<abstract xmlns="http://www.w3.org/1999/xhtml">

<p>It is well known that vitamin D’s general immunomodulatory actions are helpful in viral infections and that a shortage is linked to a more serious prognosis for Covid-19. In this sistematic review, we examined the existing literature on evidence as to whether there is also link between vitamin D range levels in pediatric population and the outcome of the Covid-19 infection. We looked for studies that measured vitamin D blood concentrations and examined the effects of vitamin D supplementation in young infected patients. Vitamin D may decrease the risk of respiratory infections in a number of ways through its interactions with numerous cells, including by decreasing viral survival and replication, reducing the cytokine storm, raising angiotensin-converting enzyme 2 concentrations (ACE2) while not damaging the endothelial integrity. The incidence or severity of Covid-19 is linked with blood 25-hydroxyvitamin D concentrations, according to many observational studies. However experimental verification is still needed. Given their safety and broad therapeutic window, vitamin D supplements seem to be an effective way for individuals and doctors to prevent or treat Covid-19. Nonetheless, the outcomes of significant vitamin D randomized controlled trials are further needed.</p>
</abstract>

It is well known that vitamin D’s general immunomodulatory actions are helpful in viral infections and that a shortage is linked to a more serious prognosis for Covid-19. In this sistematic review, we examined the existing literature on evidence as to whether there is also link between vitamin D range levels in pediatric population and the outcome of the Covid-19 infection. We looked for studies that measured vitamin D blood concentrations and examined the effects of vitamin D supplementation in young infected patients. Vitamin D may decrease the risk of respiratory infections in a number of ways through its interactions with numerous cells, including by decreasing viral survival and replication, reducing the cytokine storm, raising angiotensin-converting enzyme 2 concentrations (ACE2) while not damaging the endothelial integrity. The incidence or severity of Covid-19 is linked with blood 25-hydroxyvitamin D concentrations, according to many observational studies. However experimental verification is still needed. Given their safety and broad therapeutic window, vitamin D supplements seem to be an effective way for individuals and doctors to prevent or treat Covid-19. Nonetheless, the outcomes of significant vitamin D randomized controlled trials are further needed.

Should Young Covid-19 Patients be Suplemented with Vitamin D?

ARS Medica Tomitana

This work is licensed under the Creative Commons Attribution 4.0 International License.

{"article-title":"Should Young Covid-19 Patients be Suplemented with Vitamin D?"}

It is well known that vitamin D’s general immunomodulatory actions are helpful in viral infections and that a shortage is linked to a more serious prognosis...

Should Young Covid-19 Patients be Suplemented with Vitamin D?

Pubblicato online: 15 mag 2023

Pagine: 73 - 77

DOI: https://doi.org/10.2478/arsm-2022-0017

Parole chiave
25-hydroxyvitamin D, Covid-19, vitamin D

© 2022 Maria Nicolae et al., published by Sciendo

This work is licensed under the Creative Commons Attribution 4.0 International License.

Should Young Covid-19 Patients be Suplemented with Vitamin D?

Pubblicato online: 15 mag 2023

Pagine: 73 - 77

DOI: https://doi.org/10.2478/arsm-2022-0017

Parole chiave25-hydroxyvitamin D, Covid-19, vitamin D

© 2022 Maria Nicolae et al., published by Sciendo

This work is licensed under the Creative Commons Attribution 4.0 International License.

Parole chiave
25-hydroxyvitamin D, Covid-19, vitamin D