.BersDMZioloMT2001When is cAMP not cAMP? Effects of compartmentalization8937337510.1161/res.89.5.373Search in Google Scholar
Birinyi P, Acsai K, Bányász T, Tóth A, Horváth B, Virág L, et al (2005). Effects of SEA0400 and KB-R7943 on Na+/Ca2+ exchange current and L-type Ca2+ current in canine ventricular cardiomyocytes. Naunyn-Schmiedeberg's Arch. Pharmacol. 372: 63–70.BirinyiPAcsaiKBányászTTóthAHorváthBVirágL2005Effects of SEA0400 and KB-R7943 on Na+/Ca2+ exchange current and L-type Ca2+ current in canine ventricular cardiomyocytes372637010.1007/s00210-005-1079-x16086157Search in Google Scholar
Bourgonje VJ, Vos MA, Ozdemir S, Doisne N, Acsai K, Varró A et al. (2013) Combined Na+/Ca2+ exchanger and L-type calcium channel block as a potential strategy to suppress arrhythmias and maintain ventricular function. Circ Arrhythm Electrophysiol. 6:371–379.BourgonjeVJVosMAOzdemirSDoisneNAcsaiKVarróA2013Combined Na+/Ca2+ exchanger and L-type calcium channel block as a potential strategy to suppress arrhythmias and maintain ventricular function637137910.1161/CIRCEP.113.00032223515266Search in Google Scholar
Choi HS, Eisner DA (1995). The role of sarcolemmal Ca2+-ATPase in the regulation of resting calcium concentration in rat ventricular myocytes. J Physiol Lond. 515 (Pt 1): 109–118.ChoiHSEisnerDA1995The role of sarcolemmal Ca2+-ATPase in the regulation of resting calcium concentration in rat ventricular myocytes515Pt 110911810.1111/j.1469-7793.1999.109ad.x22691219925882Search in Google Scholar
Curtis MJ, Hancox JC, Farkas A, Wainwright CL, Stables CL, Saint DA et al (2013). The Lambeth Conventions (II): guidelines for the study of animal and human ventricular and supraventricular arrhythmias. Pharmacol. Therapeut. 139(2): 213–248.CurtisMJHancoxJCFarkasAWainwrightCLStablesCLSaintDA2013The Lambeth Conventions (II): guidelines for the study of animal and human ventricular and supraventricular arrhythmias139221324810.1016/j.pharmthera.2013.04.00823588158Search in Google Scholar
Eurostat Statistics Explained (2018a). Cardiovascular diseases statistics: (http://ec.europa.eu/eurostat/statistics-explained/index.php/Cardiovascular_diseases_statistics#Deaths_from_cardiovascular_diseases)Eurostat Statistics Explained2018a(http://ec.europa.eu/eurostat/statistics-explained/index.php/Cardiovascular_diseases_statistics#Deaths_from_cardiovascular_diseases)Search in Google Scholar
Eurostat Statistics Explained (2018b). Causes of death-standardised death rate: (https://ec.europa.eu/eurostat/statistics-explained/index.php?title=File:Causes_of_death_%E2%80%94_standardised_death_rate,_EU-27,_2016_(per_100_000_inhabitants)_Health 20.png)Eurostat Statistics Explained2018b(https://ec.europa.eu/eurostat/statistics-explained/index.php?title=File:Causes_of_death_%E2%80%94_standardised_death_rate,_EU-27,_2016_(per_100_000_inhabitants)_Health 20.png)Search in Google Scholar
Geramipour A, Kohajda Z, Corici C, Prorok J, Szakonyi Z, Oravecz K et al (2016). The investigation of the cellular electrophysiological and antiarrhythmic effects of a novel selective sodium-calcium exchanger inhibitor, GYKB-6635, in canine and guinea-pig hearts. Can J Physiol Pharmacol. 94(10):1090–1101.GeramipourAKohajdaZCoriciCProrokJSzakonyiZOraveczK2016The investigation of the cellular electrophysiological and antiarrhythmic effects of a novel selective sodium-calcium exchanger inhibitor, GYKB-6635, in canine and guinea-pig hearts94101090110110.1139/cjpp-2015-056627508313Search in Google Scholar
Hardman JG, Limbird LE, Molinoff PB, Ruddonn RW (1996). In Goodman & Gilman's The Pharmacological Basis of Therapeutics, Roden DM: Antiarrhthmic drugs, Chapter 35: 839–871.HardmanJGLimbirdLEMolinoffPBRuddonnRW1996In Goodman & Gilman's The Pharmacological Basis of Therapeutics, Roden DM: Antiarrhthmic drugs35839871Search in Google Scholar
Jost N, Nagy N, Corici C, Kohajda Z, Horváth A, Acsai K, et al (2013). ORM-10103, a novel specific inhibitor of the sodium/calcium exchanger, decreases early and delayed afterdepolarization in the canine heart. Br J Pharmacol. 170: 768–778.JostNNagyNCoriciCKohajdaZHorváthAAcsaiK2013ORM-10103, a novel specific inhibitor of the sodium/calcium exchanger, decreases early and delayed afterdepolarization in the canine heart17076877810.1111/bph.12228379959223647096Search in Google Scholar
Kohajda Z, Farkas-Morvay N, Jost N, Nagy N, Geramipour A, Horváth A et al (2016). The effect of a novel highly selective inhibitor of the sodium/calcium exchanger (NCX) on cardiac arrhythmias in in vitro and in vivoexperiments. PloS One 11: e0166041.KohajdaZFarkas-MorvayNJostNNagyNGeramipourAHorváthA2016The effect of a novel highly selective inhibitor of the sodium/calcium exchanger (NCX) on cardiac arrhythmias in in vitro and in vivoexperiments11e016604110.1371/journal.pone.0166041510440227832106Search in Google Scholar
Missan S, Zhabyeyev P, Dyachok O, Jones SE, McDonald TF (2003). Block of cardiac delayed-rectifier and inward-rectifier K+ currents by nisoldipine. Br J Pharmacol. 140(5):863–870.MissanSZhabyeyevPDyachokOJonesSEMcDonaldTF2003Block of cardiac delayed-rectifier and inward-rectifier K+ currents by nisoldipine140586387010.1038/sj.bjp.0705518157410814530219Search in Google Scholar
Orvos P, Kohajda Z, Szlovák J, Gazdag P, Árpádffy-Lovas T, Tóth D et al (2019). Evaluation of possible proarrhythmic potency: comparison of the effect of dofetilide, cisapride, sotalol, terfenadine and verapamil on hERG and native IKr currents and on cardiac action potential. Toxicol Sci. 168(2):365–380.OrvosPKohajdaZSzlovákJGazdagPÁrpádffy-LovasTTóthD2019Evaluation of possible proarrhythmic potency: comparison of the effect of dofetilide, cisapride, sotalol, terfenadine and verapamil on hERG and native IKr currents and on cardiac action potential168236538010.1093/toxsci/kfy29930561737Search in Google Scholar
Pogwizd SM, Schlotthauer K, Li, L, Yuan W, Bers DM (2001). Arrhythmogenesis and contractile dysfunction in heart failure. Roles of sodium-calcium exchange, inward rectifier potassium current, and residual -adrenergic responsiveness. Circ. Res. 88: 1159–1167.PogwizdSMSchlotthauerKLiLYuanWBersDM2001Arrhythmogenesis and contractile dysfunction in heart failure. Roles of sodium-calcium exchange, inward rectifier potassium current, and residual -adrenergic responsiveness881159116710.1161/hh1101.09119311397782Search in Google Scholar
Skrzypiec-Spring M, Grotthus B, Szeląg A, Schulz R (2007). Isolated heart perfusion according to Langendorff - Still viable in the new millennium. J Pharmacol Toxicol Methods. 55:113–126.Skrzypiec-SpringMGrotthusBSzelągASchulzR2007Isolated heart perfusion according to Langendorff - Still viable in the new millennium5511312610.1016/j.vascn.2006.05.00616844390Search in Google Scholar
Szepesi J, Acsai K, Sebok Z, Prorok J, Pollesello P, Levijoki J et al (2015). Comparison of the efficiency of Na+/Ca2+ exchanger or Na+/H+ exchanger inhibition and their combination in reducing coronary reperfusion-induced arrhythmias. J Physiol Pharmacol. 2015SzepesiJAcsaiKSebokZProrokJPolleselloPLevijokiJ2015Comparison of the efficiency of Na+/Ca2+ exchanger or Na+/H+ exchanger inhibition and their combination in reducing coronary reperfusion-induced arrhythmias2015Search in Google Scholar
Venetucci LA, Trafford AW, O’Neill SC, Eisner DA (2007). Na/Ca exchange: regulator of intracellular calcium and source of arrhythmias in the heart. Ann NY Acad Sci 1099: 315–325.VenetucciLATraffordAWO’NeillSCEisnerDA2007Na/Ca exchange: regulator of intracellular calcium and source of arrhythmias in the heart109931532510.1196/annals.1387.03317446473Search in Google Scholar
Voigt N, Li N, Wang Q, Wang W, Trafford AW, Abu-Taha I et al (2012). Enhanced sarcoplasmic reticulum Ca2+ leak and increased Na+-Ca2+ exchanger function underlie delayed after depolarizations in patients with chronic atrial fibrillation. Circulation 125: 2059–2070.VoigtNLiNWangQWangWTraffordAWAbu-TahaI2012Enhanced sarcoplasmic reticulum Ca2+ leak and increased Na+-Ca2+ exchanger function underlie delayed after depolarizations in patients with chronic atrial fibrillation1252059207010.1161/CIRCULATIONAHA.111.067306Search in Google Scholar
Volders PG, Vos MA, Szabo B, Sipido KR, de Groot SH, Gorgels AP, Wellens HJ, Lazzara R (2000). Progress in the understanding of cardiac early afterdepolarizations and torsades de pointes: time to revise current concepts. Cardiovasc. Res. 46: 376–392.VoldersPGVosMASzaboBSipidoKRde GrootSHGorgelsAPWellensHJLazzaraR2000Progress in the understanding of cardiac early afterdepolarizations and torsades de pointes: time to revise current concepts4637639210.1016/S0008-6363(00)00022-5Search in Google Scholar
Walker MJ, Curtis MJ, Hearse DJ, Campbell RW, Janse MJ, Yellon DM, et al. (1998). The Lambeth Conventions: guidelines for the study of arrhythmias in ischaemia infarction, and reperfusion. Cardiovasc. Res. 22(7): 447–455.WalkerMJCurtisMJHearseDJCampbellRWJanseMJYellonDM1998The Lambeth Conventions: guidelines for the study of arrhythmias in ischaemia infarction, and reperfusion22744745510.1093/cvr/22.7.4473252968Search in Google Scholar