<abstract xmlns="http://www.w3.org/1999/xhtml"><p><bold>Background</bold>: Fungal infections are a health issue paradoxically fuelled by the developments in medical care. Objectives: Our study is an investigation on the correlation between the infection site and the genotypes of Candida albicans strains isolated from Romanian patients. <bold>Methods</bold>: A total number of 301 isolates from different clinical sites were investigated in terms of genotype determination. <bold>Results</bold>: The isolates were clustered in three groups according to their genotype: 55.81% showed genotype A, 14.62% genotype B, and 29.57% genotype C. <bold>Conclusions</bold>: No significant correlation was found between the genotype and the infection site, but a significant correlation was found between genotype C and isolates from HIV patients proving that C. albicans pathogenicity probably relies on factors related to the host.</p></abstract>

Background: Fungal infections are a health issue paradoxically fuelled by the developments in medical care. Objectives: Our study is an investigation on the correlation between the infection site and the genotypes of Candida albicans strains isolated from Romanian patients. Methods: A total number of 301 isolates from different clinical sites were investigated in terms of genotype determination. Results: The isolates were clustered in three groups according to their genotype: 55.81% showed genotype A, 14.62% genotype B, and 29.57% genotype C. Conclusions: No significant correlation was found between the genotype and the infection site, but a significant correlation was found between genotype C and isolates from HIV patients proving that C. albicans pathogenicity probably relies on factors related to the host.

Genotype comparison of <italic>Candida albicans</italic> isolates from different clinical samples

Gr. T. Popa University of Medicine and Pharmacy

Victor Babes University of Medicine and Pharmacy

Revista Romana de Medicina de Laborator

This work is licensed under the Creative Commons Attribution-NonCommercial-NoDerivatives 3.0 License.

Genotype comparison of  isolates from different clinical samples

Background: Fungal infections are a health issue paradoxically fuelled by the developments in medical care. Objectives: Our study is an investigation on the...

Genotype comparison of Candida albicans isolates from different clinical samples

Pubblicato online: 30 lug 2019

Pagine: 327 - 332

Ricevuto: 22 gen 2019

Accettato: 11 apr 2019

DOI: https://doi.org/10.2478/rrlm-2019-0027

Parole chiave
C. albicans, clinical source, genotype C, HIV-patients, Romania

© 2019 Andra-Cristina Bostănaru et al., published by Sciendo

This work is licensed under the Creative Commons Attribution-NonCommercial-NoDerivatives 3.0 License.

Genotype comparison of Candida albicans isolates from different clinical samples

Pubblicato online: 30 lug 2019

Pagine: 327 - 332

Ricevuto: 22 gen 2019

Accettato: 11 apr 2019

DOI: https://doi.org/10.2478/rrlm-2019-0027

Parole chiaveC. albicans, clinical source, genotype C, HIV-patients, Romania

© 2019 Andra-Cristina Bostănaru et al., published by Sciendo

This work is licensed under the Creative Commons Attribution-NonCommercial-NoDerivatives 3.0 License.

Parole chiave
C. albicans, clinical source, genotype C, HIV-patients, Romania