<abstract xmlns="http://www.w3.org/1999/xhtml">

<sec id="j_jvetres-2020-0023_s_005">
<h3>Introduction</h3>
<p>The therapeutic effect of subcutaneous embedding and revascularisation on the repair of canine bone defects caused by open fracture was examined.</p>
</sec>
<sec id="j_jvetres-2020-0023_s_006">
<h3>Material and Methods</h3>
<p>A total of 12 adult beagle dogs were randomly split into a control group (group C) and a test group (group T). A section of the radius was removed from each dog under general anaesthesia and the deficit supported by an orthopaedic implant. Group T had the section surgically implanted next to the blood vessel–rich saphenous vein and Group C had it cryopreserved at −80°C. After eight weeks, the bone was surgically implanted back into the matching radial deficit. Bone healing was evaluated by gross morphological and X-ray examinations, post-mortem histology, and successive blood measurements of key bone biochemical markers.</p>
</sec>
<sec id="j_jvetres-2020-0023_s_007">
<h3>Results</h3>
<p>At 12 weeks, the bone healing boundary was disappearing more quickly in group T dogs than in their group C counterparts. X-ray and histological examinations showed that the cortical repair of group T subjects was complete and the bony plate arrangement was more regular than that in group C. The levels of bone biochemical markers also proved that the healing state of group T was better.</p>
</sec>
<sec id="j_jvetres-2020-0023_s_008">
<h3>Conclusion</h3>
<p>The results showed that the degree of healing, osteoclast activity, and bone formation status of group T were better than those of group C, proving that the vascularised bone graft had a significantly shorter healing time than the cryopreserved bone graft.</p>
</sec>
</abstract>

Introduction
The therapeutic effect of subcutaneous embedding and revascularisation on the repair of canine bone defects caused by open fracture was examined.


Material and Methods
A total of 12 adult beagle dogs were randomly split into a control group (group C) and a test group (group T). A section of the radius was removed from each dog under general anaesthesia and the deficit supported by an orthopaedic implant. Group T had the section surgically implanted next to the blood vessel–rich saphenous vein and Group C had it cryopreserved at −80°C. After eight weeks, the bone was surgically implanted back into the matching radial deficit. Bone healing was evaluated by gross morphological and X-ray examinations, post-mortem histology, and successive blood measurements of key bone biochemical markers.


Results
At 12 weeks, the bone healing boundary was disappearing more quickly in group T dogs than in their group C counterparts. X-ray and histological examinations showed that the cortical repair of group T subjects was complete and the bony plate arrangement was more regular than that in group C. The levels of bone biochemical markers also proved that the healing state of group T was better.


Conclusion
The results showed that the degree of healing, osteoclast activity, and bone formation status of group T were better than those of group C, proving that the vascularised bone graft had a significantly shorter healing time than the cryopreserved bone graft.

Therapeutic effects of revascularisation on the healing of free bone grafts in dogs

Journal of Veterinary Research

This work is licensed under the Creative Commons Attribution-NonCommercial-NoDerivatives 3.0 License.

Introduction
The therapeutic effect of subcutaneous embedding and revascularisation on the repair of canine bone defects caused by open fracture was...

Therapeutic effects of revascularisation on the healing of free bone grafts in dogs

Pubblicato online: 24 mar 2020

Pagine: 175 - 180

Ricevuto: 15 lug 2019

Accettato: 02 mar 2020

DOI: https://doi.org/10.2478/jvetres-2020-0023

Parole chiave
dog, vascularisation, bone defect, bone-callus, open fracture

© 2020 J.S. Zheng et al. published by Sciendo

This work is licensed under the Creative Commons Attribution-NonCommercial-NoDerivatives 3.0 License.

Therapeutic effects of revascularisation on the healing of free bone grafts in dogs

Pubblicato online: 24 mar 2020

Pagine: 175 - 180

Ricevuto: 15 lug 2019

Accettato: 02 mar 2020

DOI: https://doi.org/10.2478/jvetres-2020-0023

Parole chiavedog, vascularisation, bone defect, bone-callus, open fracture

© 2020 J.S. Zheng et al. published by Sciendo

This work is licensed under the Creative Commons Attribution-NonCommercial-NoDerivatives 3.0 License.

Parole chiave
dog, vascularisation, bone defect, bone-callus, open fracture