<abstract xmlns="http://www.w3.org/1999/xhtml"><p> Venous thromboembolism (VTE) is a multifactorial disease; age, a prior history of deep vein thrombosis, cancer, surgery, obesity, prolonged immobility, pregnancy, oral contraceptive agents, thrombophilia, have been identified as major risk factors. Thrombophilia is a heritable or acquired prothrombotic state that increases the tendency to venous thromboembolism. The use of anabolic steroids is strongly linked to venous thromboembolism, due to their role in thrombus formation. We present a case of a venous thromboembolism in a 26-year old male who had undergone a testosterone abuse and had a previously undiagnosed genetic thrombophilia, with discussion upon literature regarding the heritable thrombophilia and prothrombotic effects of testosterone.</p></abstract>

Venous thromboembolism (VTE) is a multifactorial disease; age, a prior history of deep vein thrombosis, cancer, surgery, obesity, prolonged immobility, pregnancy, oral contraceptive agents, thrombophilia, have been identified as major risk factors. Thrombophilia is a heritable or acquired prothrombotic state that increases the tendency to venous thromboembolism. The use of anabolic steroids is strongly linked to venous thromboembolism, due to their role in thrombus formation. We present a case of a venous thromboembolism in a 26-year old male who had undergone a testosterone abuse and had a previously undiagnosed genetic thrombophilia, with discussion upon literature regarding the heritable thrombophilia and prothrombotic effects of testosterone.

Venous thromboembolism caused by testosterone abuse in a young man with previously undiagnosed genetic thrombophilia

Medical Clinic V, University of Medicine and Pharmacy,Târgu Mureş, Romania / Emergency Institute for Cardiovascular Diseases and Transplantation, Cardiology Clinic, Târgu Mureş, Romania

Emergency Institute for Cardiovascular Diseases and Transplantation, Cardiology Clinic, Târgu Mureş, Romania

Revista Romana de Medicina de Laborator

Venous thromboembolism (VTE) is a multifactorial disease; age, a prior history of deep vein thrombosis, cancer, surgery, obesity, prolonged immobility,...

Venous thromboembolism caused by testosterone abuse in a young man with previously undiagnosed genetic thrombophilia

Pubblicato online: 25 mar 2014

Pagine: 63 - 68

DOI: https://doi.org/10.2478/rrlm-2014-0009

Parole chiave
venous thromboembolism, thrombophilia, testosterone

This content is open access.

Venous thromboembolism caused by testosterone abuse in a young man with previously undiagnosed genetic thrombophilia

Pubblicato online: 25 mar 2014

Pagine: 63 - 68

DOI: https://doi.org/10.2478/rrlm-2014-0009

Parole chiavevenous thromboembolism, thrombophilia, testosterone

This content is open access.

Parole chiave
venous thromboembolism, thrombophilia, testosterone