<abstract xml:lang="en" xmlns="http://www.w3.org/1999/xhtml"><p>Accurate and sensitive methods were developed for simultaneous determination of methocarbamol and ibuprofen or diclofenac potassium in their binary mixtures, and in the presence of a methocarbamol related substance (guaifenesin) using mean centering of the ratio spectra method. The results obtained were statistically compared with the reported HPLC methods; no significant difference between the proposed methods and the reported methods was found regarding either accuracy or precision.</p></abstract>

Accurate and sensitive methods were developed for simultaneous determination of methocarbamol and ibuprofen or diclofenac potassium in their binary mixtures, and in the presence of a methocarbamol related substance (guaifenesin) using mean centering of the ratio spectra method. The results obtained were statistically compared with the reported HPLC methods; no significant difference between the proposed methods and the reported methods was found regarding either accuracy or precision.

Simultaneous determination of methocarbamol and ibuprofen or diclofenac potassium using mean centering of the ratio spectra method

Pharmaceutical Analytical Chemistry Department, Faculty of Pharmacy, Beni-Suef University, Beni-Suef, Egypt

Pharmaceutical Analytical Chemistry Department, Faculty of Pharmacy, Cairo University, Cairo, Egypt

Acta Pharmaceutica

Accurate and sensitive methods were developed for simultaneous determination of methocarbamol and ibuprofen or diclofenac potassium in their binary mixtures,...

Simultaneous determination of methocarbamol and ibuprofen or diclofenac potassium using mean centering of the ratio spectra method

Pubblicato online: 28 giu 2012

Pagine: 191 - 200

DOI: https://doi.org/10.2478/v10007-012-0016-z

Parole chiave
metokarbamol, diklofenak kalij, ibuprofen, centriranje srednjih vrijednosti spektralnih omjera, gvajfenezin

This content is open access.

Simultaneous determination of methocarbamol and ibuprofen or diclofenac potassium using mean centering of the ratio spectra method

Pubblicato online: 28 giu 2012

Pagine: 191 - 200

DOI: https://doi.org/10.2478/v10007-012-0016-z

Parole chiavemetokarbamol, diklofenak kalij, ibuprofen, centriranje srednjih vrijednosti spektralnih omjera, gvajfenezin

This content is open access.

Parole chiave
metokarbamol, diklofenak kalij, ibuprofen, centriranje srednjih vrijednosti spektralnih omjera, gvajfenezin