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Glycemic trends and reduced insulin requirements in adolescents with type 1 diabetes during a therapeutic recreational camp: Insights from continuous glucose monitoring

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06 ago 2025
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Background

Appropriate management of glycemic control in type 1 diabetes mellitus (T1DM) is challenging. Severe hypoglycemia represents a feared acute complication. Diabetes camps provide ideal settings for implementation of Continuous Glucose Monitoring (CGM) technologies.

Methods

A prospective interventional study was conducted on 41 T1DM adolescents between August 28 - September 2, 2023 in a therapeutic recreational camp in Șăulia, Romania. Key features: use of Dexcom One sensor with a receiver, six scheduled meals per day, standardized hypoglycemia protocol, therapeutic activities with physical exercise. Demographic data, information regarding insulin types, doses, carbohydrate intake, CGM data were collected in the first (D1) and last (D5) days of the camp.

Results

Mean age of participants was 14.9 years±1.25 (SD), 61% were females, 71% from urban areas. Of all participants, 42% had continuous subcutaneous insulin infusion (CSII) therapy and 71% previously used CGM devices. Time in range (TIR) levels increased (D1: 59.7% vs. D5: 65.4%, p=0.152) due to reduction of both time below range (TBR: D1: 6.4% vs. D5: 2.1%, p=0.061) and time above range (TAR: D1: 33.78% vs. D5: 32.03%, p=0.623). Significant reduction in insulin doses (p=0.001) occurred (D1: 52.5±18.45 IU vs. D5: 47.6±15.63), more evident in females, and in patients on basal-bolus (BB) insulin therapy. Insulin sensitivity factor also increased significantly (D1: 38.7±19.34 mg/dL vs. D5: 42.4±15.5 mg/dL, p=0.050).

Conclusions

Improved glycemic control was observed along with a decline in insulin requirements during the study. A strictly controlled environment, adapted diet and modern tehnology contribute to the achievement of better metabolic control in T1DM.

Lingua:
Inglese
Frequenza di pubblicazione:
4 volte all'anno
Argomenti della rivista:
Scienze biologiche, Biologia molecolare, Buiochimica, Biologia umana, Microbiologia e virologia