<abstract xml:lang="en" xmlns="http://www.w3.org/1999/xhtml"><bold>Background.</bold> The aim of the study was to evaluate the clinical usefulness of 18F Fluorodeoxyglucose (FDG) positron emission tomography / computed tomography (PET/CT) in the management of nasopharyngeal carcinoma (NPC) in comparison to conventional imaging modalities.<bold>Methods.</bold> This retrospective study was done at Ospedale Niguarda, Milan, Italy. Data were acquired from 24 NPC patients between May 2003 and December 2006. They had FDG PET/CT and CT or MRI during the initial diagnosis and at follow-up. Each finding was tabulated and compared with tissue biopsy at diagnosis and clinical status during the follow up after the therapy. A statistical calculation was done to derive the value of each modality.<bold>Results.</bold> The sensitivity and accuracy of PET/CT and CT/MRI were equally high at diagnosis. At the follow up, a negative PET/CT finding suggested a complete remission with sensitivity and negative predictive value of 100%.<bold>Conclusions.</bold> 18F FDG PET/CT is a potential modality to be utilized in following up NPC patients for evaluating a response to therapy.</abstract>

Background. The aim of the study was to evaluate the clinical usefulness of 18F Fluorodeoxyglucose (FDG) positron emission tomography / computed tomography (PET/CT) in the management of nasopharyngeal carcinoma (NPC) in comparison to conventional imaging modalities.Methods. This retrospective study was done at Ospedale Niguarda, Milan, Italy. Data were acquired from 24 NPC patients between May 2003 and December 2006. They had FDG PET/CT and CT or MRI during the initial diagnosis and at follow-up. Each finding was tabulated and compared with tissue biopsy at diagnosis and clinical status during the follow up after the therapy. A statistical calculation was done to derive the value of each modality.Results. The sensitivity and accuracy of PET/CT and CT/MRI were equally high at diagnosis. At the follow up, a negative PET/CT finding suggested a complete remission with sensitivity and negative predictive value of 100%.Conclusions. 18F FDG PET/CT is a potential modality to be utilized in following up NPC patients for evaluating a response to therapy.

Imaging in nasopharyngeal carcinoma: the value of 18-Florine Fluorodeoxyglucose PET/CT in comparison to conventional imaging modalities CT and MRI

Nuclear Imaging Unit, Faculty Medicine and Health Science, University Putra Malaysia

Oncologia Medica Falck, Ospedale Niguarda Ca' Granda, Milan, Italy

Radiology Department, Hospital Serdang, Serdang, Malaysia

Department of Nuclear Medicine, Ospedale Niguardia Ca' Granda, Milan, Italy

Institute for Health Systems Research, Ministry Of Health Malaysia

Radiology and Oncology

Background. The aim of the study was to evaluate the clinical usefulness of 18F Fluorodeoxyglucose (FDG) positron emission tomography / computed tomography...

Imaging in nasopharyngeal carcinoma: the value of 18-Florine Fluorodeoxyglucose PET/CT in comparison to conventional imaging modalities CT and MRI

Pubblicato online: 26 ott 2009

Pagine: 247 - 257

DOI: https://doi.org/10.2478/v10019-009-0026-8

Parole chiave
positron emission tomography, computed tomography, magnetic resonance imaging, nasopharyngeal carcinoma, follow-up

This content is open access.

Imaging in nasopharyngeal carcinoma: the value of 18-Florine Fluorodeoxyglucose PET/CT in comparison to conventional imaging modalities CT and MRI

Pubblicato online: 26 ott 2009

Pagine: 247 - 257

DOI: https://doi.org/10.2478/v10019-009-0026-8

Parole chiavepositron emission tomography, computed tomography, magnetic resonance imaging, nasopharyngeal carcinoma, follow-up

This content is open access.

Parole chiave
positron emission tomography, computed tomography, magnetic resonance imaging, nasopharyngeal carcinoma, follow-up