<abstract xmlns="http://www.w3.org/1999/xhtml"><bold>BACKGROUND.</bold> The malignant sinonasal tumour is very rare. Sinonasal adenocarcinoma comprises only 10-20% of all primary malignant sinonasal tumours. The commonest type is the maxillary squamous cell carcinoma. It commonly presents with nasal blockage, nasal discharge and epistaxis during the early stage. Headache and blurry vision may occur at an advanced stage when it has invaded the brain, the eye or the optic nerve.<bold>CASE REPORT.</bold> We present a 63-year-old patient with acute progressive worsening unilateral blurry vision and headache for 1 month. Epistaxis with anosmia developed only later. The patient had a neuroimaging by both Computed Tomography (CT) scan and Magnetic Resonance Imaging (MRI) scan which showed a skull base tumour, but early biopsy was inconclusive. He underwent combined transcranial and transsphenoidal tumor debulking in view of clinical impression of olfactory neuroblastoma. The histopathological examination showed adenocarcinoma. He was sent for postoperative radiotherapy.<bold>CONCLUSION.</bold> We highlighted that a patient with sinonasal adenocarcinoma may present initially with the symptom of invasion to neighbouring structures prior to the local symptom.</abstract>

BACKGROUND. The malignant sinonasal tumour is very rare. Sinonasal adenocarcinoma comprises only 10-20% of all primary malignant sinonasal tumours. The commonest type is the maxillary squamous cell carcinoma. It commonly presents with nasal blockage, nasal discharge and epistaxis during the early stage. Headache and blurry vision may occur at an advanced stage when it has invaded the brain, the eye or the optic nerve.CASE REPORT. We present a 63-year-old patient with acute progressive worsening unilateral blurry vision and headache for 1 month. Epistaxis with anosmia developed only later. The patient had a neuroimaging by both Computed Tomography (CT) scan and Magnetic Resonance Imaging (MRI) scan which showed a skull base tumour, but early biopsy was inconclusive. He underwent combined transcranial and transsphenoidal tumor debulking in view of clinical impression of olfactory neuroblastoma. The histopathological examination showed adenocarcinoma. He was sent for postoperative radiotherapy.CONCLUSION. We highlighted that a patient with sinonasal adenocarcinoma may present initially with the symptom of invasion to neighbouring structures prior to the local symptom.

Sinonasal adenocarcinoma with aggressive ocular symptom

Romanian Journal of Rhinology

This work is licensed under the Creative Commons Attribution-NonCommercial-NoDerivatives 4.0 License.

{"article-title":"Sinonasal adenocarcinoma with aggressive ocular symptom"}

BACKGROUND. The malignant sinonasal tumour is very rare. Sinonasal adenocarcinoma comprises only 10-20% of all primary malignant sinonasal tumours. The...

Sinonasal adenocarcinoma with aggressive ocular symptom

Pubblicato online: 07 mar 2019

Pagine: 49 - 51

Ricevuto: 15 ott 2018

Accettato: 26 nov 2018

DOI: https://doi.org/10.2478/rjr-2019-0007

Parole chiave
sinonasal tumour, adenocarcinoma, ocular symptom, intracranial spread

© 2019 Nadia Syafeera Naserrudin et al., published by Sciendo

This work is licensed under the Creative Commons Attribution-NonCommercial-NoDerivatives 4.0 License.

Sinonasal adenocarcinoma with aggressive ocular symptom

Pubblicato online: 07 mar 2019

Pagine: 49 - 51

Ricevuto: 15 ott 2018

Accettato: 26 nov 2018

DOI: https://doi.org/10.2478/rjr-2019-0007

Parole chiavesinonasal tumour, adenocarcinoma, ocular symptom, intracranial spread

© 2019 Nadia Syafeera Naserrudin et al., published by Sciendo

This work is licensed under the Creative Commons Attribution-NonCommercial-NoDerivatives 4.0 License.

Parole chiave
sinonasal tumour, adenocarcinoma, ocular symptom, intracranial spread