<abstract xmlns="http://www.w3.org/1999/xhtml"><p>Acne necrotica is a rare disease, characterized by repeated cropping of inflammatory papules and papulo-pustules, which rapidly necrotize and leave varying degrees of varioliform scars that may lead to cicatricial alopecia when terminal hair-bearing sites are involved. In early lesions, pathology shows necrotizing lymphocytic folliculitis. We report a 63-year-old male patient with chronic, relapsing, umbilicated and centrally necrotic erythematous papules and papulo-pustules involving the frontal hairline area, face, and neck. Histopathology showed epidermal spongiosis and lymphocytic exocytosis, extensive necrosis and destruction of the follicular epithelium, a dense diffuse lymphohistiocytic infiltrate and necrosis of the perifolicular dermis. The diagnosis of acne necrotica was made based on the correlation of clinical and histopathological findings. A complete clinical remission was achieved with topical erythromycin and benzoyl peroxide.</p></abstract>

Acne necrotica is a rare disease, characterized by repeated cropping of inflammatory papules and papulo-pustules, which rapidly necrotize and leave varying degrees of varioliform scars that may lead to cicatricial alopecia when terminal hair-bearing sites are involved. In early lesions, pathology shows necrotizing lymphocytic folliculitis. We report a 63-year-old male patient with chronic, relapsing, umbilicated and centrally necrotic erythematous papules and papulo-pustules involving the frontal hairline area, face, and neck. Histopathology showed epidermal spongiosis and lymphocytic exocytosis, extensive necrosis and destruction of the follicular epithelium, a dense diffuse lymphohistiocytic infiltrate and necrosis of the perifolicular dermis. The diagnosis of acne necrotica was made based on the correlation of clinical and histopathological findings. A complete clinical remission was achieved with topical erythromycin and benzoyl peroxide.

Acne Necrotica (Varioliformis) – Case Report

Serbian Journal of Dermatology and Venereology

This work is licensed under the Creative Commons Attribution-NonCommercial-NoDerivatives 4.0 License.

{"article-title":"Acne Necrotica (Varioliformis) \u2013 Case Report"}

Acne necrotica is a rare disease, characterized by repeated cropping of inflammatory papules and papulo-pustules, which rapidly necrotize and leave varying...

Acne Necrotica (Varioliformis) – Case Report

Pubblicato online: 20 feb 2020

Pagine: 94 - 97

Ricevuto: 12 ott 2019

Accettato: 25 ott 2019

DOI: https://doi.org/10.2478/sjdv-2019-0014

Parole chiave
Acne Vulgaris, Cicatrix, Necrosis, Alopecia, Folliculitis, Erythromycin, Benzoyl Peroxide, Treatment Outcome

© 2019 Marija Nikolić et al., published by Sciendo

This work is licensed under the Creative Commons Attribution-NonCommercial-NoDerivatives 4.0 License.

Acne Necrotica (Varioliformis) – Case Report

Pubblicato online: 20 feb 2020

Pagine: 94 - 97

Ricevuto: 12 ott 2019

Accettato: 25 ott 2019

DOI: https://doi.org/10.2478/sjdv-2019-0014

Parole chiaveAcne Vulgaris, Cicatrix, Necrosis, Alopecia, Folliculitis, Erythromycin, Benzoyl Peroxide, Treatment Outcome

© 2019 Marija Nikolić et al., published by Sciendo

This work is licensed under the Creative Commons Attribution-NonCommercial-NoDerivatives 4.0 License.

Parole chiave
Acne Vulgaris, Cicatrix, Necrosis, Alopecia, Folliculitis, Erythromycin, Benzoyl Peroxide, Treatment Outcome