<abstract xmlns="http://www.w3.org/1999/xhtml">

<p>Although kidney transplantation is the best treatment option for end stage kidney disease, it is still associated with long-term graft failure. One of the greater challenges for transplant professionals is the ability to identify grafts with a high risk of failure before initial decline of eGFR with irreversible graft changes. Transplantation medicine is facing an emerging need for novel disease end point-specific biomarkers, with practical application in preventive screening, early diagnostic, and improved prognostic and therapeutic utility. The aim of our review was to evaluate the clinical application of urinary proteomics in kidney transplant recipients at risk for any type of future graft failure.</p>
</abstract>

Although kidney transplantation is the best treatment option for end stage kidney disease, it is still associated with long-term graft failure. One of the greater challenges for transplant professionals is the ability to identify grafts with a high risk of failure before initial decline of eGFR with irreversible graft changes. Transplantation medicine is facing an emerging need for novel disease end point-specific biomarkers, with practical application in preventive screening, early diagnostic, and improved prognostic and therapeutic utility. The aim of our review was to evaluate the clinical application of urinary proteomics in kidney transplant recipients at risk for any type of future graft failure.

Urinary Proteomics in Kidney Transplantation

Department of Nephrology, Medical Faculty

PRILOZI

This work is licensed under the Creative Commons Attribution-NonCommercial-NoDerivatives 4.0 International License.

{"article-title":"Urinary Proteomics in Kidney Transplantation"}

Although kidney transplantation is the best treatment option for end stage kidney disease, it is still associated with long-term graft failure. One of the...

Urinary Proteomics in Kidney Transplantation

Pubblicato online: 30 dic 2021

Pagine: 7 - 16

DOI: https://doi.org/10.2478/prilozi-2021-0030

Parole chiave
kidney transplantation, proteomics, chronic allograft nephropathy

© 2021 Ioannis Chrysikos, published by Sciendo

This work is licensed under the Creative Commons Attribution-NonCommercial-NoDerivatives 4.0 International License.

Urinary Proteomics in Kidney Transplantation

Pubblicato online: 30 dic 2021

Pagine: 7 - 16

DOI: https://doi.org/10.2478/prilozi-2021-0030

Parole chiavekidney transplantation, proteomics, chronic allograft nephropathy

© 2021 Ioannis Chrysikos, published by Sciendo

This work is licensed under the Creative Commons Attribution-NonCommercial-NoDerivatives 4.0 International License.

Parole chiave
kidney transplantation, proteomics, chronic allograft nephropathy