<abstract xml:lang="en" xmlns="http://www.w3.org/1999/xhtml"><bold>Background.</bold> External beam radiotherapy (EBRT) for retinoblastoma has traditionally been done with conventional radiotherapy techniques which resulted high doses to the surrounding normal tissues.<bold>Case report.</bold> A 20 month-old girl with group D bilateral retinoblastoma underwent intensity modulated radiotherapy (IMRT) to both eyes after failing chemoreduction and focal therapies including cryotherapy and transpupillary thermotherapy. In this report, we discuss the use of IMRT as a method for reducing doses to adjacent normal tissues while delivering therapeutic doses to the tumour tissues compared with 3-dimensional conformal radiotherapy (3DCRT). At one year follow-up, the patient remained free of any obvious radiation complications.<bold>Conclusions.</bold> Image guided IMRT provides better dose distribution than 3DCRT in retinoblastoma eyes, delivering the therapeutic dose to the tumours and minimizing adjacent tissue damage.</abstract>

Background. External beam radiotherapy (EBRT) for retinoblastoma has traditionally been done with conventional radiotherapy techniques which resulted high doses to the surrounding normal tissues.Case report. A 20 month-old girl with group D bilateral retinoblastoma underwent intensity modulated radiotherapy (IMRT) to both eyes after failing chemoreduction and focal therapies including cryotherapy and transpupillary thermotherapy. In this report, we discuss the use of IMRT as a method for reducing doses to adjacent normal tissues while delivering therapeutic doses to the tumour tissues compared with 3-dimensional conformal radiotherapy (3DCRT). At one year follow-up, the patient remained free of any obvious radiation complications.Conclusions. Image guided IMRT provides better dose distribution than 3DCRT in retinoblastoma eyes, delivering the therapeutic dose to the tumours and minimizing adjacent tissue damage.

Intensity modulated radiotherapy (IMRT) in bilateral retinoblastoma

Department of Radiation Oncology, Acibadem University Istanbul, Turkey

Department of Ophthalmology, Ankara University Faculty of Medicine, Ankara, Turkey

Department of Radiation Oncology, Acibadem Maslak Hospital, Istanbul, Turkey

Radiology and Oncology

{"article-title":"Intensity modulated radiotherapy (IMRT) in bilateral retinoblastoma"}

Background. External beam radiotherapy (EBRT) for retinoblastoma has traditionally been done with conventional radiotherapy techniques which resulted high...

Intensity modulated radiotherapy (IMRT) in bilateral retinoblastoma

Pubblicato online: 23 apr 2010

Pagine: 194 - 198

DOI: https://doi.org/10.2478/v10019-010-0013-0

Parole chiave
retinoblastoma, radiotherapy, intensity modulated radiotherapy

This content is open access.

Intensity modulated radiotherapy (IMRT) in bilateral retinoblastoma

Pubblicato online: 23 apr 2010

Pagine: 194 - 198

DOI: https://doi.org/10.2478/v10019-010-0013-0

Parole chiaveretinoblastoma, radiotherapy, intensity modulated radiotherapy

This content is open access.

Parole chiave
retinoblastoma, radiotherapy, intensity modulated radiotherapy