<abstract xmlns="http://www.w3.org/1999/xhtml"><sec id="j_rjaic-2020-0017_s_007_w2aab3b7c14b1b6b1aab1c15b1Aa"><h3>Clinical background</h3><p>Volatile anaesthetics (VAs) have been shown to protect cardiomyocytes against ischaemia and reperfusion injury in cardiac surgery.</p></sec><sec id="j_rjaic-2020-0017_s_008_w2aab3b7c14b1b6b1aab1c15b2Aa"><h3>Clinical problems</h3><p>VAs have been shown in multiple trials and meta-analyses to be associated with better outcomes when compared to intravenous anaesthesia in cardiac surgery. However, recent data from a large randomised controlled trial do not confirm the superiority of VA as compared to total intravenous anaesthesia in this population.</p></sec><sec id="j_rjaic-2020-0017_s_009_w2aab3b7c14b1b6b1aab1c15b3Aa"><h3>Review objectives</h3><p>This mini review presents the VA cardioprotective effects, their clinical use in cardiac surgery and the most recent evidence that compares VA to intravenous anaesthesia for reducing perioperative morbidity. At present, there is no clear superiority of VA over intravenous anaesthesia in improving the outcome after cardiac surgery.</p></sec></abstract>

Clinical backgroundVolatile anaesthetics (VAs) have been shown to protect cardiomyocytes against ischaemia and reperfusion injury in cardiac surgery.Clinical problemsVAs have been shown in multiple trials and meta-analyses to be associated with better outcomes when compared to intravenous anaesthesia in cardiac surgery. However, recent data from a large randomised controlled trial do not confirm the superiority of VA as compared to total intravenous anaesthesia in this population.Review objectivesThis mini review presents the VA cardioprotective effects, their clinical use in cardiac surgery and the most recent evidence that compares VA to intravenous anaesthesia for reducing perioperative morbidity. At present, there is no clear superiority of VA over intravenous anaesthesia in improving the outcome after cardiac surgery.

Role of anaesthetic choice in improving outcome after cardiac surgery

Romanian Journal of Anaesthesia and Intensive Care

This work is licensed under the Creative Commons Attribution 4.0 International License.

{"article-title":"Role of anaesthetic choice in improving outcome after cardiac surgery"}

Clinical backgroundVolatile anaesthetics (VAs) have been shown to protect cardiomyocytes against ischaemia and reperfusion injury in cardiac surgery.Clinical...

Role of anaesthetic choice in improving outcome after cardiac surgery

Article Category: Original Paper

Pubblicato online: 31 dic 2020

Pagine: 37 - 42

Ricevuto: 26 mag 2020

Accettato: 07 ago 2020

DOI: https://doi.org/10.2478/rjaic-2020-0017

Parole chiave
cardiac anaesthesia, cardiac surgery, total intravenous anaesthesia, volatile anaesthetics, anaesthetic preconditioning, myocardial ischaemia

© 2020 Mihai Stefan, Daniela Filipescu. published by Sciendo

This work is licensed under the Creative Commons Attribution 4.0 International License.

Role of anaesthetic choice in improving outcome after cardiac surgery

Article Category: Original Paper

Pubblicato online: 31 dic 2020

Pagine: 37 - 42

Ricevuto: 26 mag 2020

Accettato: 07 ago 2020

DOI: https://doi.org/10.2478/rjaic-2020-0017

Parole chiavecardiac anaesthesia, cardiac surgery, total intravenous anaesthesia, volatile anaesthetics, anaesthetic preconditioning, myocardial ischaemia

© 2020 Mihai Stefan, Daniela Filipescu. published by Sciendo

This work is licensed under the Creative Commons Attribution 4.0 International License.

Parole chiave
cardiac anaesthesia, cardiac surgery, total intravenous anaesthesia, volatile anaesthetics, anaesthetic preconditioning, myocardial ischaemia