<abstract xmlns="http://www.w3.org/1999/xhtml"><p>The aerial parts of T. gallica collected from three different locations (arid, humid and semi-arid) were extracted using ethyl acetate. The crude extracts were subjected to phenolic appraisal and antiproliferative activity using ELISA and xCELLigence assays. The total phenolic and flavonoids were evaluated using appropriate techniques to give a yield of total phenolics ranging between 238.46 and 348.56 mg GAE (Gallic acid equivalent)/g dry weight extract. The flavonoids yield was found to vary from 36.6 to 103.14 mg QE (quercetin equivalent)/g dry weight extract. Moreover, the extracts were tested against rat brain tumor (C6) and human cervix carcinoma (HeLa) cell lines and displayed important differences in activity. These disparities highlighted the effect of climatic factors as quality determinants of secondary metabolites and therefore as a key control of the biological therapeutic effect.</p></abstract>

The aerial parts of T. gallica collected from three different locations (arid, humid and semi-arid) were extracted using ethyl acetate. The crude extracts were subjected to phenolic appraisal and antiproliferative activity using ELISA and xCELLigence assays. The total phenolic and flavonoids were evaluated using appropriate techniques to give a yield of total phenolics ranging between 238.46 and 348.56 mg GAE (Gallic acid equivalent)/g dry weight extract. The flavonoids yield was found to vary from 36.6 to 103.14 mg QE (quercetin equivalent)/g dry weight extract. Moreover, the extracts were tested against rat brain tumor (C6) and human cervix carcinoma (HeLa) cell lines and displayed important differences in activity. These disparities highlighted the effect of climatic factors as quality determinants of secondary metabolites and therefore as a key control of the biological therapeutic effect.

Anti-proliferative activity of ethyl acetate extracts of <italic>Tamarix gallica L.</italic> grown at different climatic conditions in Algeria

Faculty of sciences, department of natural and life sciences

Laboratory of Natural Resources and Management of Sensitive Environments

Laboratory of Biomolecules and Plant Breeding

Life Science and Nature Department, Faculty of Exact Science and Life Science and Nature

Department of Chemistry, Faculty of Science, Uluyazi Campus

Acta Scientifica Naturalis

This work is licensed under the Creative Commons Attribution-NonCommercial-NoDerivatives 4.0 License.

Anti-proliferative activity of ethyl acetate extracts of  grown at different climatic conditions in Algeria

The aerial parts of T. gallica collected from three different locations (arid, humid and semi-arid) were extracted using ethyl acetate. The crude extracts were...

Anti-proliferative activity of ethyl acetate extracts of Tamarix gallica L. grown at different climatic conditions in Algeria

Pubblicato online: 07 dic 2018

Pagine: 23 - 31

Ricevuto: 01 set 2018

Accettato: 01 nov 2018

DOI: https://doi.org/10.2478/asn-2018-0017

Parole chiave
Tamarix gallica, Geographic Origins, ethyl acetate, phenolic, flavonoids, anti-cancer activity

© 2018 Ouroud Fellah et al., published by Sciendo

This work is licensed under the Creative Commons Attribution-NonCommercial-NoDerivatives 4.0 License.

Anti-proliferative activity of ethyl acetate extracts of Tamarix gallica L. grown at different climatic conditions in Algeria

Pubblicato online: 07 dic 2018

Pagine: 23 - 31

Ricevuto: 01 set 2018

Accettato: 01 nov 2018

DOI: https://doi.org/10.2478/asn-2018-0017

Parole chiaveTamarix gallica, Geographic Origins, ethyl acetate, phenolic, flavonoids, anti-cancer activity

© 2018 Ouroud Fellah et al., published by Sciendo

This work is licensed under the Creative Commons Attribution-NonCommercial-NoDerivatives 4.0 License.

Parole chiave
Tamarix gallica, Geographic Origins, ethyl acetate, phenolic, flavonoids, anti-cancer activity