<abstract xmlns="http://www.w3.org/1999/xhtml">

<p>Patient-prosthesis mismatch (PPM) is the situation in which the area of an artificial valve is smaller than that of a healthy native valve it replaces. By this definition, all artificial valves demonstrate PPM, but large observational studies and several meta-analyses suggest that it is present in 30-50% of patients after surgical aortic valve replacement (SAVR). PPM has an impact on outcomes only when the indexed aortic valve area (AVAi) is ≤0.85cm2/m2 (moderate PPM) or 0.65cm2/m2 (severe PPM), particularly in patients with reduced LVEF. In transcatheter aortic valve replacement, the prevalence of PPM may be as low as 0.1%, and its impact on hard outcomes is not clear. We present a review of the relevant literature together with a framework for the differential diagnosis of increased pressure gradient and reduced area in prosthetic aortic valves and different strategies to reduce the risk of PPM with SAVR.</p>
</abstract>

Patient-prosthesis mismatch (PPM) is the situation in which the area of an artificial valve is smaller than that of a healthy native valve it replaces. By this definition, all artificial valves demonstrate PPM, but large observational studies and several meta-analyses suggest that it is present in 30-50% of patients after surgical aortic valve replacement (SAVR). PPM has an impact on outcomes only when the indexed aortic valve area (AVAi) is ≤0.85cm2/m2 (moderate PPM) or 0.65cm2/m2 (severe PPM), particularly in patients with reduced LVEF. In transcatheter aortic valve replacement, the prevalence of PPM may be as low as 0.1%, and its impact on hard outcomes is not clear. We present a review of the relevant literature together with a framework for the differential diagnosis of increased pressure gradient and reduced area in prosthetic aortic valves and different strategies to reduce the risk of PPM with SAVR.

Aortic patient-prosthesis mismatch - does it matter? A review for cardiologists and cardiac surgeons

Romanian Journal of Cardiology

This work is licensed under the Creative Commons Attribution 4.0 International License.

Patient-prosthesis mismatch (PPM) is the situation in which the area of an artificial valve is smaller than that of a healthy native valve it replaces. By this...

Aortic patient-prosthesis mismatch - does it matter? A review for cardiologists and cardiac surgeons

Article Category: Review

Pubblicato online: 05 mar 2024

Pagine: -

DOI: https://doi.org/10.2478/rjc-2024-0001

Parole chiave
patient-prosthesis mismatch, aortic valve disease, aortic valve replacement

© 2024 Alexandru C Visan et al., published by Sciendo

This work is licensed under the Creative Commons Attribution 4.0 International License.

Aortic patient-prosthesis mismatch - does it matter? A review for cardiologists and cardiac surgeons

Article Category: Review

Pubblicato online: 05 mar 2024

Pagine: -

DOI: https://doi.org/10.2478/rjc-2024-0001

Parole chiavepatient-prosthesis mismatch, aortic valve disease, aortic valve replacement

© 2024 Alexandru C Visan et al., published by Sciendo

This work is licensed under the Creative Commons Attribution 4.0 International License.

Parole chiave
patient-prosthesis mismatch, aortic valve disease, aortic valve replacement