<abstract xmlns="http://www.w3.org/1999/xhtml"><p>In recent years, there is a constantly increasing interest in the application of nanoparticles for cancer diagnosis and cancer therapy. In this respect, the most promising nano-objects at present are the gold nanoparticles. A very convenient and powerful property of these objects is their ability to increase their temperature under electro-magnetic irradiation with certain wavelength. In our research we have directed our efforts toward particular nano-objects specifically sensitive to electromagnetic radiation in the near-infrared region (NIR). In order to study the photothermic properties of the solutions of gold nanoparticles in the NIR we constructed a specific electronic setup consisting of a laser system with interchangeable laser diodes with different wavelength NIR light, a thermally-insulated cuvette-holder compartment with temperature measuring probes and a NIR spectrometer to control the stimulated fluorescence emission of the nanoparticles’ solutions. The temperature measurement compartment with the thermal-insulated cuvette holder was designed to maintain the solutions’ temperature at a fixed value right before the moment of laser irradiation. To maintain the measurement setup at a fixed temperature before the irradiation we used a thermal stabilized system based on two Peltier cells with electronic temperature control. The temperatures of the ambient air and the temperature of the cuvette walls were continuously measured in order to make corrections about the temperature dissipation during the irradiation.</p></abstract>

In recent years, there is a constantly increasing interest in the application of nanoparticles for cancer diagnosis and cancer therapy. In this respect, the most promising nano-objects at present are the gold nanoparticles. A very convenient and powerful property of these objects is their ability to increase their temperature under electro-magnetic irradiation with certain wavelength. In our research we have directed our efforts toward particular nano-objects specifically sensitive to electromagnetic radiation in the near-infrared region (NIR). In order to study the photothermic properties of the solutions of gold nanoparticles in the NIR we constructed a specific electronic setup consisting of a laser system with interchangeable laser diodes with different wavelength NIR light, a thermally-insulated cuvette-holder compartment with temperature measuring probes and a NIR spectrometer to control the stimulated fluorescence emission of the nanoparticles’ solutions. The temperature measurement compartment with the thermal-insulated cuvette holder was designed to maintain the solutions’ temperature at a fixed value right before the moment of laser irradiation. To maintain the measurement setup at a fixed temperature before the irradiation we used a thermal stabilized system based on two Peltier cells with electronic temperature control. The temperatures of the ambient air and the temperature of the cuvette walls were continuously measured in order to make corrections about the temperature dissipation during the irradiation.

Experimental setup for light-to-heat NIR conversion measurements of gold nano-particles’ solutions

“Konstantin Preslavsky” University of Shumen

Faculty of Natural Sciences, Department of Physics and Astronomy

Veneto Institute of Oncology IOV – IRCCS

National Institute for Nuclear Physics (INFN)

Acta Scientifica Naturalis

This work is licensed under the Creative Commons Attribution-NonCommercial-NoDerivatives 4.0 License.

In recent years, there is a constantly increasing interest in the application of nanoparticles for cancer diagnosis and cancer therapy. In this respect, the...

Experimental setup for light-to-heat NIR conversion measurements of gold nano-particles’ solutions

Pubblicato online: 07 dic 2018

Pagine: 38 - 47

Ricevuto: 01 set 2018

Accettato: 01 nov 2018

DOI: https://doi.org/10.2478/asn-2018-0019

Parole chiave
Light-to-heat conversion, Gold Nano-Urchins, light-to-heat conversion, Peltier cell, Near Infrared measurements

© 2018 Nikolay Uzunov et al., published by Sciendo

This work is licensed under the Creative Commons Attribution-NonCommercial-NoDerivatives 4.0 License.

Experimental setup for light-to-heat NIR conversion measurements of gold nano-particles’ solutions

Pubblicato online: 07 dic 2018

Pagine: 38 - 47

Ricevuto: 01 set 2018

Accettato: 01 nov 2018

DOI: https://doi.org/10.2478/asn-2018-0019

Parole chiaveLight-to-heat conversion, Gold Nano-Urchins, light-to-heat conversion, Peltier cell, Near Infrared measurements

© 2018 Nikolay Uzunov et al., published by Sciendo

This work is licensed under the Creative Commons Attribution-NonCommercial-NoDerivatives 4.0 License.

Parole chiave
Light-to-heat conversion, Gold Nano-Urchins, light-to-heat conversion, Peltier cell, Near Infrared measurements