Plasma phosphorylated neurofilament heavy chains as a potential marker for ischemic stroke patients

1. Glushakova O, Glushakov A, Miller E, Valadka A, Hayes R. Biomarkers for acute diagnosis and management of stroke in neurointensive care units. Brain Circ. 2016;2(1):28. DOI: 10.4103/2394-8108.17854610.4103/2394-8108.178546612624730276272Open DOISearch in Google Scholar

2. Hjalmarsson C, Bjerke M, Andersson B, Blennow K, Zetterberg H, Åberg ND, et al. Neuronal and Glia-Related Biomarkers in Cerebrospinal Fluid of Patients with Acute Ischemic Stroke. J Cent Nerv Syst Dis. 2014;6:51. DOI: 10.4137/JCNSD.S1382110.4137/JCNSD.S13821403929224932109Open DOISearch in Google Scholar

3. Ungureanu D, Iencean ŞM, Dimitriu C, Iencean AŞ, Tascu A. Determination of the phosphorylated neurofilament subunit NF-H (pNF-H) in cerebro-spinal fluid as biomarker in acute traumatic spinal cord injuries. Rev Rom Med Lab. 2014;22(3):377-86.10.2478/rrlm-2014-0029Search in Google Scholar

4. Shaw G. Chapter 21 The Use and Potential of pNF-H as a General Blood Biomarker of Axonal. Brain Neurotrauma Mol Neuropsychol Rehabil Asp. 2015;1-17.Search in Google Scholar

5. Petzold A. Neurofilament phosphoforms: Surrogate markers for axonal injury, degeneration and loss. J Neurol Sci. 2005;233(1):183-98. DOI: 10.1016/j.jns.2005.03.01510.1016/j.jns.2005.03.01515896809Open DOISearch in Google Scholar

6. Clark WM, Rinker LG, Lessov NS, Hazel K, Eckenstein F. Time course of IL-6 expression in experimental CNS ischemia. Neurol Res. 1999;21(3):287-92. DOI: 10.1080/01616412.1999.1174093310.1080/01616412.1999.1174093310319338Open DOISearch in Google Scholar

7. Adams HP, Bendixen BH, Kappelle LJ, Biller J, Love BB, Gordon DL, et al. Classification of subtype of acute ischemic stroke. Definitions for use in a multicenter clinical trial. TOAST. Trial of Org 10172 in Acute Stroke Treatment. Stroke. 1993 ;24(1):35-41. DOI: 10.1161/01.STR.24.1.3510.1161/01.STR.24.1.357678184Open DOISearch in Google Scholar

8. Shibahashi K, Doi T, Tanaka S, Hoda H, Chikuda H, Sawada Y, et al. The Serum Phosphorylated Neurofilament Heavy Subunit as a Predictive Marker for Outcome in Adult Patients after Traumatic Brain Injury. J Neurotrauma. 2016;33(20):1826-33. DOI: 10.1089/neu.2015.423710.1089/neu.2015.423727098610Search in Google Scholar

9. Žurek J, Bartlová L, Fedora M. Hyperphosphorylated neurofilament NF-H as a predictor of mortality after brain injury in children. Brain Inj. 2011;25(2):221-6. DOI: 10.3109/02699052.2010.54189510.3109/02699052.2010.54189521219092Open DOISearch in Google Scholar

10. Cai JY, Lu C, Chen MH, Ba HJ, Chen XD, Lin JH, et al. Predictive value of phosphorylated axonal neurofilament subunit H for clinical outcome in patients with acute intracerebral hemorrhage. Clin Chim Acta. 2013;424:182-6. DOI: 10.1016/j.cca.2013.06.01910.1016/j.cca.2013.06.01923810564Search in Google Scholar

11. Traenka C, Disanto G, Seiffge DJ, Gensicke H, Hert L, Grond-Ginsbach C, et al. Serum Neurofilament Light Chain Levels Are Associated with Clinical Characteristics and Outcome in Patients with Cervical Artery Dissection. Cerebrovasc Dis. 2015;40(5-6):222-7. DOI: 10.1159/00044077410.1159/00044077426418549Open DOISearch in Google Scholar

12. Radwan WM, Rabbah AM, Saber H, Elghonemi MO. A new marker for ischemic cerebrovascular stroke: Phosphorylated Neurofilament H. Egypt J Crit Care Med. 2013;1(2):105-8. DOI: 10.1016/j.ejccm.2013.03.00410.1016/j.ejccm.2013.03.004Search in Google Scholar

13. Singh P, Yan J, Hull R, Read SJ, O’Sullivan J, Henderson RD, et al. Levels of phosphorylated axonal neurofilament subunit H (pNfH) are increased in acute ischemic stroke. J Neurol Sci. 2011;304(1-2):117-21. DOI: 10.1016/j.jns.2011.01.02510.1016/j.jns.2011.01.02521349546Open DOISearch in Google Scholar

14. Kim J-S, Lee K-B, Roh H, Ahn M-Y, Hwang H-W. Gender Differences in the Functional Recovery after Acute Stroke. J Clin Neurol. 2010;6(4):183. DOI: 10.3988/jcn.2010.6.4.18310.3988/jcn.2010.6.4.183302452221264198Open DOISearch in Google Scholar