Diabetic Foot: Old Disease, New Challenges

Diabetes is a socially significant disease that brings a significant burden to healthcare systems worldwide. The vicious nature of the disease affects almost all of the systems and organs of the body. The foot is one of the most important and clinically significant areas where these complications are manifested. Diabetic foot gangrene is a leading cause of non-traumatic foot loss worldwide. Although the disease has been known for over a decade, understanding it has gone through highs and lows, leading to suboptimal results in many cases. In this review article, we focused on diabetic foot and the methods for evaluation and assessment of the condition to properly initiate adequate treatment.