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Selenium - its role in physiology and endocrinology and as organoselenium compounds in oncology: A minireview

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21 nov 2024
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Ali W, Chen Y, Gandahi JA, Qazi IH, Sun J, Wang T, Liu Z, Zou H. Cross-talk between selenium nanoparticles and cancer treatment through autophagy. Biol Trace Elem Res 202, 2931–2940, 2024. Search in Google Scholar

Ansari JA, Malik JA, Ahmed S, Manzoor M, Ahemad N, Anwar S. Recent advances in the therapeutic applications of selenium nanoparticles. Mol Biol Rep 51, 688, 2024. Search in Google Scholar

Arsenyan P, Rubina K, Shestakova I, Domracheva I. 4-Methyl-1,2,3-selenadiazole-5-carboxylic acid amides: antitumor action and cytotoxic effect correlation. Eur J Med Chem 42, 635–640, 2007. Search in Google Scholar

Arthur JR, Morrice PC, Nicol F, Beddows SE, Boyd R, Hayes JD, Beckett GJ. The effects of selenium and copper deficiencies on glutathione S-transferase and glutathione peroxidase in rat liver. Biochem J 248, 539–544, 1987. Search in Google Scholar

Arthur JR, Nicol F, Beckett GJ. Hepatic iodothyronine 5’-deiodinase. The role of selenium. Biochem J 272, 537–540, 1990. Search in Google Scholar

Arthur JR, Beckett GJ. New metabolic roles for selenium. Proc Nutr Soc 53, 615–624, 1994. Search in Google Scholar

Bartalena L, Baldeschi L, Boboridis K, Eckstein A, Kahaly GJ, Marcocci C, Perros P, Salvi M, Wiersinga WM; European Group on Graves’ Orbitopathy (EUGOGO). The 2016 European Thyroid Association/European Group on Graves’ orbitopathy guidelines for the management of Graves’ orbitopathy. Eur Thyroid J 5, 9–26, 2016. Search in Google Scholar

Behne D, Kyriakopoulos A, Meinhold H, Kohrle J. Identification of type I iodothyronine 5’-deiodinase as a selenoenzyme. Biochem Biophys Res Commun 173, 1143–1149, 1990. Search in Google Scholar

Brtkova A, Brtko J. Selenium: metabolism and endocrines (minireview). Endocr Regul 30, 117–128, 1996. Search in Google Scholar

Bulow Pedersen I, Knudsen N, Carle A, Schomburg L, Kohrle J, Jorgensen T, Rasmussen LB, Ovesen L, Laurberg P. Serum selenium is low in newly diagnosed Graves’ disease: A population-based study. Clin Endocrinol (Oxf) 79, 584–590, 2013. Search in Google Scholar

Chen X, Yang G, Chen J, Chen X, Wen Z, Ge K. Studies on the relations of selenium and Keshan disease. Biol Trace Elem Res 2, 91–107, 1980. Search in Google Scholar

Chen Y, Wang K, Zhang D, Zhao Z, Huang J, Zhou L, Feng M, Shi J, Wei H, Li L, Wu Z, Zhang S. GPx6 is involved in the in vitro induced capacitation and acrosome reaction in porcine sperm. Theriogenology 156, 107–115, 2020. Search in Google Scholar

Chen W, Cheng H, Xia W. Progress in the surface functionalization of selenium nanoparticles and their potential application in cancer therapy. Antioxidants (Basel) 11, 1965, 2022. Search in Google Scholar

Chu FF, Doroshow JH, Esworthy RS. Expression, characterization, and tissue distribution of a new cellular seleniumdependent glutathione peroxidase, GSHPx-GI. J Biol Chem 268, 2571–2576, 1993. Search in Google Scholar

Dottore GR, Leo M, Casini G, Latrofa F, Cestari L, Sellari-Franceschini S, Nardi M, Vitti P, Marocci C, Marino M. Antioxidant actions of selenium in orbital fibroblasts: A basis for the effects of selenium in Graves´orbitopathy. Thyroid 2, 271–278, 2017. Search in Google Scholar

Duntas LH, Mantzou E, Koutras DA. Effects of asix month treatment with selenomethionine in patients with autoimmune thyroiditis. Eur J Endocrinol 148, 389–393, 2003. Search in Google Scholar

Duntas LH. The role of iodine and selenium in autoimmunethyroiditis. Horm Metab Res 47, 721–726, 2015. Search in Google Scholar

Duntas LH, Benvenga S. Selenium: An element for life. Endocrine 48, 756–775, 2015. Search in Google Scholar

Epp O, Ladenstein R, Wendel A. The refined structure of the selenoenzyme glutathione peroxidase at 0.2-nm resolution. Eur J Biochem 133, 51–69, 1983. Search in Google Scholar

Fernandes AP, Gandin V. Selenium compounds as therapeutic agents in cancer. Biochim Biophys Acta 1850, 1642–1660, 2015. Search in Google Scholar

Fickova M, Pravdova E, Rondhal L, Uher M, Brtko J. In vitro antiproliferative and cytotoxic activities of novel kojic acid derivatives: 5-benzyloxy-2-selenocyanatomethyl- and 5-methoxy-2-selenocyanatomethyl-4-pyranone. J Appl Toxicol 28, 554–559, 2008. Search in Google Scholar

Flohe L, Gunzler WA, Schock HH. Glutathione peroxidase: a selenoenzyme. FEBS Lett 32, 132–134, 1973. Search in Google Scholar

Flohe L, Toppo S, Orian L. The glutathione peroxidase family: Discoveries and mechanism. Free Radic Biol Med 187, 113–122. 2022. Search in Google Scholar

Foster LH, Sumar S. Selenium in health and disease: a review. Crit Rev Food Sci Nutr 37, 211–228, 1997. Search in Google Scholar

Frieben EE, Amin S, Sharma AK. Development of isoselenocyanate compounds’ syntheses and biological applications. J Med Chem 62, 5261–5275, 2019. Search in Google Scholar

Gandin V, Khalkar P, Braude J, Fernandes AP. Organic selenium compounds as potential chemotherapeutic agents for improved cancer treatment. Free Radic Biol Med 127, 80–97, 2018. Search in Google Scholar

Ganther HE. Selenium metabolism, selenoproteins and mechanisms of cancer prevention: complexities with thioredoxin reductase. Carcinogenesis 20, 1657–1666, 1999. Search in Google Scholar

Gartner R, Gasnier BC, Dietrich JW, Krebs B, Angstwurm MW. Selenium supplementation in patients with autoimmune thyroiditis decreases thyroid peroxidase antibodies concentrations. J Clin Endocrinol Metab 87, 1687–1691, 2002. Search in Google Scholar

Ghose A, Fleming J, El-Bayoumy K, Harrison PR. Enhanced sensitivity of human oral carcinomas to induction of apoptosis by selenium compounds: involvement of mitogen-activated protein kinase and Fas pathways. Cancer Res 61, 7479–7487, 2001. Search in Google Scholar

Giynas Ayhan M, Uguz F, Askin R, Gonen MS. The prevalence of depression and anxiety disorders in patients with euthyroid Hashimoto’s thyroiditis: a comparative study. Gen Hosp Psychiatry 36, 95–98, 2014. Search in Google Scholar

Guadano-Ferraz A, Obregon MJ, St Germain DL, Bernal J. The type 2 iodothyronine deiodinase is expressed primarily in glial cells in the neonatal rat brain. Proc Natl Acad Sci U S A 94, 10391–10396, 1997. Search in Google Scholar

Guo P, Wang Q, Liu J, Liu L, Zhao P, Cao Y, Liu Y, Qi C. Preparation of two organoselenium compounds and their induction of apoptosis to SMMC-7221 cells. Biol Trace Elem Res 154, 304–311, 2013. Search in Google Scholar

Hall L, Williams K, Perry AC, Frayne J, Jury JA. The majority of human glutathione peroxidase type 5 (GPX5) transcripts are incorrectly spliced: implications for the role of GPX5 in the male reproductive tract. Biochem J 333, 5–9, 1998. Search in Google Scholar

Holben DH, Smith AM. The diverse role of selenium within selenoproteins: a review. J Am Diet Assoc 99, 836–843, 1999. Search in Google Scholar

Hunakova L, Horvathova E, Matuskova M, Bobal P, Otevrel J, Brtko J. In vitro antiproliferative and cytotoxic activities of novel triphenyltin isoselenocyanate in human breast carcinoma cell lines MCF 7 and MDA-MB-231. Med Oncol 39, 99, 2022. Search in Google Scholar

Jolly J, Mohd Ahmar R, Zeeshan A. Selenium nanoparticles: Small is the new big: Mini review. Open J Chem 6, 13–16, 2020. Search in Google Scholar

Khong JJ, Goldsteins RF, Sanders KM, Schneider K, Pope J, Burdon KP, Craig JE, Ebeling PR. Serum selenium status in Graves’ disease with and without orbitopathy: A case control study. Clin Endocrinol (Oxf) 80, 905–910, 2014. Search in Google Scholar

Kohrl J, Brigelius-Flohe R, Bock A, Gartner R, Meyer O, Flohe L. Selenium in biology: facts and medical perspectives. Biol Chem 381, 849–864, 2000. Search in Google Scholar

Kohrle J. Iodothyronine deiodinases. Methods Enzymol 347, 125–167, 2002. Search in Google Scholar

Kohrle J. Selenium and the control of thyroid hormone metabolism. Thyroid 15, 841‒853, 2005. Search in Google Scholar

Kohrle J, Jakob F, Contempre B, Dumont JE. Selenium, the thyroid, and the endocrine system. Endocr Rev 26, 944–984, 2005. Search in Google Scholar

Kohrle J, Fradrich C. Deiodinases control local cellular and systemic thyroid hormone availability. Free Radic Biol Med 193, 59–79, 2022. Search in Google Scholar

Kohrle J. Selenium, iodine and iron-essential trace elements for thyroid hormone synthesis and metabolism. Int J Mol Sci 24, 3393, 2023. Search in Google Scholar

Kostic M, Marjanovic J, Divac V. Organoselenium transition metal complexes as promising candidates in medicine area. J Biol Inorg Chem 29, 555–571, 2024. Search in Google Scholar

Liu J, Duan Y, Fu J, Wang G. Association between thyroid hormones, thyroid antibodies, and cardiometabolic factors in non-obese individuals with normal thyroid function. Front Endocrinol 9, 130, 2018. Search in Google Scholar

Macejova D, Kollar J, Bobal P, Otevrel J, Schuster D, Brtko J. Triphenyltin isoselenocyanate: A novel nuclear retinoid X receptor ligand with antiproliferative and cytotoxic properties in cell lines derived from human breast cancer. Mol Cell Biochem 479, 3091–3106, 2024. Search in Google Scholar

Maddipati KR, Marnett LJ. Characterization of the major hydroperoxide-reducing activity of human plasma. Purification and properties of a selenium-dependent glutathione peroxidase. J Biol Chem 262, 17398–17403, 1987. Search in Google Scholar

Mantovani G, Isidori AM, Moretti C, Di Dato C, Greco E, Ciolli P, Bonomi M, Petrone L, Fumarola A, Campagna G, Vannucchi G, Di Sante S, Pozza C, Faggiano A, Lenzi A, Giannetta E. Selenium supplementation in the management of thyroid autoimmunity during pregnancy: Results of the “SERENA study”, a randomized, double-blind, placebo-controlled trial. Endocrine 66, 542–550, 2019. Search in Google Scholar

Marcocci C, Kahaly GJ, Krassas GE, Bartalena L, Prummel M, Stahl M, Altea MA, Nardi M, Pitz S, Boboridis K, Sivelli P, von Arx G, Mourits MP, Baldeschi L, Bencivelli W, Wiersinga W; European Group on Graves’ Orbitopathy. Selenium and the course of mild Graves’ orbitopathy. N Engl J Med 364, 1920–1931, 2011. Search in Google Scholar

Milner JA, Hsu CY. Inhibitory effects of selenium on the growth of L1210 leukemic cells. Cancer Res 41, 1652–1656, 1981. Search in Google Scholar

Moreno-Reyes R, Suetens C, Mathieu F, Begaux F, Zhu D, Rivera MT, Boelaert M, Neve J, Perlmutter N, Vanderpas J. Kashin-Beck osteoarthropathy in rural Tibet in relation to selenium and iodine status. N Engl J Med 339, 1112–1120, 1998. Search in Google Scholar

Moreno-Reyes R, Mathieu F, Boelaert M, Begaux F, Suetens C, Rivera MT, Neve J, Perlmutter N, Vanderpas J. Selenium and iodine supplementation of rural Tibetan children affected by Kashin-Beck osteoarthropathy. Am J Clin Nutr 78, 137–144, 2003. Search in Google Scholar

Nam SY, Maeda S, Fujisawa M, Kurohmaru M, Hayashi Y. Expression pattern of mitochondrial capsule selenoprotein mRNA in the hamster testis. J Vet Med Sci 60, 1175–1179, 1998. Search in Google Scholar

Negro R, Greco G, Mangieri T, Pezzarossa A, Dazzi D, Hassan H. The influence of selenium supplementation on postpartum thyroid status in pregnant women with thyroid peroxidase autoantibodies. J Clin Endocrinol Metab 92, 1263–1268, 2007. Search in Google Scholar

Nettore IC. Selenium supplementation modulates apoptotic processes in thyroid follicular cells. Biofactors 43, 415–423, 2017. Search in Google Scholar

Oldfield JE. The two faces of selenium. J Nutr 117, 2002–2008, 1987. Search in Google Scholar

Pinto JT, Sinha R, Papp K, Facompre ND, Desai D, El-Bayoumy K. Differential effects of naturally occurring and synthetic organoselenium compounds on biomarkers in androgen responsive and androgen independent human prostate carcinoma cells. Int J Cancer 120, 1410–1417, 2007. Search in Google Scholar

Podoba J, Hnilica P, Srbecky M, Bednar J. Thyroid volume, goitre and diffuse lymphoid thyroiditis in adolescents after long-term iodine prophylaxis in Slovakia. J Endocr Invest 15, Suppl 5, 14, 1992. Search in Google Scholar

Qiu C, Zhang T, Zhu X, Qiu J, Jiang K, Zhao G, Wu H, Deng G. Methylseleninic acid suppresses breast cancer growth via the JAK2/STAT3 pathway. Reprod Sci 26, 829–838, 2019. Search in Google Scholar

Read R, Bellew T, Yang JG, Hill KE, Palmer IS, Burk RF. Selenium and amino acid composition of selenoprotein P, the major selenoprotein in rat serum. J Biol Chem 265, 17899–17905, 1990. Search in Google Scholar

Rondahl L, Uher M, Brtko J. Syntheses and structure determinations of some selenocyanato- and thiocyanatokojic acid derivatives. Heterocycl Commun 9, 257–258, 2003. Search in Google Scholar

Rotruck JT, Pope AL, Ganther HE, Swanson AB, Hafeman DG, Hoekstra WG. Selenium: biochemical role as a component of glutathione peroxidase. Science 179, 588–590, 1973. Search in Google Scholar

Sampath S, Sunderam V, Manjusha M, Dlamini Z, Lawrance AV. Selenium nanoparticles: A comprehensive examination of synthesis techniques and their diverse applications in medical research and toxicology studies. Molecules 29, 801, 2024. Search in Google Scholar

Shin SH, Yoon MJ, Kim M, Kim JI, Lee SJ, Lee YS, Bae S. Enhanced lung cancer cell killing by the combination of selenium and ionizing radiation. Oncol Rep 17, 209–216, 2007. Search in Google Scholar

Schwarz K, Foltz CM. Selenium as an integral part of factor 3 against dietary necrotic liver degeneration. 1951. Nutrition 15, 255, 1999. Search in Google Scholar

Tamer C, Mert M, Tamer I, Mesci B, Kilic D, Arik S. Effects of thyroid autoimmunity on abdominal obesity and hyperlipidaemia. Endokrynol Pol 62, 421–428, 2011. Search in Google Scholar

Toulis KA, Anastasilakis AD, Tzellos DG, Goulis DG, Kouvelas D. Selenium supplementation in the treatment of Hashimoto’s thyroiditis: A systematic review and meta-analysis. Thyroid 20, 1163–1173, 2010. Search in Google Scholar

Ullah A, Mu J, Wang F, Chan MWH, Yin X, Liao Y, Mirani ZA, Sebt-E-Hassan S, Aslam S, Naveed M, Khan MN, Khatoon Z, Kazmi MR. Biogenic selenium nanoparticles and their anticancer effects pertaining to probiotic bacteria - A review. Antioxidants (Basel) 11, 1916, 2022. Search in Google Scholar

Varlamova EG. Molecular mechanisms of the therapeutic effect of selenium nanoparticles in hepatocellular carcinoma. Cells 13, 1102, 2024. Search in Google Scholar

Ventura M, Melo M, Carrilho F. Selenium and thyroid disease: From pathophysiology to treatment. Int J Endocrinol 2017, 1297658, 2017. Search in Google Scholar

Wang L, Hu H, Wang Z, Xiong H, Cheng Y, Liao JD, Deng Y, Lu J. Methylseleninic acid suppresses pancreatic cancer growth involving multiple pathways. Nutr Cancer 66, 295–307, 2014. Search in Google Scholar

Wertenbruch T, Willenberg HS, Sagert C, Nguyen TB, Bahlo M, Feldkamp J, Groeger C, Hermsen D, Scherbaum WA, Schott M. Serum selenium levels in patients with remission and relapse of Graves´disease. Med Chem 3, 281–284. 2007. Search in Google Scholar

Whanger PD. Selenoprotein expression and function-selenoprotein W. Biochim Biophys Acta 1790, 1448–145, 2009. Search in Google Scholar

White PJ. Selenium accumulation by plants. Ann Bot 117, 217–235, 2016. Search in Google Scholar

Wichman J, Winther KH, Bonnema SJ, Hegedus L. Selenium supplementation significantly reduces thyroid autoantibody levels in patients with chronic autoimmune thyroiditis: A systematic review and metaanalysis. Thyroid 26, 1681–1692, 2016. Search in Google Scholar

Wimmer I, Hartmann T, Brustbauer R, Minear G, Dam K. Selenium levels in patients with autoimmune thyroiditis and controls in lower Austria. Horm Metab Res, 46, 707–709, 2014. Search in Google Scholar

Wu Y, Shi X, Tang X, Li Y, Tong N, Wang G, Zhang JA, Wang Y, Ba J, Chen B, Du J, He L, Lai X, Li Y, Chi H, Liao E, Liu C, Liu L, Qin G, Qin Y, Quan H, Shi B, Sun H, Xue Y, Yan L, Yang J, Yang L, Yao Y, Ye Z, Zhang Q, Zhang L, Zhu J, Zhu M, Teng W, Shan Z. The correlation between metabolic disorders and Tpoab/Tgab: A cross-sectional population-based study. Endocr Pract 26, 869–882, 2020. Search in Google Scholar

Yalcin MM, Altinova AE, Cavnar B, Bolayir B, Akturk M, Arslan E, Ozkan C, Cakir N, Balos Toruner F. Is thyroid autoimmunity itself associated with psychological well-being in euthyroid Hashimoto‘s thyroiditis? Endocr J 64, 425–429, 2017. Search in Google Scholar

Zachara BA. Mammalian selenoproteins. J Trace Elem Electrolytes Health Dis 6, 137–151, 1992. Search in Google Scholar