Magnesium chloride was given via drinking water (500 mg Mg/L) to rats exposed intragastrically to cadmium (cadmium 109) at a dose corresponding to 10 mg/kg diet for 7, 14, 21, and 28 d. The results provided the evidence that magnesium decreased cadmium retention in the duodenum, kidneys, and liver after 7 d. Significant reduction in cadmium retention was also found on days 14 d and 21 in kidneys. No significant decreases in cadmium retention in the organs examined were noted after 28 d. The results suggest that beneficial action of magnesium on body cadmium accumulation ceased with time after the two metal administration.
