<abstract xmlns="http://www.w3.org/1999/xhtml">

<p>Takotsubo cardiomyopathy (TC) is an acute cardiac condition triggered by emotional or physical stress. General anesthesia and sympathetic activation are possible triggers for TC. However, little is known about the role of sympathovagal activity in TC. In our report, we present a female patient, aged 62, who underwent thyroidectomy and at the end of the surgery developed cardiac complications. The patient had no chest pain, but had ST depression and negative T waves on the electrocardiogram (ECG). Cardiospecific enzyme troponin was elevated. Cardiac catheterization revealed unobstructed coronary arteries. Echo-cardiography revealed the enlargement of the left ventricle and ejection fraction of 40%. The patient was diagnosed with TC and dual antiplatelet therapy was introduced, a beta blocker and ACE inhibitor.It is possible that TC in perioperative period after thyroidectomy in this patient occured due to both sympathetic and parasympathetic activation. Probably, extraction of large thyroid induced vagal stimulation which resulted in hypotension and bradicardia. The patient was subsequently treated with adrenaline and atropine. In this case, sympathetic and parasympathetic activation in different intervals could result in the development of this condition.</p>
</abstract>

Takotsubo cardiomyopathy (TC) is an acute cardiac condition triggered by emotional or physical stress. General anesthesia and sympathetic activation are possible triggers for TC. However, little is known about the role of sympathovagal activity in TC. In our report, we present a female patient, aged 62, who underwent thyroidectomy and at the end of the surgery developed cardiac complications. The patient had no chest pain, but had ST depression and negative T waves on the electrocardiogram (ECG). Cardiospecific enzyme troponin was elevated. Cardiac catheterization revealed unobstructed coronary arteries. Echo-cardiography revealed the enlargement of the left ventricle and ejection fraction of 40%. The patient was diagnosed with TC and dual antiplatelet therapy was introduced, a beta blocker and ACE inhibitor.It is possible that TC in perioperative period after thyroidectomy in this patient occured due to both sympathetic and parasympathetic activation. Probably, extraction of large thyroid induced vagal stimulation which resulted in hypotension and bradicardia. The patient was subsequently treated with adrenaline and atropine. In this case, sympathetic and parasympathetic activation in different intervals could result in the development of this condition.

Takotsubo Cardiomyopathy Precipitated By Thyroidectomy - A Case Report

Faculty of Medicine, Department of Pharmacology, Clinical Pharmacology and Toxicology

Emergency Department, Clinic for Cardiology

Experimental and Applied Biomedical Research (EABR)

This work is licensed under the Creative Commons Attribution-NonCommercial-NoDerivatives 4.0 International License.

{"article-title":"Takotsubo Cardiomyopathy Precipitated By Thyroidectomy - A Case Report"}

Takotsubo cardiomyopathy (TC) is an acute cardiac condition triggered by emotional or physical stress. General anesthesia and sympathetic activation are...

Takotsubo Cardiomyopathy Precipitated By Thyroidectomy - A Case Report

Pubblicato online: 05 ago 2021

Pagine: 181 - 185

Ricevuto: 28 set 2018

Accettato: 31 dic 2018

DOI: https://doi.org/10.2478/sjecr-2018-0093

Parole chiave
takotsubo, cardiomyopathy, thyroid gland, sympathetic, parasympathetic

© 2021 Katarina Savic Vujovic et al., published by Sciendo

This work is licensed under the Creative Commons Attribution-NonCommercial-NoDerivatives 4.0 International License.

Takotsubo Cardiomyopathy Precipitated By Thyroidectomy - A Case Report

Pubblicato online: 05 ago 2021

Pagine: 181 - 185

Ricevuto: 28 set 2018

Accettato: 31 dic 2018

DOI: https://doi.org/10.2478/sjecr-2018-0093

Parole chiavetakotsubo, cardiomyopathy, thyroid gland, sympathetic, parasympathetic

© 2021 Katarina Savic Vujovic et al., published by Sciendo

This work is licensed under the Creative Commons Attribution-NonCommercial-NoDerivatives 4.0 International License.

Parole chiave
takotsubo, cardiomyopathy, thyroid gland, sympathetic, parasympathetic