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Nukleonika
Volume 66 (2021): Numero 4 (December 2021)
Accesso libero
Sub-cellular elemental imaging of human muscle tissues affected by neuromuscular diseases
Patrycja Śliż-Szpytma
Patrycja Śliż-Szpytma
,
Marek Lankosz
Marek Lankosz
,
Joanna Dudała
Joanna Dudała
,
Dariusz Adamek
Dariusz Adamek
,
Edyta Radwanska
Edyta Radwanska
,
Borys Kwinta
Borys Kwinta
,
Milko Jakšić
Milko Jakšić
,
Iva Božičević Mihalić
Iva Božičević Mihalić
e
Georgios Provatas
Georgios Provatas
| 25 nov 2021
Nukleonika
Volume 66 (2021): Numero 4 (December 2021)
INFORMAZIONI SU QUESTO ARTICOLO
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CONDIVIDI
Article Category:
Original Paper
Pubblicato online:
25 nov 2021
Pagine:
159 - 164
Ricevuto:
29 dic 2020
Accettato:
12 mar 2021
DOI:
https://doi.org/10.2478/nuka-2021-0024
Parole chiave
Dystrophy
,
Elemental analysis
,
Myopathy
,
Neurodegenerative diseases
,
PIXE
© 2021 Patrycja Śliż-Szpytma et al., published by Sciendo
This work is licensed under the Creative Commons Attribution-NonCommercial-NoDerivatives 4.0 International License.
Fig. 1
View of the measuring chamber.
Fig. 2
Optical microscope photo with superimposed STIM image. The red rectangles on the image represent the scan areas of point measurements for control sample.
Fig. 3
Element distribution maps of control sample made with the PIXE method.
Fig. 4
Maps of the elemental distribution of point no. 1 located on control sample.
Fig. 5
Optical microscope photo with superimposed STIM image. The red rectangles on the image represent the scan areas of point measurements for dystrophy sample.
Fig. 6
Element distribution maps of dystrophy sample made with the PIXE method.
Fig. 7
Selected maps of the elemental distribution for point no. 3 – dystrophy sample.
Fig. 8
Box-and-whisker plots for the Kruskal–Wallis test for individual elements with mean values (inner box), means ± standard error (outer box), and means ± standard deviation (whiskers).
Fig. 9
A graph of the configuration of points representing three types of muscle tissue samples in a layout determined by discriminant variables (axes).
Partial Wilks’ lambda values
Partial Wilks’ lambda
K
S
Na
Cl
P
Mg
Zn
Fe
Br
0.24
0.70
0.95
0.59
0.65
0.93
0.99
0.99
0.99