Incidence rate of postoperative cognitive dysfunction at different anesthetic depths and its correlation with serum levels of RAGE, NR2B, CREB, and NFL
This work is licensed under the Creative Commons Attribution 4.0 International License.
Liu B, Huang D, Guo Y, Sun X, Chen C, Zhai X, et al. Recent advances and perspectives of postoperative neurological disorders in the elderly surgical patients. CNS Neurosci Ther. 2022;28(4):470-83. DOI: 10.1111/cns.13763Search in Google Scholar
Tan XX, Qiu LL, Sun J. Research Progress on the Role of Inflammatory Mechanisms in the Development of Postoperative Cognitive Dysfunction. Biomed Res Int. 2021;2021:3883204. DOI: 10.1155/2021/3883204Search in Google Scholar
Gendy AS, Abd-Elrahman AI, Elfeky EE, Ezz S. The effect of general anesthesia on geriatric patients’ cognitive function. Menoufia Med J. 2020;33(2):346-50. DOI: 10.4103/mmj.mmj_288_19Search in Google Scholar
Wang X, Chen X, Wu F, Liu Y, Yang Y, Chen W, et al. Relationship between postoperative biomarkers of neuronal injury and postoperative cognitive dysfunction: A meta-analysis. PLoS one. 2023;18(4):e0284728. DOI: 10.1371/journal.pone.0284728Search in Google Scholar
Liu Y, Yang W, Xue J, Chen J, Liu S, Zhang S, et al. Neuroinflammation: The central enabler of postoperative cognitive dysfunction. Biomed Pharmacother. 2023;167:115582. DOI: 10.1016/j.biopha.2023.115582Search in Google Scholar
Yang J, Dong HQ, Liu YH, Ji MH, Zhang X, Dai HY, et al. Laparotomy-Induced Peripheral Inflammation Activates NR2B Receptors on the Brain Mast Cells and Results in Neuroinflammation in a Vagus Nerve-Dependent Manner. Front Cell Neurosci. 2022;16:771156. DOI: 10.3389/fncel.2022.771156Search in Google Scholar
Huang Y, Yang Y, Ye C, Liu Z, Wei F. The m6A Reader YTHDF1 Improves Sevoflurane-Induced Neuronal Pyroptosis and Cognitive Dysfunction Through Augmenting CREB-BDNF Signaling. Neurochem Res. 2023;48(12):3625-38. DOI: 10.1007/s11064-023-04007-6Search in Google Scholar
Wiberg S, Holmgaard F, Zetterberg H, Nilsson JC, Kjaergaard J, Wanscher M, et al. Biomarkers of Cerebral Injury for Prediction of Postoperative Cognitive Dysfunction in Patients Undergoing Cardiac Surgery. J Cardiothorac Vasc Anesth. 2022;36(1):125-32. DOI: 10.1053/j.jvca.2021.05.016Search in Google Scholar
Gallegos M, Morgan ML, Cervigni M, Martino P, Murray J, Calandra M, et al. 45 Years of the mini-mental state examination (MMSE): A perspective from ibero-america. Dement Neuropsychol. 2022;16(4):384-7. DOI: 10.1590/1980-5764-dn-2021-0097Search in Google Scholar
Zhang W, Yu H, Duan Z, Yu T, Li X. Anesthesia depth evaluation algorithm based on permutation and combination entropy. Neural Computing and Applications. 2022;34(9):6647-60. DOI: 10.1007/s00521-021-06030-6Search in Google Scholar
Yang X, Huang X, Li M, Jiang Y, Zhang H. Identification of individuals at risk for postoperative cognitive dysfunction (POCD). Ther Adv Neurol Disord. 2022;15:17562864221114356. DOI: 10.1177/17562864221114356Search in Google Scholar
Shi X, Chen X, Ni J, Zhang Y, Liu H, Xu C, et al. Systematic review and meta-analysis of the prognostic value of Narcotrend monitoring of different depths of anesthesia and different Bispectral Index (BIS) values for cognitive dysfunction after tumor surgery in elderly patients. Ann Transl Med. 2022;10(4):186. DOI: 10.21037/atm-22-90Search in Google Scholar
Bhushan S, Li Y, Huang X, Cheng H, Gao K, Xiao Z. Progress of research in postoperative cognitive dysfunction in cardiac surgery patients: A review article. Int J Surg. 2021;95:106163. DOI: 10.1016/j.ijsu.2021.106163Search in Google Scholar
Needham MJ, Webb CE, Bryden DC. Postoperative cognitive dysfunction and dementia: what we need to know and do. Br J Anaesth. 2017;119(suppl_1):i115-25. DOI: 10.1093/bja/aex354Search in Google Scholar
He B, Zhang N, Peng M. Meta-analysis of the effect of entropy-assisted general anesthesia on the quality of postoperative recovery. Medicine. 2023;102(25):e34091. DOI: 10.1097/MD.0000000000034091Search in Google Scholar
Huang H, Li Y, Wang X, Zhang Q, Zhao J, Wang Q. Electroacupuncture pretreatment protects against anesthesia/surgery-induced cognitive decline by activating CREB via the ERK/MAPK pathway in the hippocampal CA1 region in aged rats. Aging. 2023;15(20):11227-43. DOI: 10.18632/aging.205124Search in Google Scholar
Hua M, Min J. Postoperative Cognitive Dysfunction and the Protective Effects of Enriched Environment: A Systematic Review. Neurodegener Dis. 2020;20(4):113-22. DOI: 10.1159/000513196Search in Google Scholar
Zhou H, Luo T, Wei C, Shen W, Li R, Wu A. RAGE antagonism by FPSZM1 attenuates postoperative cognitive dysfunction through inhibition of neuroinflammation in mice. Mol Med Rep. 2017;16(4):4187-94. DOI: 10.3892/mmr.2017.7074Search in Google Scholar
Xu F, Cong P, Zhang B, Dong H, Zuo W, Wu T, et al. A decrease in NR2B expression mediated by DNA hypermethylation induces perioperative neurocognitive disorder in aged mice. CNS Neurosci Ther. 2023;29(5):1229-42. DOI: 10.1111/cns.14097Search in Google Scholar
Guan S, Li Y, Xin Y, Wang D, Lu P, Han F, et al. Deciphering the dual role of N-methyl-D-Aspartate receptor in postoperative cognitive dysfunction: A comprehensive review. Eur J Pharmacol. 2024;971:176520. DOI: 10.1016/j.ejphar.2024.176520Search in Google Scholar
Fu W, Xu H, Zhao T, Xu J, Wang F. Effects of dexmedetomidine combined with etomidate on postoperative cognitive function in older patients undergoing total intravenous anaesthesia: a randomized, double-blind, controlled trial. BMC Geriatr. 2024;24(1):97. DOI: 10.1186/s12877-024-04726-7Search in Google Scholar
Wiberg S, Holmgaard F, Zetterberg H, Nilsson JC, Kjaergaard J, Wanscher M, et al. Biomarkers of cerebral injury for prediction of postoperative cognitive dysfunction in patients undergoing cardiac surgery. J Cardiothorac Vasc Anesth. 2022;36(1):125-32. DOI: 10.1053/j.jvca.2021.05.016Search in Google Scholar
Wang H, Ma G, Min J, Li J, Shan W, Zuo Z. Inhibition of ERK/CREB signaling contributes to postoperative learning and memory dysfunction in neonatal rats. J Mol Med. 2023;101(3):265-78. DOI: 10.1007/s00109-023-02285-9Search in Google Scholar
Brodier EA, Cibelli M. Postoperative cognitive dysfunction in clinical practice. BJA Educ. 2021;21(2):75-82. DOI: 10.1016/j.bjae.2020.10.004Search in Google Scholar
Liu P, Zhao S, Qiao H, Li T, Mi W, Xu Z, et al. Does propofol definitely improve postoperative cognitive dysfunction?-a review of propofol-related cognitive impairment. Acta Biochim Biophys Sin. 2022;54(7):875-81. DOI: 10.3724/abbs.2022067Search in Google Scholar
Lu X, Jin X, Yang S, Xia Y. The correlation of the depth of anesthesia and postoperative cognitive impairment: a meta-analysis based on randomized controlled trials. J Clin Anesth 2018;45:55-9. DOI: 10.1016/j.jclinane.2017.12.002Search in Google Scholar