<abstract xmlns="http://www.w3.org/1999/xhtml"><p> Beebread is processed pollen stored in the cells of the honeycomb, with the addition of various enzymes and honey, which undergoes lactic acid fermentation. Ethanolic extracts (EBBs) were obtained from three different samples of beebread from Poland. Assays were carried out for the determination of chemical composition (GC/MS), for the total phenolic content, and for the antioxidant and cytotoxic activities. The effects of beebread extracts (10, 20, 30, 50, 100 μg/mL) on the viability of the glioblastoma cell line (U87MG) were studied after 24 h, 48 h, and 72 h. Our results indicated a time-dependent inhibitory effect on the viability of U87MG cells treated EBB. The main inhibitory effect of EBB was observed after 72 h; EBB treatment decreased cell viability to 49 - 66%.</p></abstract>

Beebread is processed pollen stored in the cells of the honeycomb, with the addition of various enzymes and honey, which undergoes lactic acid fermentation. Ethanolic extracts (EBBs) were obtained from three different samples of beebread from Poland. Assays were carried out for the determination of chemical composition (GC/MS), for the total phenolic content, and for the antioxidant and cytotoxic activities. The effects of beebread extracts (10, 20, 30, 50, 100 μg/mL) on the viability of the glioblastoma cell line (U87MG) were studied after 24 h, 48 h, and 72 h. Our results indicated a time-dependent inhibitory effect on the viability of U87MG cells treated EBB. The main inhibitory effect of EBB was observed after 72 h; EBB treatment decreased cell viability to 49 - 66%.

Chemical composition and antioxidant activity of beebread, and its influence on the glioblastoma cell line (U87MG)

Department of Bromatology, Medical University of Białystok, Poland

Institute of Chemistry, University of Białystok, Poland

Journal of Apicultural Science

Beebread is processed pollen stored in the cells of the honeycomb, with the addition of various enzymes and honey, which undergoes lactic acid fermentation....

Chemical composition and antioxidant activity of beebread, and its influence on the glioblastoma cell line (U87MG)

Pubblicato online: 31 dic 2013

Pagine: 147 - 157

DOI: https://doi.org/10.2478/jas-2013-0025

Parole chiave
antioxidant activity, beebread, chemical composition, cytotoxicity, glioblastoma multiforme

This content is open access.

Chemical composition and antioxidant activity of beebread, and its influence on the glioblastoma cell line (U87MG)

Pubblicato online: 31 dic 2013

Pagine: 147 - 157

DOI: https://doi.org/10.2478/jas-2013-0025

Parole chiaveantioxidant activity, beebread, chemical composition, cytotoxicity, glioblastoma multiforme

This content is open access.

Parole chiave
antioxidant activity, beebread, chemical composition, cytotoxicity, glioblastoma multiforme