<abstract xml:lang="en" xmlns="http://www.w3.org/1999/xhtml"><p>Orally disintegrating tablets (ODTs), also known as fast melts, quick melts, fast disintegrating and orodispersible systems, have the unique property of disintegrating in the mouth in seconds without chewing and the need of water and are thus assumed to improve patient compliance. Conventional methods like direct compression, wet granulation, moulding, spray-drying, freeze-drying and sublimation were used to prepare ODTs. New advanced technologies like Orasolv®, Durasolv®, Wowtab®, Flashtab®, Zydis®, Flashdose®, Oraquick®, Lyoc®, Advatab®, Frosta®, Quick-Disc® and Nanomelt® have been introduced by some pharmaceutical companies for the production of ODTs. The main objective of this review is to give a comprehensive insight into conventional and recent technologies used for the preparation of ODTs.</p></abstract>

Orally disintegrating tablets (ODTs), also known as fast melts, quick melts, fast disintegrating and orodispersible systems, have the unique property of disintegrating in the mouth in seconds without chewing and the need of water and are thus assumed to improve patient compliance. Conventional methods like direct compression, wet granulation, moulding, spray-drying, freeze-drying and sublimation were used to prepare ODTs. New advanced technologies like Orasolv®, Durasolv®, Wowtab®, Flashtab®, Zydis®, Flashdose®, Oraquick®, Lyoc®, Advatab®, Frosta®, Quick-Disc® and Nanomelt® have been introduced by some pharmaceutical companies for the production of ODTs. The main objective of this review is to give a comprehensive insight into conventional and recent technologies used for the preparation of ODTs.

The technologies used for developing orally disintegrating tablets: A review

S. S. D. J. College of Pharmacy Neminagar, Chandwad, Dist-Nasik India

Acta Pharmaceutica

{"article-title":"The technologies used for developing orally disintegrating tablets: A review"}

Orally disintegrating tablets (ODTs), also known as fast melts, quick melts, fast disintegrating and orodispersible systems, have the unique property of...

The technologies used for developing orally disintegrating tablets: A review

Pubblicato online: 17 giu 2011

Pagine: 117 - 139

DOI: https://doi.org/10.2478/v10007-011-0020-8

Parole chiave
oralno raspadljive tablete, orodisperzibilne tablete, superdezintegratori, isporuka lijekova, brzo raspadljive tablete

This content is open access.

The technologies used for developing orally disintegrating tablets: A review

Pubblicato online: 17 giu 2011

Pagine: 117 - 139

DOI: https://doi.org/10.2478/v10007-011-0020-8

Parole chiaveoralno raspadljive tablete, orodisperzibilne tablete, superdezintegratori, isporuka lijekova, brzo raspadljive tablete

This content is open access.

Parole chiave
oralno raspadljive tablete, orodisperzibilne tablete, superdezintegratori, isporuka lijekova, brzo raspadljive tablete