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Recent progress in human placental transcriptomics

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Fig. 1

Pairwise alignment of examples showing differential splicing events identified in PAPPA and HBA2. Indication is made of the 5' untranslated region (UTR), coding DNA sequence (CDS), and 3' UTR. Adapted from [3].
Pairwise alignment of examples showing differential splicing events identified in PAPPA and HBA2. Indication is made of the 5' untranslated region (UTR), coding DNA sequence (CDS), and 3' UTR. Adapted from [3].

Gene Ontology (GO) and the Kyoto Encyclopedia of Genes and Genomes (KEGG) analysis of differentially expressed genes identified in lUGR-affected placentas. Adapted from [6].

ID Term Gene
G0:0050851 antigen receptor-mediated signaling pathway ITK, ZAP70, TESPA1, THEMIS, LCK
G0:0050852 T-cell receptor signaling pathway ITK, ZAP70, TESPA1, THEMIS, LCK
G0:0007159 leukocyte cell-cell adhesion SIRPG, ZAP70, TESPA1, IL7R, LCK
GO:1903037 regulation of leukocyte cell-cell adhesion SIRPG, ZAP70, TESPA1, IL7R, LCK
G0:0045321 leukocyte activation SIRPG, ITK, ZAP70, BCL11B, TESPA1, IL7R, THEMIS, LCK
GO:0046649 lymphocyte activation SIRPG, ITK, ZAP70, BCL11B, TESPA1, IL7R, THEMIS, LCK
G0:0042110 T-cell activation SIRPG, ITK, ZAP70, BCL11B, TESPA1, IL7R, THEMIS, LCK
G0:0002520 immune system development ITK, ZAP70, BCL11B, TESPA1, IL7R, THEMIS, LCK, LTB
GO:0048534 hematopoietic or lymphoid organ development ITK, ZAP70, BCL11B, TESPA1, IL7R, THEMIS, LCK, LTB
G0:0030097 hemopoiesis ITK, ZAP70, BCL11B, TESPA1, IL7R, THEMIS, LCK,
GO:0022409 positive regulation of cell-cell adhesion SIRPG, ZAP70, TESPA1, IL7R, LCK
GO:1903039 positive regulation of leukocyte cell-cell adhesion SIRPG, ZAP70, TESPA1, IL7R, LCK
G0:0050863 regulation of T-cell activation SIRPG, ZAP70, TESPA1, IL7R, LCK
G0:0002521 leukocyte differentiation ITK, ZAP70, BCL11B, TESPA1, IL7R, THEMIS, LCK
G0:0030098 lymphocyte differentiation ITK, ZAP70, BCL11B, TESPA1, IL7R, THEMIS, LCK
G0:0030217 T-cell differentiation ITK, ZAP70, BCL11B, TESPA1, IL7R, THEMIS, LCK
G0:0045058 T-cell selection ZAP70, BCL11B, THEMIS
GO:0043368 positive Cell selection ZAP70, BCL11B, THEMIS
G0:0033077 T-cell differentiation in thymus ZAP70, BCL11B, TESPA1, IL7R
GO:0051251 positive regulation of lymphocyte activation SIRPG, ZAP70, TESPA1, IL7R, LCK
G0:0050870 positive regulation of T-cell activation SIRPG, ZAP70, TESPA1, IL7R, LCK
GO:0004715 non-membrane spanning protein tyrosine kinase activity ITK, ZAP70, LCK
KEGG:04064 NF-kappa B signaling pathway ZAP70, LCK, LTB
KEGG:04660 T-cell receptor signaling pathway ITK, ZAP70, LCK
KEGG:05340 Primary immunodeficiency ZAP70, IL7R, LCK
eISSN:
2719-535X
Lingua:
Inglese
Frequenza di pubblicazione:
Volume Open
Argomenti della rivista:
Medicine, Clinical Medicine, Pediatrics and Juvenile Medicine, Paediatric Haematology and Oncology, Public Health