Infant acute leukemia with lineage switch at relapse expressing a novel t(4;11)(q21;q23) MLL-AF4 fusion transcript

1. De Braekeleer E, Douet-Guilbert N, Le Bris MJ, Basinko A, Morel F, De Braekeleer M. Gene expression profiling of adult t(4;11)(q21;q23)-associated acute lymphoblastic leukemia reveals a different signature from pediatric cases. Anticancer Res. 2012 Sep;32(9):3893-9Search in Google Scholar

2. De Braekeleer M, Morel F, Le Bris MJ, Herry A, Douet-Guilbert N. The MLL gene and translocations involving chromosomal band 11q23 in acute leukemia. Anticancer Res. 2005 May-Jun;25(3B):1931-44Search in Google Scholar

3. Drexler HG, Quentmeier H, MacLeod RA. Malignant hematopoietic cell lines: in vitro models for the study of MLL gene alterations. Leukemia. 2004 Feb;18(2):227-3210.1038/sj.leu.2403236Search in Google Scholar

4. Super HG, Strissel PL, Sobulo OM, Burian D, Reshmi SC, Roe B, Zeleznik-Le NJ, et al. Identification of complex genomic breakpoint junctions in thet(9;11) MLL-AF9 fusion gene in acute leukemia. Genes Chromosomes Cancer. 1997 Oct;20(2):185-9510.1002/(SICI)1098-2264(199710)20:2<185::AID-GCC9>3.0.CO;2-#Search in Google Scholar

5. Pui CH, Evans WE. Acute lymphoblastic leukemia. N Engl J Med. 1998 Aug 27;339(9):605-1510.1056/NEJM199808273390907Search in Google Scholar

6. Pui CH, Kane JR, Crist WM. Biology and treatment of infant leukemias. Leukemia. 1995 May;9(5):762-9Search in Google Scholar

7. Ludwig W D, Rieder H, Bartram C R, Heinze B, Schwartz S, Gassmann W, et al. Immunophenotypic and genotypic features, clinical characteristics and treatment outcome of adult pro-B acute lymphoblastic leukemia: results of the German multicenter trials GMALL03/87 and 04/89. Blood 1998; 92:1898-1909Search in Google Scholar

8. van Dongen JJ, Macintyre EA, Gabert JA, Delabesse E, Rossi V, Saglio G, et al. Standardized RT-PCR analysis of fusion gene transcripts from chromosome aberrations in acute leukemia for detection of minimal residual disease. Report of the BIOMED-1 Concerted Action: investigation of minimal residual disease in acute leukemia. Leukemia. 1999 Dec;13(12):1901-2810.1038/sj.leu.2401592Search in Google Scholar

9. Felix CA, Hosler MR, Slater DJ, Parker RI, Masterson M, Whitlock JA, et al. MLL genomic breakpoint distribu- tion within the breakpoint cluster region in de novo leukemia in children. J Pediatr Hematol Oncol. 1998 Jul- Aug;20(4):299-30810.1097/00043426-199807000-00004Search in Google Scholar

10. Reichel M, Gillert E, Angermüller S, Hensel JP, Heidel F, Lode M, et al. Biased distribution of chromosomal breakpoints involving the MLL gene in infants versus children and adults with t(4;11) ALL. Oncogene. 2001 May 24;20(23):2900-710.1038/sj.onc.1204401Search in Google Scholar

11. Muñoz L, Nomdedéu JF, Villamor N, Guardia R, Colomer D, Ribera JM, et al. Acute myeloid leukemia with MLL rearrangements: clinicobiological features, prognostic impact and value of flow cytometry in the detection of residual leukemic cells. Leukemia. 2003 Jan;17(1):76-8210.1038/sj.leu.2402708Search in Google Scholar

12. Marcucci G, Strout MP, Bloomfield CD, Caligiuri MA. Detection of unique ALL1 (MLL) fusion transcripts in normal human bone marrow and blood: distinct origin of normal versus leukemic ALL1 fusion transcripts. Cancer Res. 1998 Feb 15;58(4):790-3Search in Google Scholar

13. Jansen MW, Corral L, van der Velden VH, Panzer- Grümayer R, Schrappe M, Schrauder A, et al. Immunobiological diversity in infant acute lymphoblastic leukemia is related to the occurrence and type of MLL gene rearrangement. Leukemia. 2007 Apr;21(4):633-4110.1038/sj.leu.2404578Search in Google Scholar

14. Hagemeijer A, van Dongen JJ, Slater RM, van't Veer MB, Behrendt H, Hählen K, et al. Characterization of the blast cells in acute leukemia with translocation (4;11): report of eight additional cases and of one case with a variant translocation. Leukemia. 1987 Jan;1(1):24-3Search in Google Scholar

15. Gleissner B, Goekbuget N, Rieder H, Arnold R, Schwartz S, Diedrich H, et al. CD10- pre-B acute lymphoblastic leukemia (ALL) is a distinct high-risk subgroup of adult ALL associated with a high frequency of MLL aberrations: results of the German Multicenter Trials for Adult ALL (GMALL). Blood. 2005 Dec 15;106(13):4054-610.1182/blood-2005-05-1866Search in Google Scholar

16. Abdelhaleem M. Frequent but nonrandom expression of myeloid markers on de novo childhood acute lymphoblastic leukemia. Exp Mol Pathol. 2007 Aug;83(1):138-4110.1016/j.yexmp.2007.02.004Search in Google Scholar

17. Supriyadi E, Veerman AJ, Sutaryo, Purwanto I, Vd Ven PM, Cloos J. Myeloid Antigen Expression in Childhood Acute Lymphoblastic Leukemia and Its Relevance for Clinical Outcome in Indonesian ALL-2006 Protocol. J Oncol. 2012;2012:13518610.1155/2012/135186351375223227046Search in Google Scholar

18. Griesinger F, Elfers H, Ludwig WD, Falk M, Rieder H, Harbott J, et al. Detection of HRX-FEL fusion transcripts in pre-pre-B-ALL with and without cytogenetic demonstration of t(4;11). Leukemia. 1994 Apr;8(4):542-8Search in Google Scholar

19. Behm FG, Smith FO, Raimondi SC, Pui CH, Bernstein ID. Human homologue of the rat chondroitin sulfate proteoglycan, NG2, detected by monoclonal antibody 7.1, identifies childhood acute lymphoblastic leukemias with t(4;11)(q21;q23) or t(11;19)(q23;p13) and MLL gene rearrangements. Blood. 1996 Feb 1;87(3):1134-910.1182/blood.V87.3.1134.bloodjournal8731134Search in Google Scholar

20. Borowitz MJ, Béné M-C, Harris NL, Porwit A, Matutes E. Acute leukaemias of ambiguous lineage. In: Swerdlow SH, Campo E, Harris NL, Jaffe ES, Pileri SA, Stein H, et al., editors. WHO classification of tumours of haematopoietic and lymphoid tissues. Lyon: WHO Press; 2008. p. 150-5Search in Google Scholar

21. Béné MC, Porwit A. Acute leukemias of ambiguous lineage. Semin Diagn Pathol. 2012 Feb;29(1):12-810.1053/j.semdp.2011.08.00422372202Search in Google Scholar

22. Béné MC, Castoldi G, Knapp W, Ludwig WD, Matutes E, Orfao A, et al. Proposals for the immunological classification of acute leukemias. European Group for the Immunological Characterization of Leukemias (EGIL). Leukemia 1995;9:1783-6Search in Google Scholar

23. Catovsky D, Matutes E, Buccheri V, Shetty V, Hanslip J, Yoshida N, et al. A classification of acute leukaemia for the 1990s. Ann Hematol 1991;62:16-2110.1007/BF017149782031964Search in Google Scholar

24. Chen CS, Sorensen PH, Domer PH, Reaman GH, Korsmeyer SJ, Heerema NA, et al. Molecular rearrangements on chromosome 11q23 predominate in infant acute lymphoblastic leukemia and are associated with specific biologic variables and poor outcome. Blood. 1993 May 1;81(9):2386-9310.1182/blood.V81.9.2386.bloodjournal8192386Search in Google Scholar

25. Rubnitz JE, Link MP, Shuster JJ, Carroll AJ, Hakami N, Frankel LS, et al. Frequency and prognostic significance of HRX rearrangements in infant acute lymphoblastic leukemia: a Pediatric Oncology Group study. Blood. 1994 Jul 15;84(2):570-310.1182/blood.V84.2.570.570Search in Google Scholar

26. van der Linden MH, Creemers S, Pieters R. Diagnosis and management of neonatal leukaemia. Semin Fetal Neonatal Med. 2012 Aug;17(4):192-510.1016/j.siny.2012.03.00322510298Search in Google Scholar

27. Zhang Y, Wu D, Sun A, Qiu H, He G, Jin Z, et al. Clinical characteristics, biological profile, and outcome of biphenotypic acute leukemia: a case series. Acta Haematol. 2011;125(4):210-810.1159/00032259421266800Search in Google Scholar

28. Hughes TP, Morgan GJ, Martiat P, Goldman JM. Detection of residual leukemia after bone marrow transplant for chronic myeloid leukemia: role of polymerase chain reaction in predicting relapse. Blood. 1991;77(4):874-810.1182/blood.V77.4.874.874Search in Google Scholar

29. Gabert J, Beillard E, van der Velden VH, Bi W, Grimwade D, Pallisgaard N, et al. Standardization and quality control studies of 'real-time' quantitative reverse transcriptase polymerase chain reaction of fusion gene transcripts for residual disease detection in leukemia - a Europe Against Cancer program. Leukemia. 2003 Dec;17(12):2318-5710.1038/sj.leu.240313514562125Search in Google Scholar

30. Gerr H, Zimmermann M, Schrappe M, Dworzak M, Ludwig WD, Bradtke J, et al. Acute leukaemias of ambiguous lineage in children: characterization, prognosis and therapy recommendations. Br J Haematol. 2010 Apr;149(1):84-9210.1111/j.1365-2141.2009.08058.x20085575Search in Google Scholar

31. Sakaki H, Kanegane H, Nomura K, Goi K, Sugita K, Miura M, Ishii E, Miyawaki T. Early lineage switch in an infant acute lymphoblastic leukemia. Int J Hematol 2009; 90: 653-510.1007/s12185-009-0446-719936875Search in Google Scholar

32. Stasik C, Ganguly S, Cunningham MT, Hagemeister S, Persons DL. Infant acute lymphoblastic leukemia with t(11;16)(q23;p13.3) and lineage switch into acute monoblastic leukemia. Cancer Genet Cytogenet 2006; 168: 146-9 10.1016/j.cancergencyto.2006.02.01316843104Search in Google Scholar

33. Jiang JG, Roman E, Nandula SV, Murty VV, Bhagat G, Alobeid B. Congenital MLL-positive B-cell acute lymphoblastic leukemia (B-ALL) switched lineage at relapse to acute myelocytic leukemia (AML) with persistent t(4;11) and t(1;6) translocations and JH gene rearrangement. Leuk Lymphoma 2005; 46: 1223-710.1080/1042819050008605516085566Search in Google Scholar

34. Park M, Koh KN, Kim BE, Im HJ, Jang S, Park CJ, Chi HS, Seo JJ. Lineage switch at relapse of childhood acute leukemia: a report of four cases. J Korean Med Sci. 2011 Jun;26(6):829-3110.3346/jkms.2011.26.6.829310288021655072Search in Google Scholar

35. Lou Z, Zhang CC, Tirado CA, Slone T, Zheng J, Zaremba CM, Oliver D, Chen W. Infantile mixed phenotype acute leukemia (bilineal and biphenotypic) with t(10;11) (p12;q23);MLL-MLLT10. Leuk Res. 2010 Aug;34(8):1107-9 10.1016/j.leukres.2010.02.02920299091Search in Google Scholar