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Borie R, Danel C, Debray M-P, Taille C, Dombret M-C, Aubier M, et al. Pulmonary alveolar proteinosis. The European Respiratory Review. 2011;20(120): 98–107.BorieRDanelCDebrayM-PTailleCDombretM-CAubierMPulmonary alveolar proteinosis2011201209810710.1007/978-1-4471-2401-6_18Search in Google Scholar
Rosen SH, Castleman B, Liebow AA. Pulmonary alveolar proteinosis. The New England Journal of Medicine. 1958:258(23): 1123–1142.RosenSHCastlemanBLiebowAAPulmonary alveolar proteinosis1958258231123114210.1056/NEJM195806052582301Search in Google Scholar
Inoue Y, Trapnell BC, Tazawa R, Arai T, Takada T, Hizawa N, et al. Characteristics of a large cohort of patients with autoimmune pulmonary alveolar proteinosis in Japan. American Journal of Respiratory and Critical Care Medicine. 2008;177: 752–762.InoueYTrapnellBCTazawaRAraiTTakadaTHizawaNCharacteristics of a large cohort of patients with autoimmune pulmonary alveolar proteinosis in Japan200817775276210.1164/rccm.200708-1271OCSearch in Google Scholar
Bonella F, Bauer PC, Griese M, Ohshimo S, Guzman J, Costabel U. Pulmonary alveolar proteinosis: new insights from a single-center cohort of 70 patients. Respiratory Medicine. 2011:105(12): 1908–1916.BonellaFBauerPCGrieseMOhshimoSGuzmanJCostabelUPulmonary alveolar proteinosis: new insights from a single-center cohort of 70 patients2011105121908191610.1016/j.rmed.2011.08.018Search in Google Scholar
Whitsett JA, Wert SE, Weaver TE. Alveolar surfactant homeostasis and the pathogenesis of pulmonary disease. Annual Review of Medicine. 2010;61: 105–119.WhitsettJAWertSEWeaverTEAlveolar surfactant homeostasis and the pathogenesis of pulmonary disease20106110511910.1146/annurev.med.60.041807.123500Search in Google Scholar
Shibata Y, Berclaz PY, Chroneos ZC, Yoshida M, Whitsett JA, Trapnell BC. GM-CSF regulates alveolar macrophage differentiation and innate immunity in the lung through PU.1. Immunity. 2001;15: 557–567.ShibataYBerclazPYChroneosZCYoshidaMWhitsettJATrapnellBCGM-CSF regulates alveolar macrophage differentiation and innate immunity in the lung through PU.120011555756710.1016/S1074-7613(01)00218-7Search in Google Scholar
Kitamura T, Tanaka N, Watanabe J, Uchida, Kanegasaki S, Yamada Y, et al. Idiopathic pulmonary alveolar proteinosis as an autoimmune disease with neutralizing antibody against granulocyte/macrophage colony-stimulating factor. The Journal of Experimental Medicine. 1999;190: 875–880.KitamuraTTanakaNWatanabeJUchidaKanegasakiSYamadaYIdiopathic pulmonary alveolar proteinosis as an autoimmune disease with neutralizing antibody against granulocyte/macrophage colony-stimulating factor199919087588010.1084/jem.190.6.875219562710499925Search in Google Scholar
Kitamura T, Uchida K, Tanaka N, Tsuchiya T, Watanabe J, Yamada Y, et al. Serological diagnosis of idiopathic pulmonary alveolar proteinosis. American Journal of Respiratory and Critical Care Medicine. 2000;162:658–662.KitamuraTUchidaKTanakaNTsuchiyaTWatanabeJYamadaYSerological diagnosis of idiopathic pulmonary alveolar proteinosis200016265866210.1164/ajrccm.162.2.991003210934102Search in Google Scholar
Costabel U, Guzman J. Pulmonary alveolar proteinosis: a new autoimmune disease. Sarcoidosis Vasculitis and Diffuse Lung Disease. 2005;22(Suppl 1): 67S–73S.CostabelUGuzmanJPulmonary alveolar proteinosis: a new autoimmune disease200522Suppl 167S73SSearch in Google Scholar
Dirksen U, Hattenhorst U, Schneider P, Schroten H, Göbel U, Böcking A, et al. Defective expression of granulocyte-macrophage colony-stimulating factor/interleukin-3/interleukin-5 receptor common beta chain in children with acute myeloid leukemia associated with respiratory failure. Blood. 1998;92: 1097–1103.DirksenUHattenhorstUSchneiderPSchrotenHGöbelUBöckingADefective expression of granulocyte-macrophage colony-stimulating factor/interleukin-3/interleukin-5 receptor common beta chain in children with acute myeloid leukemia associated with respiratory failure19989210971103Search in Google Scholar
Ishii H, Seymour JF, Tazawa R, Inoue Y, Uchida N, Nishida A, et al. Secondary pulmonary alveolar proteinosis complicating myelodysplastic syndrome results in worsening of prognosis: a retrospective cohort study in Japan. BMC Pulmonary Medicine. 2014;14: 37.IshiiHSeymourJFTazawaRInoueYUchidaNNishidaASecondary pulmonary alveolar proteinosis complicating myelodysplastic syndrome results in worsening of prognosis: a retrospective cohort study in Japan2014143710.1186/1471-2466-14-37394619024597668Search in Google Scholar
Ishii H, Tazawa R, Kaneko C, Saraya T, Inoue Y, Hamano E, et al. Clinical features of secondary pulmonary alveolar proteinosis: pre-mortem cases in Japan. European Respiratory Journal. 2011;37(2): 465–468.IshiiHTazawaRKanekoCSarayaTInoueYHamanoEClinical features of secondary pulmonary alveolar proteinosis: pre-mortem cases in Japan201137246546810.1183/09031936.0009291021282812Search in Google Scholar
Heppleston AG, Wright NA, Stewart JA. Experimental alveolar lipo-proteinosis following the inhalation of silica. The Journal of Pathology. 1970;101(4): 293–307.HepplestonAGWrightNAStewartJAExperimental alveolar lipo-proteinosis following the inhalation of silica1970101429330710.1002/path.17110104024323445Search in Google Scholar
Cummings KJ, Donat WE, Ettensohn DB, Roggli VL, Ingram P, Kreiss K. Pulmonary alveolar proteinosis in workers at an indium processing facility. American Journal of Respiratory and Critical Care Medicine. 2010;181(5): 458–464.CummingsKJDonatWEEttensohnDBRoggliVLIngramPKreissKPulmonary alveolar proteinosis in workers at an indium processing facility2010181545846410.1164/rccm.200907-1022CR315908620019344Search in Google Scholar
Suzuki T, Sakagami T, Young LR, Carey BC, Wood RE, Luisetti M, et al. Hereditary pulmonary alveolar proteinosis: pathogenesis, presentation, diagnosis, and therapy. American Journal of Respiratory and Critical Care Medicine. 2010;182: 1292–1304.SuzukiTSakagamiTYoungLRCareyBCWoodRELuisettiMHereditary pulmonary alveolar proteinosis: pathogenesis, presentation, diagnosis, and therapy20101821292130410.1164/rccm.201002-0271OC300126620622029Search in Google Scholar
Suzuki T, Sakagami T, Rubin BK, Nogee LM, Wood RE, Zimmerman SL, et al. Familial pulmonary alveolar proteinosis caused by mutations in CSF2RA. The Journal of Experimental Medicine. 2008;205(12): 2703–2710.SuzukiTSakagamiTRubinBKNogeeLMWoodREZimmermanSLFamilial pulmonary alveolar proteinosis caused by mutations in CSF2RA2008205122703271010.1084/jem.20080990258584518955570Search in Google Scholar
Tredano M, Griese M, Brasch F, Schumacher S, de Blic J, Marque S, et al. Mutation of SFTPC in infantile pulmonary alveolar proteinosis with or without fibrosing lung disease. American Journal of Medical Genetics Part A. 2004;126(1): 18–26.TredanoMGrieseMBraschFSchumacherSde BlicJMarqueSMutation of SFTPC in infantile pulmonary alveolar proteinosis with or without fibrosing lung disease20041261182610.1002/ajmg.a.2067015039969Search in Google Scholar
Shah PL, Hansell D, Lawson PR, Reid KB, Morgan C. Pulmonary alveolar proteinosis: clinical aspects and current concepts on pathogenesis. Thorax. 2000;55(1): 67–77.ShahPLHansellDLawsonPRReidKBMorganCPulmonary alveolar proteinosis: clinical aspects and current concepts on pathogenesis2000551677710.1136/thorax.55.1.67174559510607805Search in Google Scholar
Goldstein LS, Kavuru MS, Curtis-McCarthy P, Christie HA, Farver C, Stoller JK. Pulmonary alveolar proteinosis: clinical features and outcomes. Chest. 1998;114(5): 1357–1362.GoldsteinLSKavuruMSCurtis-McCarthyPChristieHAFarverCStollerJKPulmonary alveolar proteinosis: clinical features and outcomes199811451357136210.1378/chest.114.5.13579824014Search in Google Scholar
Lee KN, Levin DL, Webb WR, Chen D, Storto ML, Golden JA. Pulmonary alveolar proteinosis: high-resolution CT, chest radiographic, and functional correlations. Chest. 1997;111(4): 989–995.LeeKNLevinDLWebbWRChenDStortoMLGoldenJAPulmonary alveolar proteinosis: high-resolution CT, chest radiographic, and functional correlations1997111498999510.1378/chest.111.4.9899106579Search in Google Scholar
Holbert JM, Costello P, Li W, Hoffman RM, Rogers RM. CT features of pulmonary alveolar proteinosis. American Journal of Roentgenology. 2001;176: 1287–1294.HolbertJMCostelloPLiWHoffmanRMRogersRMCT features of pulmonary alveolar proteinosis20011761287129410.2214/ajr.176.5.176128711312196Search in Google Scholar
Johkoh T, Itoh H, Muller NL, Ichikado K, Nakamura H, Ikezoe J, et al. Crazy-paving appearance at thin-section CT: spectrum of disease and pathologic findings. Radiology. 1999;211: 155–160.JohkohTItohHMullerNLIchikadoKNakamuraHIkezoeJCrazy-paving appearance at thin-section CT: spectrum of disease and pathologic findings199921115516010.1148/radiology.211.1.r99ap1015510189465Search in Google Scholar
Ishii H, Trapnell BC, Tazawa R, Inoue Y, Akira M, Kogure Y, et al. Comparative study of high-resolution CT findings between auto-immune and secondary pulmonary alveolar proteinosis. Chest. 2009;136(5): 1348–1355.IshiiHTrapnellBCTazawaRInoueYAkiraMKogureYComparative study of high-resolution CT findings between auto-immune and secondary pulmonary alveolar proteinosis200913651348135510.1378/chest.09-0097Search in Google Scholar
Rossi SE, Erasmus JJ, Volpacchio M, Franquet T, Castiglioni T, McAdams HP. “Crazy-paving” pattern at thin-section CT of the lungs: radiologic-pathologic overview. Radiographics. 2003;23(6): 1509–1519.RossiSEErasmusJJVolpacchioMFranquetTCastiglioniTMcAdamsHP“Crazy-paving” pattern at thin-section CT of the lungs: radiologic-pathologic overview20032361509151910.1148/rg.236035101Search in Google Scholar
Costabel U, Guzman J, Bonella F, Oshimo S. Bronchoalveolar lavage in other interstitial lung diseases. Seminars in Respiratory and Critical Care Medicine. 2007;28(5): 514–524.CostabelUGuzmanJBonellaFOshimoSBronchoalveolar lavage in other interstitial lung diseases200728551452410.1055/s-2007-991525Search in Google Scholar
Milleron BJ, Costabel U, Teschler H, Ziesche R, Cadranel JL, Matthys H, et al. Bronchoalveolar lavage cell data in alveolar proteinosis. American Review of Respiratory Disease. 1991;144: 1330–1332.MilleronBJCostabelUTeschlerHZiescheRCadranelJLMatthysHBronchoalveolar lavage cell data in alveolar proteinosis19911441330133210.1164/ajrccm/144.6.1330Search in Google Scholar
Delaval P, Brinchault G, Corre R, Jouneau S, Meunier C, Briens E. Lipoproteinose alveolaire pulmonaire [Pulmonary alveolar phospholipoproteinosis]. Revue de Pneumologie Clinique. 2005;61: 186–192.DelavalPBrinchaultGCorreRJouneauSMeunierCBriensELipoproteinose alveolaire pulmonaire [Pulmonary alveolar phospholipoproteinosis]20056118619210.1016/S0761-8417(05)84811-4Search in Google Scholar
Bonfield TL, Russell D, Burgess S, Malur A, Kavuru MS, Thomassen MJ. Autoantibodies against granulocyte macrophage colony-stimulating factor are diagnostic for pulmonary alveolar proteinosis. American Journal of Respiratory Cell and Molecular Biology. 2002;27(4): 481–486.BonfieldTLRussellDBurgessSMalurAKavuruMSThomassenMJAutoantibodies against granulocyte macrophage colony-stimulating factor are diagnostic for pulmonary alveolar proteinosis200227448148610.1165/rcmb.2002-0023OC12356582Search in Google Scholar
Uchida K, Nakata K, Trapnell BC, Terakawa T, Hamano E, Mikami A, et al. High-affinity autoantibodies specifically eliminate granulocyte-macrophage colony-stimulating factor activity in the lungs of patients with idiopathic pulmonary alveolar proteinosis. Blood. 2004;103(3):1089–1098.UchidaKNakataKTrapnellBCTerakawaTHamanoEMikamiAHigh-affinity autoantibodies specifically eliminate granulocyte-macrophage colony-stimulating factor activity in the lungs of patients with idiopathic pulmonary alveolar proteinosis200410331089109810.1182/blood-2003-05-156514512323Search in Google Scholar
Uchida K, Nakata K, Suzuki T, Luisetti M, Watanabe M, Koch DE, et al. Granulocyte/macrophage colony-stimulating factor autoantibodies and myeloid cell immune functions in healthy individuals. Blood. 2009;113: 2547–2556.UchidaKNakataKSuzukiTLuisettiMWatanabeMKochDEGranulocyte/macrophage colony-stimulating factor autoantibodies and myeloid cell immune functions in healthy individuals20091132547255610.1182/blood-2008-05-155689Search in Google Scholar
Sergeeva A, Ono Y, Rios R, Molldrem JJ. High titer auto-antibodies to GM-CSF in patients with AML, CML and MDS are associated with active disease. Leukemia. 2008:22(4): 783–790.SergeevaAOnoYRiosRMolldremJJHigh titer auto-antibodies to GM-CSF in patients with AML, CML and MDS are associated with active disease200822478379010.1038/sj.leu.2405104340338118216869Search in Google Scholar
Ishikawa N, Hattori N, Yokoyama A, Kohno N. Utility of KL-6/MUC1 in the clinical management of interstitial lung diseases. Respiratory Investigation. 2012;50(1): 3–13.IshikawaNHattoriNYokoyamaAKohnoNUtility of KL-6/MUC1 in the clinical management of interstitial lung diseases201250131310.1016/j.resinv.2012.02.00122554854Search in Google Scholar
Bonella F, Campo I. Pulmonary alveolar proteinosis. Pneumologia. 2014;144: 147–155.BonellaFCampoIPulmonary alveolar proteinosis2014144147155Search in Google Scholar
Leth S, Bendstrup E, Vestergaard H, Hilberg O. Autoimmune pulmonary alveolar proteinosis: treatment options in year 2013. Respirology 2013;18(1): 82–91.LethSBendstrupEVestergaardHHilbergOAutoimmune pulmonary alveolar proteinosis: treatment options in year 20132013181829110.1111/j.1440-1843.2012.02274.x23036113Search in Google Scholar
Luisetti M. Call for an international survey on therapeutic lavage for pulmonary alveolar proteinosis. European Respiratory Journal. 2012;39(4): 1049.LuisettiMCall for an international survey on therapeutic lavage for pulmonary alveolar proteinosis2012394104910.1183/09031936.0022631122467731Search in Google Scholar
Ramirez J, Schultz RB, Dutton RE. Pulmonary alveolar proteinosis: a new technique and rationale for treatment. Archives of Internal Medicine. 1963;112: 419–431.RamirezJSchultzRBDuttonREPulmonary alveolar proteinosis: a new technique and rationale for treatment196311241943110.1001/archinte.1963.0386003017302114045290Search in Google Scholar
Seymour JF, Presneill JJ, Schoch OD, Downie GH, Moore PE, Doyle IR, et al. Therapeutic efficacy of granulocyte-macrophage colony-stimulating factor in patients with idiopathic acquired alveolar proteinosis. American Journal of Respiratory and Critical Care Medicine. 2001;163(2): 524–531.SeymourJFPresneillJJSchochODDownieGHMoorePEDoyleIRTherapeutic efficacy of granulocyte-macrophage colony-stimulating factor in patients with idiopathic acquired alveolar proteinosis2001163252453110.1164/ajrccm.163.2.200314611179134Search in Google Scholar
Venkateshiah SB, Yan TD, Bonfield TL, Thomassen MJ, Meziane M, Czich C, et al. An open-label trial of granulocyte macrophage colony stimulating factor therapy for moderate symptomatic pulmonary alveolar proteinosis. Chest. 2006;130(1): 227–223.VenkateshiahSBYanTDBonfieldTLThomassenMJMezianeMCzichCAn open-label trial of granulocyte macrophage colony stimulating factor therapy for moderate symptomatic pulmonary alveolar proteinosis2006130122722310.1378/chest.130.1.22716840407Search in Google Scholar
Wylam ME, Ten R, Prakash UB, Nadrous HF, Clawson ML, Anderson PM. Aerosol granulocyte-macrophage colony-stimulating factor for pulmonary alveolar proteinosis. European Respiratory Journal. 2006;27(3): 585–593.WylamMETenRPrakashUBNadrousHFClawsonMLAndersonPMAerosol granulocyte-macrophage colony-stimulating factor for pulmonary alveolar proteinosis200627358559310.1183/09031936.06.0005830516507860Search in Google Scholar
Tazawa R, Trapnell BC, Inoue Y, Arai T, Takada T, Nasuhara Y, et al. Inhaled granulocyte/macrophage-colony stimulating factor as therapy for pulmonary alveolar proteinosis. American Journal of Respiratory and Critical Care Medicine. 2010;181(12): 1345–1354.TazawaRTrapnellBCInoueYAraiTTakadaTNasuharaYInhaled granulocyte/macrophage-colony stimulating factor as therapy for pulmonary alveolar proteinosis2010181121345135410.1164/rccm.200906-0978OC289441020167854Search in Google Scholar
Tanner LM, Kurko J, Tringham M, Aho H, Mykkänen J, Näntö-Salonen K, et al. Inhaled sargramostim induces resolution of pulmonary alveolar proteinosis in lysinuric protein intolerance. JIMD Reports. 2017;34: 97–104.TannerLMKurkoJTringhamMAhoHMykkänenJNäntö-SalonenKInhaled sargramostim induces resolution of pulmonary alveolar proteinosis in lysinuric protein intolerance2017349710410.1007/8904_2016_15550954127783330Search in Google Scholar
Onkouchi S, Akasara K, Ichiwata T, Hisata S, Iijima H, Takada T, et al. Sequential granulocyte-macrophage-colony-stimulating factor after whole lung lavage for pulmonary alveolar proteinosis for pulmonary alveolar proteinosis. A report of five intractable cases. Annals of the American Thoracic Society. 2017;14: 1298.OnkouchiSAkasaraKIchiwataTHisataSIijimaHTakadaTSequential granulocyte-macrophage-colony-stimulating factor after whole lung lavage for pulmonary alveolar proteinosis for pulmonary alveolar proteinosis. A report of five intractable cases201714129810.1513/AnnalsATS.201611-892BC28421817Search in Google Scholar
Tazawa R, Ueda T, Abe M, Tatsumi K, Eda R, Kondoh S, et al. Inhaled GM-CSF for Pulmonary Alveolar Proteinosis. The New England Jorunal of Medicine. 2019;381(10): 923–932.TazawaRUedaTAbeMTatsumiKEdaRKondohSInhaled GM-CSF for Pulmonary Alveolar Proteinosis20193811092393210.1056/NEJMoa181621631483963Search in Google Scholar
Kavuru MS, Bonfield TL, Thomassen MJ. Plasmapheresis, GM-CSF, and alveolar proteinosis. American Journal of Respiratory and Critical Care Medicine. 2003;167(7): 1036–1037.KavuruMSBonfieldTLThomassenMJPlasmapheresis, GM-CSF, and alveolar proteinosis200316771036103710.1164/ajrccm.167.7.95012663343Search in Google Scholar
Luisetti M, Rodi G, Perotti C, Campo I, Mariani F, Pozzi E, et al. Plasmapheresis for treatment of pulmonary alveolar proteinosis. European Respiratory Journal. 2009;33(5): 1220–1222.LuisettiMRodiGPerottiCCampoIMarianiFPozziEPlasmapheresis for treatment of pulmonary alveolar proteinosis20093351220122210.1183/09031936.0009750819407056Search in Google Scholar
Kavuru MS, Malur A, Marshall I, Barna BP, Meziane M, Huizar I, et al. An open-label trial of rituximab therapy in pulmonary alveolar proteinosis. European Respiratory Journal. 2011;38(6): 1361–1367.KavuruMSMalurAMarshallIBarnaBPMezianeMHuizarIAn open-label trial of rituximab therapy in pulmonary alveolar proteinosis20113861361136710.1183/09031936.00197710387472521478218Search in Google Scholar
Sovez B, Borie R, Menard C, Cadranel J, Chavez L, Cottin V, et al. Rituximab for auto-immune alveolar proteinosis, a real life cohort. Respiratory Research. 2018;19: 74.SovezBBorieRMenardCCadranelJChavezLCottinVRituximab for auto-immune alveolar proteinosis, a real life cohort2018197410.1186/s12931-018-0780-5591890129695229Search in Google Scholar
Stoica R, Macri A, Cordos I, Bolca C. Whole lung lavage for pulmonary alveolar proteinosis after surgery for spontaneous pneumothorax. Journal of Medicine and Life. 2012;5(3): 311–315.StoicaRMacriACordosIBolcaCWhole lung lavage for pulmonary alveolar proteinosis after surgery for spontaneous pneumothorax201253311315Search in Google Scholar