<abstract xml:lang="en" xmlns="http://www.w3.org/1999/xhtml"><p>The effects of ivermectin were studied in laboratory rats naturally infected with the pinworm Syphacia muris. Ivermectin was administered over four 5-days periods in drinking water; the ivermectin dose was 2.5 mg/kg of body weight per day. All the rats were weighed every five days and their ova production was monitored by a cellophane — tape test. Every fifth day six males and six females from the experimental group were euthanized and examined for adult pinworms and larvae. The rats’ health condition, behaviour and consumption of food and water were monitored every day. The aim of this study was to investigate the effectiveness of orally administered ivermectin as a treatment against adult pinworms and their larvae in laboratory rat colonies.</p></abstract>

The effects of ivermectin were studied in laboratory rats naturally infected with the pinworm Syphacia muris. Ivermectin was administered over four 5-days periods in drinking water; the ivermectin dose was 2.5 mg/kg of body weight per day. All the rats were weighed every five days and their ova production was monitored by a cellophane — tape test. Every fifth day six males and six females from the experimental group were euthanized and examined for adult pinworms and larvae. The rats’ health condition, behaviour and consumption of food and water were monitored every day. The aim of this study was to investigate the effectiveness of orally administered ivermectin as a treatment against adult pinworms and their larvae in laboratory rat colonies.

Drinking water ivermectin treatment for eradication of pinworm infections from laboratory rat colonies

Department of Laboratory Animal Breeding and Hygiene, Institute of Physiology, Academy of Sciences of the Czech Republic, Videnska 1083, 142 20, Prague 4-Krc, Czech Republic

Department of Zoology and Fisheries, Faculty of Agrobiology, Food and Natural Resources, Czech University of Life Sciences in Prague, Kamycka 129, 165 21, Prague 6-Suchdol, Czech Republic

Department of Veterinary Sciences, Faculty of Agrobiology, Food and Natural Resources, Czech University of Life Sciences in Prague, Kamycka 129, 165 21, Prague 6-Suchdol, Czech Republic

Helminthologia

This work is licensed under the Creative Commons Attribution-NonCommercial-NoDerivatives 3.0 License.

The effects of ivermectin were studied in laboratory rats naturally infected with the pinworm Syphacia muris. Ivermectin was administered over four 5-days...

Drinking water ivermectin treatment for eradication of pinworm infections from laboratory rat colonies

Pubblicato online: 17 dic 2010

Pagine: 233 - 237

DOI: https://doi.org/10.2478/s11687-010-0036-5

Parole chiave
Syphacia muris, Aspiculuris tetraptera, ivermectin, laboratory rat, pinworm

© 2010 Institute of Parasitology, SAS, Košice, Slovakia

This work is licensed under the Creative Commons Attribution-NonCommercial-NoDerivatives 3.0 License.

Drinking water ivermectin treatment for eradication of pinworm infections from laboratory rat colonies

Pubblicato online: 17 dic 2010

Pagine: 233 - 237

DOI: https://doi.org/10.2478/s11687-010-0036-5

Parole chiaveSyphacia muris, Aspiculuris tetraptera, ivermectin, laboratory rat, pinworm

© 2010 Institute of Parasitology, SAS, Košice, Slovakia

This work is licensed under the Creative Commons Attribution-NonCommercial-NoDerivatives 3.0 License.

Parole chiave
Syphacia muris, Aspiculuris tetraptera, ivermectin, laboratory rat, pinworm