<abstract xml:lang="en" xmlns="http://www.w3.org/1999/xhtml"><p>The 46,XX karyotype in a male is a rare sex chromosomal disorder. It mostly results from unequal crossovers between the X and Y chromosomes during meiosis. We here report a 32-year-old infertile male in whom seminal analysis showed azoospermia. Chromosomal analysis revealed a 46,XX karyotype and fluorescent <italic>in situ</italic> hybridization (FISH) showed the presence of the SRY gene. This report highlights the value of karyotyping and FISH analysis in cases of infertility.</p></abstract>

The 46,XX karyotype in a male is a rare sex chromosomal disorder. It mostly results from unequal crossovers between the X and Y chromosomes during meiosis. We here report a 32-year-old infertile male in whom seminal analysis showed azoospermia. Chromosomal analysis revealed a 46,XX karyotype and fluorescent in situ hybridization (FISH) showed the presence of the SRY gene. This report highlights the value of karyotyping and FISH analysis in cases of infertility.

An Sry-Positive 46,XX Male

Centre for Genetic Disorders, Guru Nanak Dev University, Amritsar, Punjab, India

Centre for Human Reproduction, Jalandhar, Punjab, India

Balkan Journal of Medical Genetics

{"article-title":"An Sry-Positive 46,XX Male"}

The 46,XX karyotype in a male is a rare sex chromosomal disorder. It mostly results from unequal crossovers between the X and Y chromosomes during meiosis. We...

An Sry-Positive 46,XX Male

Pubblicato online: 10 ott 2007

Pagine: 51 - 52

DOI: https://doi.org/10.2478/v10034-007-0010-9

Parole chiave
Azoospermia, XX male, Infertile

This content is open access.

An Sry-Positive 46,XX Male

Pubblicato online: 10 ott 2007

Pagine: 51 - 52

DOI: https://doi.org/10.2478/v10034-007-0010-9

Parole chiaveAzoospermia, XX male, Infertile

This content is open access.

Parole chiave
Azoospermia, XX male, Infertile