<abstract xmlns="http://www.w3.org/1999/xhtml"><p>Metastatic tumours in the brain occur more frequently than primary neoplasms. Despite the generally dismal prognosis, neurosurgical resection is indicated in certain patients and can yield prolonged survival. Here we describe an 82-year-old male with a history of neurosurgical resection of a single brain metastasis 6 years ago. Tumour immunophenotype disclosed lung adenocarcinoma with low proliferation fraction. However, the primary tumour remained occult then. At present, 3 new brain metastases were identified by computed tomography. Repeated resection was performed in 2 stages, resulting in removal of 2 metastases. Lung mass was now evident as well. The final diagnosis was lung adenocarcinoma with metachronous brain metastases, stage IV. In conclusion, prolonged survival, in this case 6 years, can be reached even in patients with metastatic cancer by successful selective application of neurosurgical treatment. The biological properties of the tumour including low proliferation also contributed to longer survival and demonstrated surgery as a successful treatment option.</p></abstract>

Metastatic tumours in the brain occur more frequently than primary neoplasms. Despite the generally dismal prognosis, neurosurgical resection is indicated in certain patients and can yield prolonged survival. Here we describe an 82-year-old male with a history of neurosurgical resection of a single brain metastasis 6 years ago. Tumour immunophenotype disclosed lung adenocarcinoma with low proliferation fraction. However, the primary tumour remained occult then. At present, 3 new brain metastases were identified by computed tomography. Repeated resection was performed in 2 stages, resulting in removal of 2 metastases. Lung mass was now evident as well. The final diagnosis was lung adenocarcinoma with metachronous brain metastases, stage IV. In conclusion, prolonged survival, in this case 6 years, can be reached even in patients with metastatic cancer by successful selective application of neurosurgical treatment. The biological properties of the tumour including low proliferation also contributed to longer survival and demonstrated surgery as a successful treatment option.

Prolonged Survival After Neurosurgical Resection of Lung Cancer Metastasis

Pauls Stradins Clinical University Hospital, Latvia

Acta Chirurgica Latviensis

This work is licensed under the Creative Commons Attribution-NonCommercial-NoDerivatives 3.0 License.

{"article-title":"Prolonged Survival After Neurosurgical Resection of Lung Cancer Metastasis"}

Metastatic tumours in the brain occur more frequently than primary neoplasms. Despite the generally dismal prognosis, neurosurgical resection is indicated in...

Prolonged Survival After Neurosurgical Resection of Lung Cancer Metastasis

Article Category: Case Report

Pubblicato online: 24 nov 2014

Pagine: 32 - 34

DOI: https://doi.org/10.2478/chilat-2014-0106

Parole chiave
brain metastasis, neurosurgical resection, lung cancer, prolonged survival

© 2014 Gvido Janis Bergs et. al.

This work is licensed under the Creative Commons Attribution-NonCommercial-NoDerivatives 3.0 License.

Prolonged Survival After Neurosurgical Resection of Lung Cancer Metastasis

Article Category: Case Report

Pubblicato online: 24 nov 2014

Pagine: 32 - 34

DOI: https://doi.org/10.2478/chilat-2014-0106

Parole chiavebrain metastasis, neurosurgical resection, lung cancer, prolonged survival

© 2014 Gvido Janis Bergs et. al.

This work is licensed under the Creative Commons Attribution-NonCommercial-NoDerivatives 3.0 License.

Parole chiave
brain metastasis, neurosurgical resection, lung cancer, prolonged survival