Safety of Metamizole Therapy

Metamizole (dipyrone) is a popular non-opioid analgesic and antipyretic drug. In many countries, it has been banned because of a possible association with several adverse drug reactions; in some countries it is available as a prescribed drug. In Poland, dipyrone is sold as an over-the-counter (OTC) drug. The aim of the paper is to determine the types, frequency and the severity of the adverse events caused by dipyrone; based on the latest literature research. Due to the possibility of these events, it is necessary to raise awareness of the principles of safe pharmacotherapy and to draw attention to the potential risk.