[
Alam F, Syed H, Amjad S, Baig M, Khan TA, Rehman R. Interplay between oxidative stress, SIRT1, reproductive and metabolic functions. Curr Res Physiol 4, 119–124, 2021.
]Search in Google Scholar
[
Ali FF, Mokhemer SA, Ali DME. Administration of hemin ameliorates ovarian ischemia reperfusion injury via modulation of heme oxygenase-1 and p-JNK/p-NF-κBp65/iNOS signaling pathway. Life Sci 296, 120431, 2021.
]Search in Google Scholar
[
Ali FF, Mohammed HH, Ali, DME. Protective effect of hydrogen sulfide against stress-induced lung injury: involvement of Nrf2, NFκB/iNOS, and HIF-1α signaling pathways. Cell Stress Chaperones 27, 55–70, 2022.
]Search in Google Scholar
[
Alshaheen TA, Awaad MH, Mehaisen GM. Leptin improves the in vitro development of preimplantation rabbit embryos under oxidative stress of cryopreservation. PLoS One 16, e0246307, 2021.
]Search in Google Scholar
[
Becerril S, Rodriguez A, Catalan V, Ramirez B, Unamuno X, Portincasa P, Gomez-Ambrosi J, Fruhbeck G. Functional relationship between leptin and nitric oxide in metabolism. Nutrients 11, 2129, 2019.
]Search in Google Scholar
[
Bilbao MG, Di Yorio MP, Galarza RA, Varone CL, Faletti AG. Regulation of the ovarian oxidative status by leptin during the ovulatory process in rats. Reproduction 149, 357–366, 2015.
]Search in Google Scholar
[
Buldak RJ, Pilc-Gumuła K, Buldak L, Witkowska D, Kukla M, Polaniak R, Zwirska-Korczala K. Effects of ghrelin, leptin and melatonin on the levels of reactive oxygen species, antioxidant enzyme activity and viability of the HCT 116 human colorectal carcinoma cell line. Mol Med Rep 12, 2275–2282, 2015.
]Search in Google Scholar
[
Caprio M, Fabbrini E, Isidori AM, Aversa A, Fabbri A. Leptin in reproduction. Trends Endocrinol Metabol 12, 65–72, 2001.
]Search in Google Scholar
[
Catteau A, Caillon H, Barriere P, Denis M, Masson D, Freour, T. Leptin and its potential interest in assisted reproduction cycles. Hum Reprod Update 22, 320–341, 2016.
]Search in Google Scholar
[
Cavalcante FS, Aiceles V, da Fonte Ramos C. Leptin regulates gonadotropins and steroid receptors in the rats ovary. Nutr Hosp 28, 164–168, 2013.
]Search in Google Scholar
[
Colak S, Gurlek B, Topcu A, Tumkaya L, Mercantepe T, Yilmaz A. Protective effects of nebivolol on ovarian ischemia–reperfusion injury in rat. J Obstet Gynaecol Res 46, 2407–2416, 2020.
]Search in Google Scholar
[
Council NR. Guide for the Care and use of Laboratory Animals, 8th edition. Washington (DC): National Academies Press (US), 2011.
]Search in Google Scholar
[
Demir M, Yilmaz B, Kalyoncu S, Tuncer M, Bozdag Z, Ince O, Bozdayi MA, Ulusal H, Taysi S. Metformin reduces ovarian ischemia reperfusion injury in rats by improving oxidative/nitrosative stress. Taiwan J Obstet Gynecol 60, 45–50, 2021.
]Search in Google Scholar
[
Di Emidio G, Falone S, Vitti M, D’Alessandro AM, Vento M, Di Pietro C. SIRT1 signalling protects mouse oocytes against oxidative stress and is deregulated during aging. Hum Reprod 29, 2006–2017, 2014.
]Search in Google Scholar
[
Eken MK, Ersoy GS, Kaygusuz EI, Devranoglu B, Takır M, Cilingir OT, Cevik O. Etanercept protects ovarian reserve against ischemia/reperfusion injury in a rat model. Arch Med Sci 15, 1104–1112, 2019.
]Search in Google Scholar
[
Ekinci Akdemir FN, Tanyeli A, Guler MC, Eraslan E, Topdagi Yilmaz EP, Topdagi YE. Brusatol mitigates ovarian tissue oxidative injury induced by ovarian ischemia reperfusion. AKD Med J 7, 206–211, 2021.
]Search in Google Scholar
[
Erkasap S, Erkasap N, Koken T, Kahraman A, Uzuner K, Yazihan N, Ates E. Effect of leptin on renal ischemia-reper-fusion damage in rats. J Physiol Biochem 60, 79–84, 2004.
]Search in Google Scholar
[
Erkasap S, Erkasap N, Bradford B, Mamedova L, Uysal O, Ozkurt M. The effect of leptin and resveratrol on JAK/ STAT pathways and Sirt-1 gene expression in the renal tissue of ischemia/reperfusion induced rats. Bratisl Lek Listy, 118, 443–448, 2017.
]Search in Google Scholar
[
Faustmann G, Tiran B, Maimari T, Kieslinger P, Obermayer-Pietsch B, Gruber HJ, Roob JM, Winklhofer-Roob BM. Circulating leptin and NF-κB activation in peripheral blood mononuclear cells across the menstrual cycle. Biofactors 42, 376–387, 2016.
]Search in Google Scholar
[
Feng H, Zheng L, Feng Z, Zhao Y, Zhang N. The role of leptin in obesity and the potential for leptin replacement therapy. Endocrine 44, 33–39, 2013.
]Search in Google Scholar
[
Fernandez-Martos CM, Gonzalez P, Rodriguez FJ. Acute leptin treatment enhances functional recovery after spinal cord injury. PLoS One 7, e35594, 2012.
]Search in Google Scholar
[
Gipsyianti N, Aziz A, Hernowo BS, Usman HA. High Expression of COX-2 Associated with the Depth of Invasion on Acral Melanoma by Increasing TGF-β1. Clin Cosmet Investig Dermatol 14, 209, 2021.
]Search in Google Scholar
[
Hamm ML, Bhat GK, Thompson WE, Mann DR. Folliculogenesis is impaired and granulosa cell apoptosis is increased in leptin-deficient mice. Biol Reprod 71, 66–72, 2004.
]Search in Google Scholar
[
Hausman GJ, Barb CR, Lents CA. Leptin and reproductive function. Biochimie 94, 2075–2081, 2012.
]Search in Google Scholar
[
Hepp M, Werion A, De Greef A, de Ville de Goyet C, de Bournonville M, Behets C, Lengele B, Daumerie C, Mourad M, Ludgate M, Many MC, Joris V, Craps J. Oxidative stress-induced sirtuin1 downregulation correlates to HIF-1α, GLUT-1, and VEGF-A upregulation in Th1 autoimmune Hashimoto’s thyroiditis. Int J Mol Sci 22, 3806, 2021.
]Search in Google Scholar
[
Iljas JD, Wei Z, Homer HA. Sirt1 sustains female fertility by slowing age-related decline in oocyte quality required for post-fertilization embryo development. Aging Cell 19, e13204, 2020.
]Search in Google Scholar
[
Iside C, Scafuro M, Nebbioso A, Altucci L. SIRT1 activation by natural phytochemicals: an overview. Front Pharmacol 1225, 2020.
]Search in Google Scholar
[
Joudah MS, Arif IS, Al-Sudani BT. Crosstalk between Sirt1 activators and Nf-Κb axis as a therapeutic target to reduce pancreatic cancer. Sys Rev Pharmacy 12, 207–212, 2021.
]Search in Google Scholar
[
Karimzadeh L, Nabiuni M, Kouchesfehani HM, Adham H, Bagheri A, Sheikholeslami A. Effect of bee venom on IL-6, COX-2 and VEGF levels in polycystic ovarian syndrome induced in Wistar rats by estradiol valerate. J Venom Anim Toxins Incl Trop Dis 19, 1–8, 2013.
]Search in Google Scholar
[
Kauppinen A, Suuronen T, Ojala J, Kaarniranta K, Salminen A. Antagonistic crosstalk between NF-κB and SIRT1 in the regulation of inflammation and metabolic disorders. Cell Signal 25, 1939–1948, 2013.
]Search in Google Scholar
[
Korinkova L, Holubova M, Neprasova B, Hruba L, Prazienkova V, Bencze M, Haluzik M, Kunes J, Maletinska L, Zelezna B. Synergistic effect of leptin and lipidized PrRP on metabolic pathways in ob/ob mice. J Mol Endocrinol 64, 77–90, 2020.
]Search in Google Scholar
[
Kornowski R, Waldman M, Zemel R, Lev DL, Shainberg A, Miskin R, Hochhauser E. Leptin modulates gene expression in the heart, cardiomyocytes and the adipose tissue thus mitigating LPS-induced damage. Exp Cell Res 404, 112647, 2021.
]Search in Google Scholar
[
Kumar PA, Sivakumar A, Pathipati D, Chakravarthi VP, Brahmaiah K, Rao V. Leptin induced in vitro development of ovarian follicles in sheep is related to the expression of P450 aromatase and steroidogenesis. Theriogenology 136, 1–6, 2019.
]Search in Google Scholar
[
Malik IA, Durairajanayagam D, Singh HJ. Leptin and its actions on reproduction in males. Asian J Androl 21, 296, 2019.
]Search in Google Scholar
[
Marwarha G, Raza S, Meiers C, Ghribi O. Leptin attenuates BACE1 expression and amyloid-β genesis via the activation of SIRT1 signaling pathway. Biochim Biophys Acta 1842, 1587–1595, 2014.
]Search in Google Scholar
[
Melekoglu R, Ciftci O, Eraslan S, Alan S, Basak N. The protective effects of glycyrrhetinic acid and chrysin against ischemia-reperfusion injury in rat ovaries. Biomed Res Int 2018, 5421308, 2018.
]Search in Google Scholar
[
Menezes V, Monte A, Gouveia B, Lins T, Donfack N, Macedo T, Barberino RS, Santos JM, Matos MHT, Batista AM, Wischral A. Effects of leptin on the follicular development and mitochondrial activity of ovine isolated early antral follicles cultured in vitro. Theriogenology 138, 77–83, 2019.
]Search in Google Scholar
[
Naseri R, Barzingarosi E, Sohrabi M, Alimoradi Y, Fard MC, Jalili C. The effect of leptin receptor gene polymorphisms (R223Q and P1019P) in susceptibility to polycystic ovarian syndrome in Kurdish women. Int J Fertil Steril 15, 123, 2021.
]Search in Google Scholar
[
Nishigaki A, Tsubokura H, Tsuzuki-Nakao T, Okada H. Hypoxia: Role of SIRT1 and the protective effect of resveratrol in ovarian function. Reprod Med Biol 21, e12428, 2022.
]Search in Google Scholar
[
Perez-Perez A, Sanchez-Jimenez F, Maymo J, Duenas JL, Varone C, Sanchez-Margalet V. Role of leptin in female reproducion. Clin Chem Lab Med, 53, 15–28, 2015.
]Search in Google Scholar
[
Pico C, Palou M, Pomar CA, Rodriguez AM, Palou A. Leptin as a key regulator of the adipose organ. Rev Endocr Metab Disord 1–18, 2021.
]Search in Google Scholar
[
Ragy M, RaMzy M. Leptin and curcumin affect renal ischemia-reperfusion injury via modulation of P65 and Bax genes expression. Ukr Biochem J 93, 51–58, 2021.
]Search in Google Scholar
[
Refaie MM, El-Hussieny M. Protective effect of pioglitazone on ovarian ischemia reperfusion injury of female rats via modulation of peroxisome proliferator activated receptor gamma and heme-oxygenase 1. Int Immunopharmacol 62, 7–14, 2018.
]Search in Google Scholar
[
Refaie MM, El-Hussieny M Shehata S. TLR4/NF-κB/TNFα and cAMP/SIRT1 signaling cascade involved in mediating the dose-dependent effect of cilostazol in ovarian ischemia reperfusion-induced injury. Immunopharmacol Immunotoxicol 1–9, 2022.
]Search in Google Scholar
[
Ren J, Fan C, Chen N, Huang J, Yang Q. Resveratrol pretreatment attenuates cerebral ischemic injury by upregulating expression of transcription factor Nrf2 and HO-1 in rats. Neurochem Res 36, 2352–2362, 2011.
]Search in Google Scholar
[
Salem AM. Variation of leptin during Menstrual cycle and its relation to the hypothalamic–pituitary–gonadal (HPG) axis: A systematic review. Int J Women’s Health, 13, 445, 2021.
]Search in Google Scholar
[
Sarsu SB, Ozokutan BH, Tarakcioglu M, Sari, I, Bagci, C. Effects of leptin on intestinal ischemia–reperfusion injury. Indian J Surg 77, 351–355, 2015.
]Search in Google Scholar
[
Shaikat AH, Ochiai M, Sasaki A, Takeda M, Arima A, Ohkubo T. Leptin modulates early follicle development in chicks at age-dependent manner. Front Physiol 12, 1015, 2021.
]Search in Google Scholar
[
Song NY, Lee YH, Na HK, Baek JH, Surh J. Leptin induces SIRT1 expression through activation of NF-E2-related factor 2: Implications for obesity-associated colon carcinogenesis. Biochem Pharmacol 153, 282–291, 2018.
]Search in Google Scholar
[
Sun H, Zhou Z, Xuan H, Yan Z. Anti-inflammatory and protective effects of combined treatment with sitagliptin and melatonin in cardiac ischemia reperfusion injury in obese rats: Involvement of TLR-4/NF-κB pathway. Eur J Inflammation 19, 2021.
]Search in Google Scholar
[
VanGuilder HD, Vrana KE, Freeman WM. Twenty-five years of quantitative PCR for gene expression analysis. Bio-techniques 44, 619–626, 2008.
]Search in Google Scholar
[
Yildirim N, Yigitturk G, Sahingoz Yildirim AG, Akdemir A, Ilgen O, Yeniel O, Ergenoglu M, Erbas O. Octreotide protects ovary against ischemia–reperfusion injury in rats: Evaluation of histological and biochemical parameters. J Obstet Gynaecol Res 41, 1591–1597, 2015.
]Search in Google Scholar
[
Yilmaz E, Gul M, Melekoglu R, Koleli I. Immunhistochemical analysis of nuclear factor kappa Beta expression in etiopathogenesis of ovarian tumors. Acta Cir Bras 33, 641–650, 2018.
]Search in Google Scholar
[
Yilmaz EPT, Un H, Gundogdu B, Polat E, Askin S, Topdagi YE, Halici Z. Protective effect of lycopene against reper-fusion injury in rats with ovarian torsion: a biochemical and histopathological evaluation. J Lab Physicians 12, 32–37, 2020.
]Search in Google Scholar
[
Zachow RJ, Weitsman SR, Magoffin DA. Leptin impairs the synergistic stimulation by transforming growth factor-β of follicle-stimulating hormone-dependent aromatase activity and messenger ribonucleic acid expression in rat ovarian granulosa cells. Biol Reprod 61, 1104–1109, 1999.
]Search in Google Scholar
[
Zhang B, Zhai M, Li B, LiuZ., Li K, Jiang L, Zhang M, Yi W, Yang J, Yi D, Liang H, Jin Z, Duan W, Yu S. Honokiol ameliorates myocardial ischemia/reperfusion injury in type 1 diabetic rats by reducing oxidative stress and apoptosis through activating the SIRT1-Nrf2 signaling pathway. Oxid Med Cell Longev 2018, 3159801, 2018.
]Search in Google Scholar
[
Zhang WF, Jin YC, Li XM, YangZ, Wang D, Cui JJ. Protective effects of leptin against cerebral ischemia/reperfusion injury. Exp Therap Med 17, 3282–3290, 2019.
]Search in Google Scholar
[
Zhu H, Lin Y, Liu Y. miR-34a increases inflammation and oxidative stress levels in patients with necrotizing enterocolitis by downregulating SIRT1 expression. Mol Med Rep 24, 1–9, 2021.
]Search in Google Scholar