Synthesis, spectroscopic and thermogravimetric interpretations of UO₂(II), ZrO(II), Zr(IV), VO(II) and V(V) ciprofloxacin antibiotic drug complexes

New five ciprofloxacin (CIP) complexes of dioxouranium(II), oxozirconium(II), zirconium(IV), oxovanadium(II) and vanadium(IV) in the proportion 1:2 have been prepared using CIP as a drug chelate with UO₂(NO₃)₂. 6H₂O, ZrOCl₂. _8H2O, ZrCl₄, VOSO₄. xH₂O and V₂O₅ respectively. The CIP complexes have been characterized based on the elemental analysis, molar conductance, magnetic, (FTIR & ¹HNMR) spectral and thermal studies. The molar conductance studies of the synthesized complexes in DMSO solvent with concentration of 10^–3 M indicate their non-electrolytic properties. At room temperature, the magnetic moment measurements revealed a diamagnetic behavior for all CIP prepared complexes. The different formulas of the new complexes can be represented as [UO₂(CIP)₂(NO₃)₂] (I), [VO(CIP)₂(SO₄)(H₂O)] (II), [V₂(O)(O₂)₂(CIP)₂] (III), [Zr(O)(CIP)₂(Cl)₂] (IV), and [Zr(CIP)₂(Cl)₄] (V). The thermal analysis data of the complexes indicates the absence of coordinated water molecules except for vanadyl(II) complex (II). The CIP chelate is a uni-dentate ligand coordinated to the mentioned metal ion through terminal piperazinyl nitrogen. The transmission electron microscopy (TEM) investigation confirms the nano-structured form of the complexes.