[1. Sena CM, Pereira AM, Seica R. Endothelial dysfunction- A major mediator of diabetic vascular disease. Biochim Biophys Acta. 2013 Dec;1832(12):2216-31. DOI: 10.1016/j.bbadis.2013.08.00610.1016/j.bbadis.2013.08.006]Open DOISearch in Google Scholar
[2. Sundaram B, Singhal K, Sandhir R. Anti-atherogenic effect of chromium picolinate in streptozotocin-induced experimental diabetes. J Diabetes. 2013 Mar;5(1):43-50. DOI: 10.1111/j.1753-0407.2012.00211.x10.1111/j.1753-0407.2012.00211.x]Open DOISearch in Google Scholar
[3. Chis IC, Muresan A, Adrian O, Andras LN, Simona C. Protective effects of Quercetin and chronic moderate exercise (training) against oxidative stress in the liver tissue of streptozotocin-induced diabetic rats. Physiol Int. 2016 Mar;103(1):49-64. DOI: 10.1556/036.103.2016.1.510.1556/036.103.2016.1.5]Open DOISearch in Google Scholar
[4. Tiwari BK, Pandey KB, Abidi AB, Rizvi SI. Markers of Oxidative Stress during Diabetes Mellitus. J Biomark. 2013 Dec; 2013:378790. DOI:10.1155/378790. DOI: 10.1155/2013/37879010.1155/378790.DOI:10.1155/2013/378790]Open DOISearch in Google Scholar
[5. Szabo C. Role of nitrosative stress in the pathogenesis of diabetic vascular dysfunction. Br J Pharmacol. 2009 Mar;156(5):713-27. DOI: 10.1111/j.1476-5381.2008.00086.x10.1111/j.1476-5381.2008.00086.x]Open DOISearch in Google Scholar
[6. Fowler MJ. Microvascular and Macrovascular Complications of Diabetes. Clin Diabetes 2008 Apr;26(2):77-82. DOI: 10.2337/diaclin.26.2.7710.2337/diaclin.26.2.77]Open DOISearch in Google Scholar
[7. Umeno A, Horie M, Murotomi K, Nakajima Y, Yoshida Y. Antioxidative and antidiabetic effects of natural polyphenols and isoflavones. Molecules. 2016 May;21(6):708. DOI:10.3390/21060708. DOI: 10.3390/molecules2106070810.3390/21060708.DOI:10.3390/21060708]Open DOISearch in Google Scholar
[8. Wajima D, Nakagawa I, Takamura Y, Aketa S, Yonezawa T, Nakase H. Carotid artery stenosis is exacerbated in spontaneously obese model rats with diabetes. J Atheroscler Thromb. 2014 Jul;21(12):1253-9. DOI: 10.5551/jat.2466110.5551/jat.24661]Open DOISearch in Google Scholar
[9. Boots AW, Haenen GR, Bast A. Health effects of quercetin: From antioxidant to nutraceutical. Eur J Pharmacol. 2008 May;585(2-3):325-37. DOI: 10.1016/j.ejphar.2008.03.00810.1016/j.ejphar.2008.03.008]Open DOISearch in Google Scholar
[10. Pashevin DA, Tumanovska LV, Dosenko VE, Nagibin VS, Gurianova VL, Moibenko AA. Antiatherogenic effect of quercetin is mediated by proteasome inhibition in the aorta and circulating leukocytes. Pharmacol Rep. 2011 Mar;63(4):1009-18. DOI: 10.1016/S1734-1140(11)70617-X10.1016/S1734-1140(11)70617-X]Search in Google Scholar
[11. Larson AJ, Symons JD, Jalili T. Therapeutic potential of quercetin to decrease blood pressure: Review of efficacy and mechanisms. Adv Nutr. 2012 Jan;3(1):39-46. DOI: 10.3945/an.111.00127110.3945/.111.001271]Open DOISearch in Google Scholar
[12. Jeong SM, Kang MJ, Choi HN, Kim JH, Kim JI. Quercetin ameliorates hyperglycemia and dyslipidemia and improves antioxidant status in type 2 diabetic db/db mice. Nutr Res Pract. 2012 Jun;6(3):201-7. DOI: 10.4162/nrp.2012.6.3.20110.4162/nrp.2012.6.3.201339578422808343]Open DOISearch in Google Scholar
[13. Kim JH, Kang MJ, Choi HN, Jeong SM, Lee YM, Kim JI. Quercetin attenuates fasting and postprandial hyperglycemia in animal models of diabetes mellitus. Nutr Res Pract 2011 Apr;52):107-11. DOI: 10.4162/nrp.2011.5.2.10710.4162/nrp.2011.5.2.107308579821556223]Open DOISearch in Google Scholar
[14. Chis IC, Coseriu A, Ramona S, Adrian O, Andras LN, Simona C. In vivo effects of Quercetin in association with moderate exercise training in improving strep-tozotocin-induced aortic tissue injuries. Molecules. 2015 DEc;20(12):21770-86. DOI: 10.3390/molecules20121980210.3390/201219802]Open DOISearch in Google Scholar
[15. Chiş IC, Baltaru D, Dumitrovici A, Coseriu A, Radu BC, Moldovan R, Mureşan A. Quercetin ameliorate oxidative/nitrosative stress in the brain of rats exposed to intermittent hypobaric hypoxia. Rev Virtual Quim. 2016 Mar;8(2):369-83. DOI: 10.5935/1984-6835.2016002710.5935/1984-6835.20160027]Open DOISearch in Google Scholar
[16. Chiş IC, Baltaru D, Clichici S, Oniga O, Cojocaru I, Nastasă C. The Effects of a 5-Chromen-yl-thiazolidin-2,4-dione Derivative in Alleviating Oxidative Stress in AdjuvantInduced Arthritis. Rev Chim. 2018 Sep;9(69): 2361-65.10.37358/RC.18.9.6534]Search in Google Scholar
[17. Chiş IC, Baltaru D, Dumitrovici A, Coseriu A, Radu BC, Moldovan R, Mureşan A. Protective effects of quercetin from oxidative/nitrosative stress under intermittent hypobaric hypoxia exposure in the rat’s heart. Physiol Int. 2018 Sep;105(3):233-46. DOI: 10.1556/2060.105.2018.3.2310.1556/2060.105.2018.3.2330282485]Open DOISearch in Google Scholar
[18. Pyun SB, Kwon HK, Uhm CS. Effect of exercise on reinnervating soleus muscle after sciatic nerve injury in rats. J Korean Acad Rehabil Med. 1999;23:1063-75.]Search in Google Scholar
[19. Teixeira de Lemos E, Pinto R, Oliveira J, Garrido P, Sereno J, Mascarenhas-Melo F, et al. Differential Effects of Acute (Extenuating) and Chronic (Training) Exercise on Inflammation and Oxidative Stress Status in an Animal Model of Type 2 Diabetes Mellitus. Mediat Inflamm. 2011 Nov;2011:253061. DOI:10.1155/2011/253061. DOI: 10.1155/2011/25306110.1155/2011/253061323588322174491]Search in Google Scholar
[20. Zhang H, Zhang C. Vasoprotection by dietary supplements and exercise: Role of TNFα signaling. Exp Diabetes Res. 2011 Nov;2012: 972679. DOI:10.1155/2012/972679. DOI: 10.1155/2012/97267910.1155/2012/972679320637022110483]Search in Google Scholar
[21. Lee S, Park Y Dellsperger KC, Zhang C. Exercise training improves endothelial function via adiponectin-dependent and independent pathways in type 2 diabetic mice. Am J Physiol Heart Circ Physiol. 2011 Aug;301(2):H306-14. DOI: 10.1152/ajpheart.01306.201010.1152/ajpheart.01306.2010315467021602470]Open DOISearch in Google Scholar
[22. Coskun O, Ocakci A, Bayraktaroglu T, Kanter M. Exercise training prevents and protects streptozotocininduced oxidative stress and beta-cell damage in rat pancreas. Tohoku J Exp Med. 2004 Jul;203(3):145-54. DOI: 10.1620/tjem.203.14510.1620/tjem.203.14515240923]Open DOISearch in Google Scholar
[23. Rakieten N, Rakieten ML, Nadkarni MR. Studies on the diabetogenic action of streptozotocin (NSC-37917). Cancer Chemother Rep. 1963 May;29:91-8.]Search in Google Scholar
[24. Chang KS, Stevens WC. Endothelium-dependent increase in vascular sensitivity to phenylephrine in long-term streptozotocin diabetic rat aorta. Br J Pharmacol. 1992 Dec;107(4):983-90. DOI: 10.1111/j.1476-5381.1992.tb13395.x10.1111/j.1476-5381.1992.tb13395.x19079201467844]Open DOISearch in Google Scholar
[25. Chis IC, Clichici A, Nagy AL, Oros A, Catoi C, Clichici S. Quercetin in association with moderate exercise training attenuates injuries induced by experimental diabetes in sciatic nerves. Journal of physiology and pharmacology: an official journal of the Polish Physiological. 2017 Dec;68(6):877-86.]Search in Google Scholar
[26. Szkudelski T. The mechanism of alloxan and streptozotocin action of β-cells of the rat pancreas. Physiol Res. 2001;50(6):537-46.]Search in Google Scholar
[27. Oelze M, Knorr M, Schuhmacher S, Heeren T, Otto C, Schulz E, et al. Vascular dysfunction in streptozotocin-induced experimental diabetes strictly depends on insulin deficiency. J Vasc Res. 2011 Jan;48:275-84. DOI: 10.1159/00032062710.1159/00032062721273782]Open DOISearch in Google Scholar
[28. Searls Y, Smirnova IV, Vanhoose L, Fegley B, Loga-nathan R, Stehno-Bittel L. Time-dependent alterations in rat macrovessels with type 1 diabetes. Exp Diabetes Res. 2012 Jan. DOI:10/1155/2012/278620. DOI: 10.1155/2012/27862010.1155/2012/278620327054722315586]Search in Google Scholar
[29. Conti M, Morand PC, Levillain P. Improved fluoromeric determination of malonaldehyde. Clin Chem. 1991 Jul;37(7):1273-5.10.1093/clinchem/37.7.1273]Search in Google Scholar
[30. Kakkar P, Das B, Viswanthan PN. A modified spectrophotometric assay of superoxide dismutase (SOD). Indian J Biochem Biophys. 1984 Apr;21:130-2.]Search in Google Scholar
[31. Vats P, Singh VK, Singh SN, Singh SB. Glutathione metabolism under high-altitude stress and effect of antioxidant supplementation. Aviation, Space and Environmental Medicine. 2008 Dec;79(12):1106-11. DOI: 10.3357/ASEM.2305.200810.3357/ASEM.2305.200819070306]Open DOISearch in Google Scholar
[32. Avogaro A, Albiero M, Menegazzo L, de Kreutzenberg S, Fadini GP. Endothelial dysfunction in diabetes: The role of reparatory mechanisms. Diabetes Care. 2011 May; 34(Suppl 2):S285-90. DOI: 10.2337/dc11-s23910.2337/dc11-s239363219421525470]Open DOISearch in Google Scholar
[33. Alam MM, Meerza D, Naseem I. Protective effect of quercetin on hyperglycemia, oxidative stress and DNA damage in alloxan induced type 2 diabetic mice. Life Sci. 2014 Jul;109(1):8-14. DOI: 10.1016/j.lfs.2014.06.00510.1016/j.lfs.2014.06.00524946265]Open DOISearch in Google Scholar
[34. Rocha RE, Coelho I, Pequito DC, Yamagushi A, Borghetti G, Yamazaki RK, et al. Interval training attenuates the metabolic disturbances in type 1 diabetes rat model. Arq Bras Endocrinol Metab. 2013;57:594-602. DOI: 10.1590/S0004-2730201300080000310.1590/S0004-27302013000800003]Open DOISearch in Google Scholar
[35. Akazawa S, Tojikubo M, Nakano Y, Nakamura S, Tamai H, Yonemoto K, et al. Usefulness of carotid plaque (sum and maximum of plaque thickness) in combination with intima-media thickness for the detection of coronary artery disease in asymptomatic patients with diabetes. J Diabetes Investig. 2016 May;7(3):396-403. DOI: 10.1111/jdi.1240310.1111/jdi.12403484789527330727]Open DOISearch in Google Scholar
[36. Yang J, Fan Z, Yang J, Ding J, Yang C, Chen L. MicroRNA-24 Attenuates Neointimal Hyperplasia in the Diabetic Rat Carotid Artery Injury Model by Inhibiting Wnt4 Signaling Pathway. Int J Mol Sci. 2016 Jun;17(6):E765. DOI: 10.3390/ijms17060765. DOI: 10.3390/ijms1706076510.3390/ijms17060765.DOI:10.3390/ijms17060765]Open DOISearch in Google Scholar
[37. Choi YS, Youn HJ, Youn JS, Park CS, Oh YS, Chung WS. Measurement of the intimal thickness of the carotid artery: comparison between 40 MHz ultra-sound and histology in rats. Ultrasound Med Biol. 2009 Jun;35(6):962-6. DOI: 10.1016/j.ultrasmedbio.2008.12.00410.1016/j.ultrasmedbio.2008.12.00419285785]Open DOISearch in Google Scholar
[38. Wajima D, Nakagawa I, Takamura Y, Aketa S, Yonezawa T, Nakase H. Carotid artery stenosis is exacerbated in spontaneously obese model rats with diabetes. J Atheroscler Thromb. 2014 Jul;21(12):1253-9. DOI: 10.5551/jat.2466110.5551/jat.2466125069812]Open DOISearch in Google Scholar
[39. Perez A, Gonzalez-Manzano S, Jimenez R, Perez-Abud R, Haro JM, Osuna A, et al. The flavonoid quercetin induces acute vasodilator effects in healthy volunteers: correlation with beta-glucuronidase activity. Pharmacol Res. 2014 Nov;89:11-8. DOI: 10.1016/j.phrs.2014.07.00510.1016/j.phrs.2014.07.00525076013]Search in Google Scholar
[40. Scridon A, Perian M, Marginean A, Fisca C, Vantu A, Ghertescu D, et al. Wistar rats with long-term streptozotocin-induced type 1 diabetes mellitus replicate the most relevant clinical, biochemical, and hematologic features of human diabetes. Rev Romana Med Lab. 2015;23(3):263-74. DOI: 10.1515/rrlm-2015-002810.1515/rrlm-2015-0028]Open DOISearch in Google Scholar