This work is licensed under the Creative Commons Attribution-NonCommercial-NoDerivatives 4.0 License.
American Cancer Society, Global Cancer Facts & Figures 3rd Edition. 2015, American Cancer Society: Atlanta.2015American Cancer SocietyAtlantaSearch in Google Scholar
National Cancer Institute. Probability of Developing or Dying of Cancer. 2015 [cited 2016] ; Available from: srab.cancer.gov/devcan2015[cited 2016] ; Available fromsrab.cancer.gov/devcanSearch in Google Scholar
Bray F, Jemal A, Grey N, Ferlay J, Forman D. Global cancer transitions according to the Human Development Index (2008-2030): a population-based study. Lancet Oncology. 2012. 13: 790-801.10.1016/S1470-2045(12)70211-5BrayFJemalAGreyNFerlayJFormanDGlobal cancer transitions according to the Human Development Index (2008-2030): a population-based study201213790801Open DOISearch in Google Scholar
Vollmers HP, Brandlein S. Natural antibodies and cancer. Journal of Autoimmunity. 2007. 29(4): 295-302.10.1016/j.jaut.2007.07.01317826951VollmersHPBrandleinSNatural antibodies and cancer200729429530217826951Open DOISearch in Google Scholar
Beneduce L, Prayer-Galletti T, Marcello Grimani Giustinian A, Gallotta A, Betto G, Pagano F, Fassina G. Detection of prostate specific antigen coupled to immunoglobulin M In prostate cancer patients. Cancer Detection and Prevention. 2007. 31: 402-407.1803550310.1016/j.cdp.2007.10.005BeneduceLPrayer-GallettiTMarcello Grimani GiustinianAGallottaABettoGPaganoFFassinaGDetection of prostate specific antigen coupled to immunoglobulin M In prostate cancer patients20073140240718035503Search in Google Scholar
Castaldi F, Marino M, Beneduce L, Belluco C, De Marchi F, Mammano E, Nitti D, Lise M, Fassina G. Detection of circulating CEA-IgM complexes in early stage colorectal cancer. International Journal of Biological Markers. 2005. 20(4): 204-208.10.1177/172460080502000402CastaldiFMarinoMBeneduceLBellucoCDe MarchiFMammanoENittiDLiseMFassinaGDetection of circulating CEA-IgM complexes in early stage colorectal cancer200520420420816398401Open DOISearch in Google Scholar
Beneduce L, Castaldi F, Marino M, Quarta S, Ruvoletto M, Benvegnù L, Calabrese F, Gatta A, Pontisso P, Fassina G. Squamous cell carcinoma antigen-Immunoglobulin M complexes as novel biomarkers for hepatocellular carcinoma. Cancer. 2005. 103: 2558-2565.1588722210.1002/cncr.21106BeneduceLCastaldiFMarinoMQuartaSRuvolettoMBenvegnùLCalabreseFGattaAPontissoPFassinaGSquamous cell carcinoma antigen-Immunoglobulin M complexes as novel biomarkers for hepatocellular carcinoma20051032558256515887222Search in Google Scholar
Beneduce L, Castaldi F, Marino M, Tono N, Gatta A, Pontisso P, Fassina G. Improvement of liver cancer detection with simultaneous assessment of circulating levels of free alpha-fetoprotein (AFP) and AFP-IgM complexes. International Journal of Biological Markers. 2004. 19: 155-159.10.1177/172460080401900211BeneduceLCastaldiFMarinoMTonoNGattaAPontissoPFassinaGImprovement of liver cancer detection with simultaneous assessment of circulating levels of free alpha-fetoprotein (AFP) and AFP-IgM complexes20041915515915255549Open DOISearch in Google Scholar
Beneduce L, Pesce G, Gallotta A, Zampieri F, Biasiolo A, Tono N, Boscato N, Gatta A, Pontisso P, Fassina G. Tumour-specific induction of immune complexes: DCP-IgM in hepatocellular carcinoma. European Journal of Clinical Investigation. 2008. 38: 571-577.10.1111/j.1365-2362.2008.01985.x18625005BeneduceLPesceGGallottaAZampieriFBiasioloATonoNBoscatoNGattaAPontissoPFassinaGTumour-specific induction of immune complexes: DCP-IgM in hepatocellular carcinoma20083857157718625005Open DOISearch in Google Scholar
Martini A, Gallotta A, Pontisso P, Fassina G. Clinical applications of squamous cell carcinoma antigen_immunoglobulins M to monitor chronic hepatitis C. World Journal of Hepatology. 2015. 7(29): 2913-2919.10.4254/wjh.v7.i29.291326689503MartiniAGallottaAPontissoPFassinaGClinical applications of squamous cell carcinoma antigen_immunoglobulins M to monitor chronic hepatitis C201572929132919467837826689503Open DOISearch in Google Scholar
Biggins SW, Bambha KM, Terrault NA, Inadomi J, Shiboski S, Dodge JL, Gralla J, Rosen HR, Roberts JP. Projected future increase in aging hepatitis C virus-infected liver transplant candidates: a potential effect of hepatocellular carcinoma. Liver Transplantation. 2012. 18: 1471-1478.10.1002/lt.23551BigginsSWBambhaKMTerraultNAInadomiJShiboskiSDodgeJLGrallaJRosenHRRobertsJPProjected future increase in aging hepatitis C virus-infected liver transplant candidates: a potential effect of hepatocellular carcinoma20121814711478351867023008049Open DOISearch in Google Scholar
Davis GL, Alter MJ, El-Serag H, Poynard T, Jennings LW. Aging of hepatitis C virus (HCV)-infected persons in the United States: a multiple cohort model of HCV prevalence and disease progression. Gastroenterology. 2010. 138: 513-521.10.1053/j.gastro.2009.09.06719861128DavisGLAlterMJEl-SeragHPoynardTJenningsLWAging of hepatitis C virus (HCV)-infected persons in the United States: a multiple cohort model of HCV prevalence and disease progression201013851352119861128Open DOISearch in Google Scholar
EASL-EORTC. Clinical practice guidelines: management of hepatocellular carcinoma. Journal of Hepatology. 2012. 56: 908-943.22424438EASL-EORTCClinical practice guidelines: management of hepatocellular carcinoma20125690894310.1016/j.jhep.2011.12.001Search in Google Scholar
Bruix J,Sherman M. Management of hepatocellular carcinoma: an update.Hepatology. 2011. 53(3): 1020-1022.10.1002/hep.2419921374666BruixJShermanMManagement of hepatocellular carcinoma: an update201153310201022Open DOISearch in Google Scholar
Biasiolo A, Chemello L, Quarta S, Cavalletto L, Bortolotti F, Caberlotto C, Beneduce L, Bernardinello E, Tono N, Fassina G, Gatta A, Pontisso P. Monitoring SCCA-IgM complexes in serum predicts liver disease progression in patients with chronic hepatitis. Journal of Viral Hepatitis. 2008. 15: 246-249.10.1111/j.1365-2893.2007.00935.xBiasioloAChemelloLQuartaSCavallettoLBortolottiFCaberlottoCBeneduceLBernardinelloETonoNFassinaGGattaAPontissoPMonitoring SCCA-IgM complexes in serum predicts liver disease progression in patients with chronic hepatitis200815246249Open DOISearch in Google Scholar
Pontisso P,Quarta S, Caberlotto C, Beneduce L, Marino M, Bernardinello E, Tono N, Fassina G, Cavalletto L, Gatta A, Chemello L. Progressive increse of SCCA-IgM immune complexes in cirrhotic patients is associated with development of hepatocellular carcinoma. International Journal of Cancer. 2006. 119: 735-740.10.1002/ijc.21908PontissoPQuartaSCaberlottoCBeneduceLMarinoMBernardinelloETonoNFassinaGCavallettoLGattaAChemelloLProgressive increse of SCCA-IgM immune complexes in cirrhotic patients is associated with development of hepatocellular carcinoma2006119735740Open DOISearch in Google Scholar
Biasiolo A, Trotta E, Fasolato S, Ruvoletto M, Martini A, Gallotta A, Fassina G, Angeli P, Gatta A, Pontisso P. Squamous cell carcinoma antigen-IgM is associated with hepatocellular carcinoma in patients with cirrhosis: A prospective study.Digestive Liver Disease. 2016. 48(2): 197-202.10.1016/j.dld.2015.10.022BiasioloATrottaEFasolatoSRuvolettoMMartiniAGallottaAFassinaGAngeliPGattaAPontissoPSquamous cell carcinoma antigen-IgM is associated with hepatocellular carcinoma in patients with cirrhosis: A prospective study2016482197202Open DOISearch in Google Scholar
Buccione D, Fatti G, Gallotta A, Loggi E, Di Donato R, Testa L, Saitta C, Santi V, Di Micoli A, Erroi V, Frigerio M, Fazio V, Picciotto A, Biasiolo A, Degos F, Pontisso P, Raimondo G, Trevisani F. Serum SCCA-IgM as a predictor of hepatocellular carcinoma in patients with cirrhosis. Open Journal of Gastroenterology. 2012. 2: 56-61.10.4236/ojgas.2012.22012BuccioneDFattiGGallottaALoggiEDi DonatoRTestaLSaittaCSantiVDiMicoli AErroiVFrigerioMFazioVPicciottoABiasioloADegosFPontissoPRaimondoGTrevisaniFSerum SCCA-IgM as a predictor of hepatocellular carcinoma in patients with cirrhosis201225661Open DOISearch in Google Scholar
Morisco F,Guarino M, Di Costanzo GG, Gallotta A, Fassina G, Tortora R, Tuccillo C, Granata R, Loperto I, Auriemma F, Caporaso N. Circulating SCCA-IgM complex is a useful biomarker to predict the outcome of therapy in HCC patients. Journal of Hepatology. 2015. 62(S450).MoriscoFGuarinoMDi CostanzoGGGallottaAFassinaGTortoraRTuccilloCGranataRLopertoIAuriemmaFCaporasoNCirculating SCCA-IgM complex is a useful biomarker to predict the outcome of therapy in HCC patients201562S45010.1016/S0168-8278(15)30582-1Search in Google Scholar
Giannelli G, Fransvea E, Trerotoli P, Beaugrand M, Marinosci F, Lupo L, Nkontchou G, Dentico P, Antonaci S. Clinical validation of combined serological biomarkers for improved hepatocellular carcinoma diagnosis in 961 patients. Clinica Chimica Acta. 2007. 383: 147-152.10.1016/j.cca.2007.05.014GiannelliGFransveaETrerotoliPBeaugrandMMarinosciFLupoLNkontchouGDenticoPAntonaciSClinical validation of combined serological biomarkers for improved hepatocellular carcinoma diagnosis in 961 patients200738314715217582392Open DOISearch in Google Scholar
Crescenzi M, Tessari A, Biasiolo A, Padoan A, Gallotta A, Fassina G, Panciatichi C, Rossetto O, Pontisso P, Basso D, Plebani M. Analytical Validation of a biochip prototype for integrated analysis of AFPIgM and SCCA-IgM serum biomarkers in patients with liver cirrhosis and hepatocellular carcinoma.Analytical Methods. 2015(2): 626-637.CrescenziMTessariABiasioloAPadoanAGallottaAFassinaGPanciatichiCRossettoOPontissoPBassoDPlebaniMAnalytical Validation of a biochip prototype for integrated analysis of AFPIgM and SCCA-IgM serum biomarkers in patients with liver cirrhosis and hepatocellular carcinoma2015262663710.1039/C4AY02495HSearch in Google Scholar
Gil-Gómez A, Ampuero J, Gallego-Durán R, Fassina G, Pontisso P, Romero-Gomez M. SCCA-IgM helps to identify patients at risk of long-term hepatocellular carcinoma.Hepatology. 2016. 64(S1): 656A.Gil-GómezAAmpueroJGallego-DuránRFassinaGPontissoPRomero-GomezMSCCA-IgM helps to identify patients at risk of long-term hepatocellular carcinoma201664S1656ASearch in Google Scholar
Regione Veneto. Tariffario delle Prestazioni Specialistiche Ambulatoriali.Search in Google Scholar
Giannini EG,Cucchetti A, Erroi V, Garuti F, Odaldi F, Trevisani F. Surveillance for early diagnosis of hepatocellular carcinoma: how best to do it? World Journal of Gastroenterology. 2013. 19(47): 8808-8821.10.3748/wjg.v19.i47.8808GianniniEGCucchettiAErroiVGarutiFOdaldiFTrevisaniFSurveillance for early diagnosis of hepatocellular carcinoma: how best to do it?2013194788088821387053224379604Open DOISearch in Google Scholar
Thompson Coon J,Rogers G, Hewson P, Wright D, Anderson R, Jackson S, Ryder S, Cramp M, Stein K. Surveillance of cirrhosis for hepatocellular carcinoma: a cost-utility analysis. British Journal of Cancer. 2008. 98: 1166-1175.10.1038/sj.bjc.660430118382459Thompson CoonJRogersGHewsonPWrightDAndersonRJacksonSRyderSCrampMSteinKSurveillance of cirrhosis for hepatocellular carcinoma: a cost-utility analysis20089811661175235964118382459Open DOISearch in Google Scholar