Sedation (1, awake; 2, medium sedation/wakes up easily; 3, mostly sedated does not wake up easily; 4, unarousable) |
1st hour (1/2/3) | 3 (14.29%)/14 (66.67%)/4 (19.05%) | 1 (4.76%)/13 (61.9%)/7 (33.33%) | 0.408 |
2nd hour (1/2/3) | 3 (14.29%)/15 (71.43%)/3 (14.29%) | 4 (19.05%)/12 (57.14%)/5 (23.81%) | 0.671 |
4th hour (1/2/3) | 5 (23.81%)/15 (71.43%)/1 (4.76%) | 7 (33.33%)/12 (57.14%)/2 (9.52%) | 0.616 |
6th hour (1/2) | 12 (57.14%)/9 (42.86%) | 12 (57.14%)/9 (42.86%) | 0.999 |
12th hour (1/2) | 16 (76.19%)/5 (23.81%) | 13 (61.9%)/8 (38.1%) | 0.505 |
18th hour (1/2) | 16 (76.19%)/5 (23.81%) | 17 (80.95%)/4 (19.05%) | 0.999 |
24th hour (1/2) | 18 (85.71%)/3 (14.29%) | 18 (85.71%)/3 (14.29%) | 0.999 |
36th hour (1/2) | 18 (85.71%)/3 (14.29%) | 19 (90.48%)/2 (9.52%) | 0.999 |
48th hour (1/2/3) | 20 (95.24%)/1 (4.76%)/− | 18 (85.71%)/2 (9.52%)/1 (4.76%) | 0.606 |
PONV (0, none; 1, nausea; 2, less than three episodes of vomiting; 3: more than three episodes of vomiting) |
1st day (0/1/2) | 17 (80.95%)/2 (9.52%)/2 (9.52%) | 17 (80.95%)/2 (9.52%)/2 (9.52%) | 0.999 |
2nd day (0/2) | 19 (90.48%)/2 (9.52%) | 18 (85.71%)/3 (14.29%) | 0.999 |
Other side effects |
Pruritus (no/yes) | 19 (90.48%)/2 (9.52%) | 18 (85.71%)/3 (14.29%) | 0.999 |
Hallucinations (no/yes) | 15 (71.43%)/6 (28.57%) | 20 (95.24%)/1 (4.76%) | 0.093 |
Confusion (no/yes) | 19 (90.48%)/2 (9.52%) | 21 (100%)/− | 0.488 |
Seizures (no/yes) | 21 (100%)/− | 21 (100%)/− | - |
Dry mouth (no/yes) | 12 (57.14%)/9 (42.86%) | 19 (90.48%)/2 (9.52%) | 0.032 |
Bradycardia (no/yes) | 21 (100%)/− | 21 (100%)/− | - |
Uterine retention (no/yes) | 21 (100%)/− | 21 (100%)/− | - |
Hypotension (no/yes) | 21 (100%)/− | 20 (95.24%)/1 (4.76%) | 0.999 |