<abstract xml:lang="en" xmlns="http://www.w3.org/1999/xhtml"><bold>Background.</bold> We have analyzed the stability of CT to density curve of kilovoltage cone-beam computerized tomography (kV CBCT) imaging modality over the period of six months. We also, investigated the viability of using image value to density table (IVDT) generated at different time, for adaptive radiotherapy treatment planning. The consequences of target volume change and the efficacy of kV CBCT for adaptive planning issues is investigated.<bold>Materials and methods.</bold> Standard electron density phantom was used to establish CT to electron density calibrations curve. The CT to density curve for the CBCT images were observed for the period of six months. The kV CBCT scans used for adaptive planning was acquired with an on-board imager system mounted on a "Trilogy" linear accelerator. kV CBCT images were acquired for daily setup registration. The effect of variations in CT to density curve was studied on two clinical cases: prostate and lung.<bold>Results.</bold> The soft tissue contouring is superior in kV CBCT scans in comparison to mega voltage CT (MVCT) scans. The CT to density curve for the CBCT images was found steady over six months. Due to difficulty in attaining the reproducibility in daily setup for the prostate treatment, there is a day-to-day difference in dose to the rectum and bladder.<bold>Conclusions.</bold> There is no need for generating a new CT to density curve for the adaptive planning on the kV CBCT images. Also, it is viable to perform the adaptive planning to check the dose to target and organ at risk (OAR) without performing a new kV CT scan, which will reduce the dose to the patient.</abstract>

Background. We have analyzed the stability of CT to density curve of kilovoltage cone-beam computerized tomography (kV CBCT) imaging modality over the period of six months. We also, investigated the viability of using image value to density table (IVDT) generated at different time, for adaptive radiotherapy treatment planning. The consequences of target volume change and the efficacy of kV CBCT for adaptive planning issues is investigated.Materials and methods. Standard electron density phantom was used to establish CT to electron density calibrations curve. The CT to density curve for the CBCT images were observed for the period of six months. The kV CBCT scans used for adaptive planning was acquired with an on-board imager system mounted on a "Trilogy" linear accelerator. kV CBCT images were acquired for daily setup registration. The effect of variations in CT to density curve was studied on two clinical cases: prostate and lung.Results. The soft tissue contouring is superior in kV CBCT scans in comparison to mega voltage CT (MVCT) scans. The CT to density curve for the CBCT images was found steady over six months. Due to difficulty in attaining the reproducibility in daily setup for the prostate treatment, there is a day-to-day difference in dose to the rectum and bladder.Conclusions. There is no need for generating a new CT to density curve for the adaptive planning on the kV CBCT images. Also, it is viable to perform the adaptive planning to check the dose to target and organ at risk (OAR) without performing a new kV CT scan, which will reduce the dose to the patient.

Feasibility study on effect and stability of adaptive radiotherapy on kilovoltage cone beam CT

Department of Human Oncology, University of Wisconsin, Madison, WI, USA

Department of Medical Physics, University of Wisconsin, Madison, WI, USA

Vellore Institute of Technology University, Vellore, Tamil Nadu, India

Radiology and Oncology

Background. We have analyzed the stability of CT to density curve of kilovoltage cone-beam computerized tomography (kV CBCT) imaging modality over the period...

Feasibility study on effect and stability of adaptive radiotherapy on kilovoltage cone beam CT

Pubblicato online: 20 lug 2011

Pagine: 220 - 226

DOI: https://doi.org/10.2478/v10019-011-0024-5

Parole chiave
cone-beam computerized tomography, kV CBCT, CT to density table, electron density phantom, adaptive planning

This content is open access.

Feasibility study on effect and stability of adaptive radiotherapy on kilovoltage cone beam CT

Pubblicato online: 20 lug 2011

Pagine: 220 - 226

DOI: https://doi.org/10.2478/v10019-011-0024-5

Parole chiavecone-beam computerized tomography, kV CBCT, CT to density table, electron density phantom, adaptive planning

This content is open access.

Parole chiave
cone-beam computerized tomography, kV CBCT, CT to density table, electron density phantom, adaptive planning