Age-dependent myocardial transcriptomic changes in the rat. Novel insights into atrial and ventricular arrhythmias pathogenesis

1. Chow GV, Marine JE, Fleg JL. Epidemiology of arrhythmias and conduction disorders in older adults. Clin Geriatr Med. 2012 Nov;28(4):539-53. DOI: 10.1016/j. cger.2012.07.003Search in Google Scholar

2. Mirza M, Strunets A, Shen WK, Jahangir A. Mechanisms of arrhythmias and conduction disorders in older adults. Clin Geriatr Med. 2012 Nov;28(4):555-73. DOI: 10.1016/j.cger.2012.08.00510.1016/j.cger.2012.08.005Search in Google Scholar

3. Brembilla-Perrot B. Age-related changes in arrhythmias and electrophysiologic properties. Card Electrophysiol Rev. 2003 Jan;7(1):88-91. DOI: 10.1023/A:102361172794710.1023/A:1023611727947Search in Google Scholar

4. Sohal RS, Weindruch R. Oxidative stress, caloric restriction, and aging. Science. 1996 Jul;273:59-63. DOI: 10.1126/science.273.5271.5910.1126/science.273.5271.59Search in Google Scholar

5. Ramsey JJ, Harper ME, Weindruch R. Restriction of energy intake, energy expenditure, and aging. Free Radic Biol Med. 2000 Nov;29:946-68. DOI: 10.1016/ S0891-5849(00)00417-210.1016/S0891-5849(00)00417-2Search in Google Scholar

6. Golden TR, Hinerfeld DA, Melov S. Oxidative stress and aging: beyond correlation. Aging Cell. 2002 Dec;1:117-23. DOI: 10.1046/j.1474-9728.2002.00015.x10.1046/j.1474-9728.2002.00015.xSearch in Google Scholar

7. Gavrilov LA, Gavrilova NS. Evolutionary theories of aging and longevity. Sci World J. 2002 Feb;2:339-56. DOI: 10.1100/tsw.2002.9610.1100/tsw.2002.96Search in Google Scholar

8. Volkova M, Garg R, Dick S, Boheler KR. Aging-associated changes in cardiac gene expression. Cardiovasc Res. 2005 May;66(2):194-204. DOI: 10.1016/j.cardiores. 2004.11.016Search in Google Scholar

9. Gaborit N, Wichter T, Varro A, Szuts V, Lamirault G, Eckardt L, et al. Transcriptional profiling of ion channel genes in Brugada syndrome and other right ventricular arrhythmogenic diseases. Eur Heart J. 2009 Feb;30(4):487-96. DOI: 10.1093/eurheartj/ehn52010.1093/eurheartj/ehn520Search in Google Scholar

10. Boheler KR, Volkova M, Morrell C, Garg R, Zhu Y, Margulies K, et al. Sex- and age-dependent human transcriptome variability: Implications for chronic heart failure. Proc Natl Acad Sci U S A. 2003 Mar; 100(5):2754-9. DOI: 10.1073/pnas.043656410010.1073/pnas.0436564100Search in Google Scholar

11. Melov S, Coskun PE, Wallace DC. Mouse models of mitochondrial disease, oxidative stress, and senescence. Mutat Res. 1999 Jul;434: 233-42. DOI: 10.1016/ S0921-8777(99)00031-210.1016/S0921-8777(99)00031-2Search in Google Scholar

12. Liang H, Masoro EJ, Nelson JF, Strong R, McMahan CA, Richardson A. Genetic mouse models of extended lifespan. Exp Gerontol. 2003 Nov-Dec;38:1353-64. DOI: 10.1016/j.exger.2003.10.01910.1016/j.exger.2003.10.01914698816Search in Google Scholar

13. Jazwinski SM. Aging and longevity genes. Acta Biochim Pol. 2000;47:269-79.10.18388/abp.2000_4007Search in Google Scholar

14. Fuster V, Ryden LE, Cannom DS, Crijns HJ, Curtis AB, Ellenbogen KA, et al. 2011 ACCF/AHA/HRS focused updates incorporated into the ACC/AHA/ ESC 2006 guidelines for the management of patients with atrial fibrillation: A report of the American College of Cardiology Foundation/American Heart Association task force on practice guidelines. Circulation. 2011 Mar;123:e269-36713. DOI: 10.1161/ CIR.0b013e318214876d10.1161/CIR.0b013e318214876d21382897Search in Google Scholar

15. Roger VL, Go AS, Lloyd-Jones DM, Benjamin EJ,Berry JD,Borden WB, et al. Executive summary: heart disease and stroke statistics-2012 update: a report from the American Heart Association. Circulation. 2012 Jan;125(1):188-97. DOI: 10.1161/ CIR.0b013e3182456d46Search in Google Scholar

16. Miyasaka Y, Barnes ME, Gersh BJ, Cha SS, Bailey KR, Abhayaratna WP, et al. Secular trends in incidence of atrial fibrillation in Olmsted County, Minnesota, 1980 to 2000, and implications on the projections for future prevalence. Circulation. 2006 Jul;114:119-25. DOI: 10.1161/CIRCULATIONAHA.105.59514010.1161/CIRCULATIONAHA.105.59514016818816Search in Google Scholar

17. Mozaffarian D, Furberg CD, Psaty BM, Siscovick D. Physical activity and incidence of atrial fibrillation in older adults: the cardiovascular health study. Circulation. 2008 Aug;118:800-7. DOI: 10.1161/CIRCULATIONAHA. 108.785626Search in Google Scholar

18. Wakili R, Voigt N, Kääb S, Dobrev D, Nattel S. Recent advances in the molecular pathophysiology of atrial fibrillation. J Clin Invest. 2011 Aug;121(8):2955-68. DOI: 10.1172/JCI4631510.1172/JCI46315314873921804195Search in Google Scholar

19. Nattel S, Li D, Yue L. Basic mechanisms of atrial fibrillation: very new insights into very old ideas. Annu Rev Physiol. 2000;62:51-77. DOI: 10.1146/annurev.physiol. 62.1.51Search in Google Scholar

20. Yamada M, Ohta K, Niwa A, Tsujino N, Nakada T, Hirose M. Contribution of L-type Ca2+ channels to early afterdepolarizations induced by I Kr and I Ks channel suppression in guinea pig ventricular myocytes. J Membr Biol. 2008 Apr;222(3):151-66. DOI: 10.1007/ s00232-008-9113-910.1007/s00232-008-9113-918566732Search in Google Scholar

21. Van Wagoner DR, Pond AL, Lamorgese M, Rossie SS, McCarthy PM, Nerbonne JM. Atrial L-Type Ca2+ currents and human atrial fibrillation. Circ Res. 1999 Sep;85:428-36. DOI: 10.1161/01.RES.85.5.42810.1161/01.RES.85.5.42810473672Search in Google Scholar

22. Gaspo R, Bosch RF, Bou-Abboud E, Nattel S. Tachycardia- induced changes in Na+ current in a chronic dog model of atrial fibrillation. Circ Res. 1997 Dec;81:1045-52. DOI: 10.1161/01.RES.81.6.104510.1161/01.RES.81.6.10459400386Search in Google Scholar

23. Makiyama T, Akao M, Shizuta S, Doi T, Nishiyama K, Oka Y, et al. A novel SCN5A gain-of-function mutation M1875T associated with familial atrial fibrillation. J Am Coll Cardiol. 2008 Oct;52(16):1326-34. DOI: 10.1016/j.jacc.2008.07.01310.1016/j.jacc.2008.07.01318929244Search in Google Scholar

24. Olesen MS, Refsgaard L, Holst AG, Larsen AP, Grubb S, Haunsø S, et al. A novel KCND3 gain-of-function mutation associated with early-onset of persistent lone atrial fibrillation. Cardiovasc Res. 2013 Jun;98(3):488-95. DOI: 10.1093/cvr/cvt02810.1093/cvr/cvt02823400760Search in Google Scholar

25. Olson TM, Alekseev AE, Moreau C, Liu XK, Zingman LV, Miki T, et al. KATP channel mutation confers risk for vein of Marshall adrenergic atrial fibrillation. Nat Clin Pract Cardiovasc Med. 2007 Feb;4(2):110-6. DOI: 10.1038/ncpcardio079210.1038/ncpcardio0792201330617245405Search in Google Scholar

26. Limberg SH, Netter MF, Rolfes C, Rinné S, Schlichthörl G, Zuzarte M, et al. TASK-1 channels may modulate action potential duration of human atrial cardiomyocytes. Cell Physiol Biochem. 2011;28(4):613-24. DOI: 10.1159/00033575710.1159/000335757370918322178873Search in Google Scholar

27. Frustaci A, Chimenti C, Bellocci F, Morgante E, Russo MA, Maseri A. Histological substrate of atrial biopsies in patients with lone atrial fibrillation. Circulation. 1997 Aug;96(4):1180-4. DOI: 10.1161/01.CIR.96.4.118010.1161/01.CIR.96.4.11809286947Search in Google Scholar

28. Scridon A, Gallet C, Arisha MM, Oréa V, Chapuis B, Li N, et al. Unprovoked atrial tachyarrhythmias in aging spontaneously hypertensive rats: The role of the autonomic nervous system. Am J Physiol Heart Circ Physiol. 2012 Aug;303(3):H386-92. DOI: 10.1152/ ajpheart.00004.201210.1152/ajpheart.00004.201222661510Search in Google Scholar

29. Lai LP, Su MJ, Lin JL, Tsai CH, Lin FY, Chen YS, et al. Measurement of funny current (I(f)) channel mRNA in human atrial tissue: Correlation with left atrial filling pressure and atrial fibrillation. J Cardiovasc Electrophysiol. 1999 Jul;10:947-53. DOI: 10.1111/j.1540-8167.1999.tb01265.x10.1111/j.1540-8167.1999.tb01265.x10413374Search in Google Scholar

30. Morel E,Meyronet D, Thivolet-Bejuy F, Chevalier P. Identification and distribution of interstitial Cajal cells in human pulmonary veins. Heart Rhythm. 2008 Jul;5:1063-7. DOI: 10.1016/j.hrthm.2008.03.05710.1016/j.hrthm.2008.03.05718598966Search in Google Scholar

31. Suenari K, Cheng CC, Chen YC, Lin YK, Nakano Y, Kihara Y, et al. Effects of Ivabradine on the pulmonary vein electrical activity and modulation of pacemaker currents and calcium homeostasis. J Cardiovasc Electrophysiol. 2012 Feb;23(2):200-6. DOI: 10.1111/j.1540-8167.2011.02173.x10.1111/j.1540-8167.2011.02173.x21914029Search in Google Scholar

32. Li Y, Huang Y, Li Z, Wang H, Song J, Liu Y, et al. Effect of ivabradine on hyperpolarization activated cation current in canine pulmonary vein sleeve cardiomyocytes with atrial fibrillation J Geriatr Cardiol. 2008;5(1):39-42.Search in Google Scholar

33. Xue X, Yan GX. The funny current (If): is it a novel antiarrhythmic target to treat atrial fibrillation? J Cardiovasc Electrophysiol. 2012 Feb;23(2):207-8. DOI: 10.1111/j.1540-8167.2011.02209.x 10.1111/j.1540-8167.2011.02209.x22050077Search in Google Scholar