<abstract xmlns="http://www.w3.org/1999/xhtml"><bold>Introduction</bold>: Perforated appendicitis (PA) in children is associated with a considerable risk for postoperative complications (POCs) such as wound infection and intra-abdominal abscess.The <bold>aim</bold> of this study was to determine the diagnostic accuracy of hematological parameters in the early POC detection in children after PA surgery.<bold>Materials and Methods</bold>: The study enrolled 71 patients with PA divided into two groups: 14 patients with POC (POC+ group) and 57 patients without POC (POC− group). Clinical and hematological parameters were followed preoperatively, prior to the surgery (PRO) and postoperatively on day 2 (POD2) and day 4 (POD4).<bold>Results</bold>: The POC+ group had longer duration of higher axillar temperature as well as extended intensive and inpatient care. This group also had a significantly lower absolute neutrophil count ratio between POD2 and POD4. According to the receiver operating characteristic curve analysis, relative neutrophil count on POD4 higher than 71.8% and the ratio of absolute neutrophil count between POD2 and POD4 lower than 44.5% were found to be useful for predicting POC.<bold>Conclusion</bold>: Absolute neutrophil count ratio between POD2 and POD4 and relative neutrophil count at POD4 could be efficient in identifying children at higher risk of developing POC after PA surgery.</abstract>

Introduction: Perforated appendicitis (PA) in children is associated with a considerable risk for postoperative complications (POCs) such as wound infection and intra-abdominal abscess.The aim of this study was to determine the diagnostic accuracy of hematological parameters in the early POC detection in children after PA surgery.Materials and Methods: The study enrolled 71 patients with PA divided into two groups: 14 patients with POC (POC+ group) and 57 patients without POC (POC− group). Clinical and hematological parameters were followed preoperatively, prior to the surgery (PRO) and postoperatively on day 2 (POD2) and day 4 (POD4).Results: The POC+ group had longer duration of higher axillar temperature as well as extended intensive and inpatient care. This group also had a significantly lower absolute neutrophil count ratio between POD2 and POD4. According to the receiver operating characteristic curve analysis, relative neutrophil count on POD4 higher than 71.8% and the ratio of absolute neutrophil count between POD2 and POD4 lower than 44.5% were found to be useful for predicting POC.Conclusion: Absolute neutrophil count ratio between POD2 and POD4 and relative neutrophil count at POD4 could be efficient in identifying children at higher risk of developing POC after PA surgery.

Predictive Value of Neutrophil Count for Postoperative Complications in Children after Surgery of Perforated Appendicitis

Department of Anesthesiology and Reanimatology, Faculty of Medicine

Department of Surgery with Anesthesiology, Faculty of Medicine

Department of Anesthesiology, Reanimatology and Intensive Therapy

Department of Immunology, Faculty of Medicine

Revista Romana de Medicina de Laborator

This work is licensed under the Creative Commons Attribution-NonCommercial-NoDerivatives 3.0 License.

Introduction: Perforated appendicitis (PA) in children is associated with a considerable risk for postoperative complications (POCs) such as wound infection...

Predictive Value of Neutrophil Count for Postoperative Complications in Children after Surgery of Perforated Appendicitis

Pubblicato online: 29 gen 2021

Pagine: 77 - 84

Ricevuto: 22 ott 2020

Accettato: 29 dic 2020

DOI: https://doi.org/10.2478/rrlm-2021-0008

Parole chiave
perforated appendicitis, predictors of postoperative complication, children

© 2021 Vesna Marjanovic et al., published by Sciendo

This work is licensed under the Creative Commons Attribution-NonCommercial-NoDerivatives 3.0 License.

Predictive Value of Neutrophil Count for Postoperative Complications in Children after Surgery of Perforated Appendicitis

Pubblicato online: 29 gen 2021

Pagine: 77 - 84

Ricevuto: 22 ott 2020

Accettato: 29 dic 2020

DOI: https://doi.org/10.2478/rrlm-2021-0008

Parole chiaveperforated appendicitis, predictors of postoperative complication, children

© 2021 Vesna Marjanovic et al., published by Sciendo

This work is licensed under the Creative Commons Attribution-NonCommercial-NoDerivatives 3.0 License.

Parole chiave
perforated appendicitis, predictors of postoperative complication, children