<abstract xmlns="http://www.w3.org/1999/xhtml"><p>The aim of this study was to investigate the usage of Dynamic Image Analysis for determination of size, shape and distribution of granules of microcrystalline cellulose, created by high shear granulation. A series of experiments was carried out to analyse the effect of process parameters on a created granule morphology. The amount of the granulation liquid and speed of the impeller have a significant effect on the median size granule value, the sphericity, the granule distribution width, but also on the granulation process yield.</p></abstract>

The aim of this study was to investigate the usage of Dynamic Image Analysis for determination of size, shape and distribution of granules of microcrystalline cellulose, created by high shear granulation. A series of experiments was carried out to analyse the effect of process parameters on a created granule morphology. The amount of the granulation liquid and speed of the impeller have a significant effect on the median size granule value, the sphericity, the granule distribution width, but also on the granulation process yield.

Dynamic Image Analysis to Determine Granule Size and Shape, for Selected High Shear Granulation Process Parameters

Slovak University of Technology in Bratislava

Faculty of Mechanical Engineering, Institute of Process Engineering

Strojnícky časopis - Journal of Mechanical Engineering

This work is licensed under the Creative Commons Attribution-NonCommercial-NoDerivatives 4.0 License.

The aim of this study was to investigate the usage of Dynamic Image Analysis for determination of size, shape and distribution of granules of microcrystalline...

Dynamic Image Analysis to Determine Granule Size and Shape, for Selected High Shear Granulation Process Parameters

Pubblicato online: 05 dic 2019

Pagine: 57 - 64

DOI: https://doi.org/10.2478/scjme-2019-0043

Parole chiave
High shear granulation, Dynamic Image Analysis, Microcrystalline cellulose

© 2019 Macho Oliver et al., published by Sciendo

This work is licensed under the Creative Commons Attribution-NonCommercial-NoDerivatives 4.0 License.

Dynamic Image Analysis to Determine Granule Size and Shape, for Selected High Shear Granulation Process Parameters

Pubblicato online: 05 dic 2019

Pagine: 57 - 64

DOI: https://doi.org/10.2478/scjme-2019-0043

Parole chiaveHigh shear granulation, Dynamic Image Analysis, Microcrystalline cellulose

© 2019 Macho Oliver et al., published by Sciendo

This work is licensed under the Creative Commons Attribution-NonCommercial-NoDerivatives 4.0 License.

Parole chiave
High shear granulation, Dynamic Image Analysis, Microcrystalline cellulose