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Kalman B, Toldy E. Genomic binding sites and biological effects of the vitamin D--VDR complex in multiple sclerosis. Neuromolecular Med. 2014; 16(2): 265-79.KalmanBToldyEGenomic binding sites and biological effects of the vitamin D--VDR complex in multiple sclerosis20141622657910.1007/s12017-014-8301-224711208Search in Google Scholar
Librau RS, Singer SM, McDevitt HO. Th1 and Th2 CD41 T cells in the pathogenesis of organ-specific autoimmune diseases. Immunol Today. 1995; 16: 34–48.LibrauRSSingerSMMcDevittHOTh1 and Th2 CD41 T cells in the pathogenesis of organ-specific autoimmune diseases199516344810.1016/0167-5699(95)80068-97880387Search in Google Scholar
Hasheminia SJ, Tolouei S, Zarkesh-Esfahani SH, Shaygannejad V, Shirzad HA, Torabi R, Hashem Zadeh Chaloshtory M. Cytokines gene expression in newly diagnosed multiple sclerosis patients. Iran J Allergy Asthma Immunol. 2015; 14(2): 208-16.HasheminiaSJToloueiSZarkesh-EsfahaniSHShaygannejadVShirzadHATorabiRHashem Zadeh Chaloshtory M. Cytokines gene expression in newly diagnosed multiple sclerosis patients201514220816Search in Google Scholar
Brück W. The pathology of multiple sclerosis is the result of focal inflammatory demyelination with axonal damage. J Neurol. 2005; 252(5):v3–9.BrückW.The pathology of multiple sclerosis is the result of focal inflammatory demyelination with axonal damage20052525v3910.1007/s00415-005-5002-716254699Search in Google Scholar
García-Martín E, Agúndez JA, Martínez C, Benito-León J, Millán-Pascual J, Calleja P, et al. Vitamin D3 receptor (VDR ) gene rs2228570 (Fok1) and rs731236 (Taq1) variants are not associated with the risk for multiple sclerosis: results of a new study and a meta-analysis. PLoS One. 2013; 8(6): e65487.García-MartínEAgúndezJAMartínezCBenito-LeónJMillán-PascualJCallejaPet alVitamin D3 receptor (VDR ) gene rs2228570 (Fok1) and rs731236 (Taq1) variants are not associated with the risk for multiple sclerosis: results of a new study and a meta-analysis201386e6548710.1371/journal.pone.0065487368872823840333Search in Google Scholar
Herrero-Herranz E, Pardo LA, Gold R, Linker RA. Pattern of axonal injury in murine myelin oligodendrocyte glycoprotein induced experimental autoimmune encephalomyelitis: implications for multiple sclerosis. Neurobiol Dis. 2008; 30: 162–73.Herrero-HerranzEPardoLAGoldRLinkerRAPattern of axonal injury in murine myelin oligodendrocyte glycoprotein induced experimental autoimmune encephalomyelitis: implications for multiple sclerosis2008301627310.1016/j.nbd.2008.01.00118342527Search in Google Scholar
Huang J, Xie Z. Polymorphisms in the vitamin D receptor gene and multiple sclerosis risk: A meta-analysis of case–control studies, Journal of the Neurological Sciences. 2012; 313: 79–85.HuangJXieZPolymorphisms in the vitamin D receptor gene and multiple sclerosis risk: A meta-analysis of case–control studies2012313798510.1016/j.jns.2011.09.02422029942Search in Google Scholar
Goldenberg MM. Multiple sclerosis review. P & T. 2012; 37(3): 175–84.GoldenbergMMMultiple sclerosis review201237317584Search in Google Scholar
Kurland LT. The frequency and geographic distribution of multiple sclerosis as indicated by mortality statistics and morbidity surveys in the United States and Canada. Amer. J. Hygiene. 1952; 55: 457–76.KurlandLTThe frequency and geographic distribution of multiple sclerosis as indicated by mortality statistics and morbidity surveys in the United States and Canada1952554577610.1093/oxfordjournals.aje.a11953514933384Search in Google Scholar
Pugliatti M, Harbo HF, Holmøy T, Kampman MT, Myhr KM, et al. Environmental risk factors in multiple sclerosis. Acta Neurol Scand Suppl. 2008; 188: 34–40.PugliattiMHarboHFHolmøyTKampmanMTMyhrKMet alEnvironmental risk factors in multiple sclerosis2008188344010.1111/j.1600-0404.2008.01029.x18439219Search in Google Scholar
Martina B. Sintzel . Mark Rametta . Anthony T. Reder. Vitamin D and Multiple Sclerosis: A Comprehensive Review. Neurol Ther. 2018; 7: 59–85.Martina B. Sintzel . Mark Rametta . Anthony T. RederVitamin D and Multiple Sclerosis: A Comprehensive Review20187598510.1007/s40120-017-0086-4599051229243029Search in Google Scholar
Ebers GC, Kukay K, Bulmann DE, et al. A full genome search in multiple sclerosis. Nat Genet. 1996; 13: 472–6.EbersGCKukayKBulmannDEet alA full genome search in multiple sclerosis199613472610.1038/ng0896-4728696345Search in Google Scholar
Sawcer S, Jones HB, Feakes R, et al. A genome screen in multiple sclerosis reveals susceptibility loci on chromosomes 6p21 and 17q22. Nat Genet. 1996; 13: 464–8.SawcerSJonesHBFeakesRet alA genome screen in multiple sclerosis reveals susceptibility loci on chromosomes 6p21 and 17q22199613464810.1038/ng0896-4648696343Search in Google Scholar
Fukazawaa T, Yabeb I, Kikuchib S, Sasakib H, Hamadaa T, Miyasaka K, et al. Association of vitamin D receptor gene polymorphism with multiple sclerosis in Japanese. Journal of the Neurological Sciences. 1999; 166: 47–52.FukazawaaTYabebIKikuchibSSasakibHHamadaaTMiyasakaKet alAssociation of vitamin D receptor gene polymorphism with multiple sclerosis in Japanese1999166475210.1016/S0022-510X(99)00112-4Search in Google Scholar
Ramagopalan SV, Maugeri NJ, Handunnetthi L, Lincoln MR, Orton SM, Dyment DA et al. Expression of the multiple sclerosis-associated MHC class II Allele HLA–DRB1*1501 is regulated by vitamin D. PloS Genet. 2009; 5: e1000369.RamagopalanSVMaugeriNJHandunnetthiLLincolnMROrtonSMDymentDAet alExpression of the multiple sclerosis-associated MHC class II Allele HLA–DRB1*1501 is regulated by vitamin D20095e100036910.1371/journal.pgen.1000369262789919197344Search in Google Scholar
Hewison M. Vitamin D and the immune system: new perspectives on an old theme. Rheumatic Disease Clinics of North America. 2012; 38(1): 125–39.HewisonMVitamin D and the immune system: new perspectives on an old theme20123811253910.1016/j.rdc.2012.03.01222525848Search in Google Scholar
Jurutka PW, Bartik L, Whitfield GK, et al. Vitamin D receptor: key roles in bone mineral pathophysiology, molecular mechanism of action, and novel nutritional ligands. Journal of Bone and Mineral Research. 2007; 22(2): v2-10.JurutkaPWBartikLWhitfieldGKet alVitamin D receptor: key roles in bone mineral pathophysiology, molecular mechanism of action, and novel nutritional ligands2007222v21010.1359/jbmr.07s21618290715Search in Google Scholar
Lemire JM, Archer DC. 1,25-dihydroxyvitamin D3 prevents the in vivo induction of murine experimental autoimmune encephalomyelitis. J Clin Invest. 1991; 87: 1103–7.LemireJMArcherDC1,25-dihydroxyvitamin D3 prevents the in vivo induction of murine experimental autoimmune encephalomyelitis1991871103710.1172/JCI1150723299071705564Search in Google Scholar
Cantorna MT, Hayes CE, DeLuca HF. 1,25-Dihydroxyvitamin D3 reversibly blocks the progression of relapsing encephalomyelitis, a model of multiple sclerosis. Proc Natl Acad Sci USA. 1996; 93: 7861–4.CantornaMTHayesCEDeLucaHF1,25-Dihydroxyvitamin D3 reversibly blocks the progression of relapsing encephalomyelitis, a model of multiple sclerosis1996937861410.1073/pnas.93.15.7861388398755567Search in Google Scholar
Meehan TF, DeLuca HF. The vitamin D receptor is necessary for 1α,25-dihydroxyvitamin D3 to suppress experimental autoimmune encephalomyelitis in mice. Archives of Biochemistry and Biophysics. 2002; 408(2): 200–4.MeehanTFDeLucaHFThe vitamin D receptor is necessary for 1α,25-dihydroxyvitamin D3 to suppress experimental autoimmune encephalomyelitis in mice20024082200410.1016/S0003-9861(02)00580-512464272Search in Google Scholar
Narooie-Nejad M, Moossavi M, Torkamanzehi A, Moghtaderi A. Positive Association of Vitamin D Receptor Gene Variations with Multiple Sclerosis in South East Iranian Population. Hindawi Publishing Corporation BioMed Research International. 2015; Article ID 427519: 1-4.Narooie-NejadMMoossaviMTorkamanzehiAMoghtaderiAPositive Association of Vitamin D Receptor Gene Variations with Multiple Sclerosis in South East Iranian Population2015Article ID4275191410.1155/2015/427519432088525685788Search in Google Scholar
Simon K, Munger K, Yang X, Ascherio A. Polymorphisms in vitamin D metabolism related genes and risk of multiple sclerosis. Multiple Sclerosis. 2010; 16(2): 133–8.SimonKMungerKYangXAscherioAPolymorphisms in vitamin D metabolism related genes and risk of multiple sclerosis2010162133810.1177/1352458509355069281963320007432Search in Google Scholar
Cox MB, Ban M, Bowden NA, Baker A, Scott RJ, Lechner-Scott J. Potential association of vitamin D receptor polymorphism Taq1 with multiple sclerosis. Mult Scler. 2012; 18(1): 16-22.CoxMBBanMBowdenNABakerAScottRJLechner-ScottJPotential association of vitamin D receptor polymorphism Taq1 with multiple sclerosis2012181162210.1177/135245851141556221816760Search in Google Scholar
Niino M, Fukazawa T, Yabe I, Kikuchi S, Sasaki H, Tashiro K. Vitamin D receptor gene polymorphism in multiple sclerosis and the association with HLA class II alleles. Journal of the Neurological Sciences. 2000; 177(1): 65–71.NiinoMFukazawaTYabeIKikuchiSSasakiHTashiroKVitamin D receptor gene polymorphism in multiple sclerosis and the association with HLA class II alleles20001771657110.1016/S0022-510X(00)00336-110967184Search in Google Scholar
Tajouri L, Ovcaric M, Curtain R, et al. Variation in the vitamin D receptor gene is associated with multiple sclerosis in an Australian population. J Neurogenet. 2005; 19(1): 25–38.TajouriLOvcaricMCurtainRet alVariation in the vitamin D receptor gene is associated with multiple sclerosis in an Australian population2005191253810.1080/0167706059094969216076630Search in Google Scholar
Uitterlinden AG, Fang Y, Van Meurs JB, Pols HA, Van Leeuwen JP. Genetics and biology of vitamin D receptor polymorphisms. Gene. 2004; 338: 143–56.UitterlindenAGFangYVan MeursJBPolsHAVan LeeuwenJPGenetics and biology of vitamin D receptor polymorphisms20043381435610.1016/j.gene.2004.05.01415315818Search in Google Scholar
McDonald WI, Compston A, Edan G, Goodkin D, Hartung HP, Lublin FD, McFarland HF, Paty DW, Polman CH, Reingold SC, Sandberg-Wollheim M, Sibley W, Thompson A, van den Noort S, Weinshenker BY, Wolinsky JS: Recommended diagnostic criteria for multiple sclerosis: guidelines from the International Panel on the diagnosis of multiple sclerosis. Ann Neurol. 2001, 50: 121-127.McDonaldWICompstonAEdanGGoodkinDHartungHPLublinFDMcFarlandHFPatyDWPolmanCHReingoldSCSandberg-WollheimMSibleyWThompsonAvan den NoortSWeinshenkerBYWolinskyJSRecommended diagnostic criteria for multiple sclerosis: guidelines from the International Panel on the diagnosis of multiple sclerosis20015012112710.1002/ana.103211456302Search in Google Scholar
Nasiri H, Forouzandeh M, Rasaee MJ and Rahbarizadeh F. Modified salting-out method: High-yield, high-quality genomic DNA extraction from whole blood using laundry detergent. J Clin Lab Anal. 2005; 19(6): 229-32.NasiriHForouzandehMRasaeeMJandRahbarizadehF.Modifiedsalting-out method: High-yield, high-quality genomic DNA extraction from whole blood using laundry detergent20051962293210.1002/jcla.20083680803016302208Search in Google Scholar
Smolders J, Peelen E, Thewissen M, Menheere P, Tervaert J, Hupperts R, Damoiseaux J. The relevance of vitamin D receptor gene polymorphisms for vitamin D research in multiple sclerosis. Autoimmunity Reviews. 2009; 8: 621–6.SmoldersJPeelenEThewissenMMenheerePTervaertJHuppertsRDamoiseauxJThe relevance of vitamin D receptor gene polymorphisms for vitamin D research in multiple sclerosis20098621610.1016/j.autrev.2009.02.00919393206Search in Google Scholar
Mamutse G, Woolmore J, Pye E, Partridge J, Boggild M, Young C, et al. Vitamin D receptor gene polymorphism is associated with reduced disability in multiple sclerosis. Mult Scler. 2008; 14: 1280–3.MamutseGWoolmoreJPyeEPartridgeJBoggildMYoungCet alVitamin D receptor gene polymorphism is associated with reduced disability in multiple sclerosis2008141280310.1177/135245850809464318653739Search in Google Scholar
Dickinson JL, Perera DI, van der Mei AF, Ponsonby AL, Polanowski AM, Thomson RJ, et al. Past environmental sun exposure and risk of multiple sclerosis: a role for the Cdx-2 Vitamin D receptor variant in this interaction. Mult Scler. 2009; 15: 563–70.DickinsonJLPereraDIvan derMei AFPonsonbyALPolanowskiAMThomsonRJet alPast environmental sun exposure and risk of multiple sclerosis: a role for the Cdx-2 Vitamin D receptor variant in this interaction2009155637010.1177/135245850910245919383647Search in Google Scholar
Partridge JM, Weatherby SJ, Woolmore JA, Highland DJ, Fryer AA, Mann CL, et al. Susceptibility and outcome in MS: associations with polymorphisms in pigmentation-related genes. Neurology. 2004; 62: 2323–5.PartridgeJMWeatherbySJWoolmoreJAHighlandDJFryerAAMannCLet alSusceptibility and outcome in MS: associations with polymorphisms in pigmentation-related genes2004622323510.1212/WNL.62.12.2323Search in Google Scholar
Ozden Kamisli, Ceren Acar, Mert Sozen, Mehmet Tecellioglu, Fatma Ebru Yücel, Dilara Vaizoglu et al. The association between vitamin D receptor polymorphisms and multiple sclerosis in a Turkish population: Multiple Sclerosis and Related Disorders. 2018; 20: 78-81.OzdenKamisliCerenAcarMertSozenMehmetTecelliogluFatmaEbru YücelDilaraVaizogluet al201820788110.1016/j.msard.2018.01.00229331875Search in Google Scholar
Danyal Imani, Bahman Razi, Morteza Motallebnezhad, Ramazan Rezaei. Association between vitamin D receptor(VDR) polymorphisms and the risk of multiple sclerosis (MS): an updated meta-analysis. Imani et al. BMC Neurology. 2019; (19): 339.ImaniDanyalRaziBahmanMotallebnezhadMortezaRezaeiRamazanAssociation between vitamin D receptor(VDR) polymorphisms and the risk of multiple sclerosis (MS): an updated meta-analysis20191933910.1186/s12883-019-1577-y693391231878897Search in Google Scholar
Orton SM, Ramagopalan SV, Para AE, Lincoln MR, Handunnetthi L, Chao MJ et al. Vitamin D metabolic pathway genes and risk of multiple sclerosis in Canadians. J Neurol Sci. 2011; 305(1-2): 116-20.OrtonSMRamagopalanSVParaAELincolnMRHandunnetthiLChaoMJet alVitamin D metabolic pathway genes and risk of multiple sclerosis in Canadians20113051-21162010.1016/j.jns.2011.02.03221440908Search in Google Scholar