Laser speckle contrast imaging of perfusion in oncological clinical applications: a literature review
Categoria dell'articolo: Review
Pubblicato online: 15 set 2024
Pagine: 326 - 334
Ricevuto: 16 lug 2024
Accettato: 26 lug 2024
DOI: https://doi.org/10.2478/raon-2024-0042
Parole chiave
© 2024 Rok Hren et al., published by Sciendo
This work is licensed under the Creative Commons Attribution 4.0 International License.
Background
Laser speckle coherence imaging (LSCI) is an emerging imaging modality that enables noninvasive visualization and assessment of tissue perfusion and microcirculation. In this article, we evaluated LSCI in imaging perfusion in clinical oncology through a systematic review of the literature.
Methods
The inclusion criterion for the literature search in PubMed, Web of Science and Scopus electronic databases was the use of LSCI in clinical oncology, meaning that all animal, phantom,
Results
Thirty-six articles met the inclusion criteria. The anatomic locations of the neoplasms in the selected articles were brain (5 articles), breasts (2 articles), endocrine glands (4 articles), skin (12 articles), and the gastrointestinal tract (13 articles).
Conclusions
While LSCI is emerging as an appealing imaging modality, it is crucial for more clinical sites to initiate clinical trials. A lack of standardized protocols and interpretation guidelines are posing the most significant challenge.