Antimicrobial materials properties based on ion-exchange 4A zeolite derivatives

Zeolites are nanoporous alumina silicates in a framework with cations, exhibiting ion-exchange properties with metal ions making them possible antimicrobial materials. The aim of this study was to evaluate the antimicrobial activity of ion-exchanged zeolites and the toxic potential of these materials. Zeolite-Co²⁺ and Li⁺ exhibited the most effective inhibition on Staphylococcus aureus growth than in other microorganisms (Escherichia coli and Pseudomonas aeroginosa) in low concentrations. Zeolite-Cu²⁺ presented higher zone of inhibition when tested against Candida albicans, while Zeolite-Zn²⁺ showed similar effectiveness among all the microorganisms. When ion-exchanged zeolites were used in effective concentrations to achieve antimicrobial activity, no alterations against bioindicators organisms as Artemia sp. and L. sativa were found and, in addition, they have non-significant result in terms of DNA cleavage activity. Zeolites have advantage of releasing slowly the metals loaded and this characteristic can to be considered promising as potential antimicrobial materials in concentrations safe for use.