<abstract xmlns="http://www.w3.org/1999/xhtml">

<p>Lately, RV dysfunction has emerged as a significant prognostic factor in heart failure with reduced ejection fraction (HFrEF). More so, recent data show a specific pattern of RV contraction in LBBB patients that is corrected by CRT, but not in patients with RV failure. The importance of RV evaluation in CRT patients is still under debate. Establishing the role of RV function in the setting of CRT may help identify patients with high risk of adverse events. Moreover, the changes induced by CRT upon RV may lead to a better understanding of the mechanisms behind CRT effects and may facilitate novel criteria for optimal selection of CRT candidates.</p>
</abstract>

Lately, RV dysfunction has emerged as a significant prognostic factor in heart failure with reduced ejection fraction (HFrEF). More so, recent data show a specific pattern of RV contraction in LBBB patients that is corrected by CRT, but not in patients with RV failure. The importance of RV evaluation in CRT patients is still under debate. Establishing the role of RV function in the setting of CRT may help identify patients with high risk of adverse events. Moreover, the changes induced by CRT upon RV may lead to a better understanding of the mechanisms behind CRT effects and may facilitate novel criteria for optimal selection of CRT candidates.

Right Ventricle and Cardiac Resynchronization Therapy. Spectator or Actor?

„Carol Davila” University of Medicine and Pharmacy

<trans-abstract xml:lang="fr" xmlns="http://www.w3.org/1999/xhtml">

<p>În ultima perioadă disfuncția de ventricul drept (VD) s-a dovedit a fiun element de prognostic important la pacienții cu insuficiență cardiacă cu fracție de ejecție redusă. Mai mult, date recente indică un pattern specific de contracție a VD la pacienții cu bloc de ramură stângă major, care este corectat de terapia de resincronizare cardiacă (CRT), nu însă și la pacienții cu disfuncție de VD. Importanța VD la pacienții care efectuează CRT este încă un subiect neclar. Stabilirea rolului VD la pacienții cu CRT ar putea facilita identificarea celor cu risc crescut de evenimente adverse. Mai mult, schimbările induse de CRT asupra VD ar putea duce la o mai bună înțelegere a efectelor tehnicii CRT și la optimizarea selecției pacienților.</p>
</trans-abstract>

În ultima perioadă disfuncția de ventricul drept (VD) s-a dovedit a fiun element de prognostic important la pacienții cu insuficiență cardiacă cu fracție de ejecție redusă. Mai mult, date recente indică un pattern specific de contracție a VD la pacienții cu bloc de ramură stângă major, care este corectat de terapia de resincronizare cardiacă (CRT), nu însă și la pacienții cu disfuncție de VD. Importanța VD la pacienții care efectuează CRT este încă un subiect neclar. Stabilirea rolului VD la pacienții cu CRT ar putea facilita identificarea celor cu risc crescut de evenimente adverse. Mai mult, schimbările induse de CRT asupra VD ar putea duce la o mai bună înțelegere a efectelor tehnicii CRT și la optimizarea selecției pacienților.

Romanian Journal of Cardiology

This work is licensed under the Creative Commons Attribution 4.0 International License.

{"article-title":"Right Ventricle and Cardiac Resynchronization Therapy. Spectator or Actor?"}

Lately, RV dysfunction has emerged as a significant prognostic factor in heart failure with reduced ejection fraction (HFrEF). More so, recent data show a...

Study	Number of patients	Methods	RV markers used	CRT effect on RV	Year
Rajagopalan³⁴	35	Echocardiography	TDI S’ velocity	Improvement after 3–6 months	2007
Donal et al.³⁵	50	Echocardiography	TAPSETDI S’ velocityRV fw S	Improvement after 3 months	2008
Scuteri et al.²⁷	44	Echocardiography	RV FACTAPSERV EDA, RV ESA	No reduction after 6 months	2009
Burri et al.³⁶	44	Radionuclide angiography	RV EF	Slightly improves RVEF after 6 months	2010
Leong et al.²⁵	848	Echocardiography	TAPSE	Improvement	2013
Damy et al.²⁸	814	Echocardiography	TAPSE	No effectLittle interaction with TAPSE	2013
Abdelhamid MA et al.³³	94	Echocardiography	RV diametersTAPSERV FACTDI S’ velocityRVGLS	RV reverse remodeling Improves RV systolic function after 6 months (5.9+/−1.2 months)	2017
Storsten et al.²³	24 /16 dogs	Echocardiography and ultrasonic dimension crystals and micromanometers.	RV strain	Increases workload of RV	2020

Right Ventricle and Cardiac Resynchronization Therapy. Spectator or Actor?

Article Category: Review

Pubblicato online: 03 mag 2022

Pagine: 303 - 310

DOI: https://doi.org/10.47803/rjc.2021.31.2.303

Parole chiave
right ventricle, cardiac resynchronization therapy, CRT, TAPSE, RV strain

© 2021 Silvia Deaconu et al., published by Sciendo

This work is licensed under the Creative Commons Attribution 4.0 International License.

Figure 1

Figure 2

Figure 3

Summary of studies analyzing effect of CRT upon RV

Right Ventricle and Cardiac Resynchronization Therapy. Spectator or Actor?

Article Category: Review

Pubblicato online: 03 mag 2022

Pagine: 303 - 310

DOI: https://doi.org/10.47803/rjc.2021.31.2.303

Parole chiaveright ventricle, cardiac resynchronization therapy, CRT, TAPSE, RV strain

© 2021 Silvia Deaconu et al., published by Sciendo

This work is licensed under the Creative Commons Attribution 4.0 International License.

Figure 1

Figure 2

Figure 3

Summary of studies analyzing effect of CRT upon RV

Parole chiave
right ventricle, cardiac resynchronization therapy, CRT, TAPSE, RV strain