This work is licensed under the Creative Commons Attribution 4.0 International License.
Farid H. Chatbots in Digital Marketing. In: Chintalapati & Pandey, eds. Chapter 3: Contemporary Approaches in Digital Marketing and the Role of Machine Intelligence. Hershey, (PA): IGI Global; 2023:46–67.FaridH.Chatbots in Digital Marketing. In: Chintalapati & Pandey, eds. Chapter 3: Contemporary Approaches in Digital Marketing and the Role of Machine Intelligence. Hershey, (PA): IGI Global; 2023:46–67.Search in Google Scholar
Skjuve M, Følstad A, Fostervold KI, Brandtzaeg PB. My chatbot companion-a study of human-chatbot relationships. Int J Hum Comput Stud 2021;149:102601.SkjuveMFølstadAFostervoldKIBrandtzaegPB.My chatbot companion-a study of human-chatbot relationships. Int J Hum Comput Stud2021;149:102601.Search in Google Scholar
Dobbala MK, Lingolu MSS. Conversational ai and chatbots: Enhancing user experience on websites. AJCSIT 2024;7:11.DobbalaMKLingoluMSS.Conversational ai and chatbots: Enhancing user experience on websites. AJCSIT2024;7:11.Search in Google Scholar
Ait Baha T, El Hajji M, Es-Saady Y, Fadili H. The impact of educational chatbot on student learning experience. Educ Inf Technol 2024;29:10153–76.Ait BahaTEl HajjiMEs-SaadyYFadiliH.The impact of educational chatbot on student learning experience. Educ Inf Technol2024;29:10153-76.Search in Google Scholar
Cheng Y, Jiang H. Customer-brand relationship in the era of artificial intelligence: understanding the role of chatbot marketing efforts. J Prod Brand Manag 2022;31:252–64.ChengYJiangH.Customer-brand relationship in the era of artificial intelligence: understanding the role of chatbot marketing efforts. J Prod Brand Manag2022;31:252–64.Search in Google Scholar
García-Méndez S, De Arriba-Perez F, González-Castaño FJ, Regueiro-Janeiro JA, Gil-Castiñeira F. Entertainment chatbot for the digital inclusion of elderly people without abstraction capabilities. IEEE Access 2021;9:75878–91.García-MéndezSDe Arriba-PerezFGonzález-CastañoFJRegueiro-JaneiroJAGil-CastiñeiraF.Entertainment chatbot for the digital inclusion of elderly people without abstraction capabilities. IEEE Access2021;9:75878–91.Search in Google Scholar
Laymouna M, Ma Y, Lessard D, Schuster T, Engler K, Lebouché B. Roles, Users, Benefits, and Limitations of Chatbots in Health Care: Rapid Review. J Med Internet Res 2024;26:e56930.LaymounaMMaYLessardDSchusterTEnglerKLebouchéB.Roles, Users, Benefits, and Limitations of Chatbots in Health Care: Rapid Review. J Med Internet Res2024;26:e56930.Search in Google Scholar
Wang X, Cohen RA. Health Information Technology Use Among Adults: United States, July–December 2022. US Department of Health and Human Services, Centers for Disease Control and Prevention 2023.WangXCohenRA.Health Information Technology Use Among Adults: United States, July–December 2022. US Department of Health and Human Services, Centers for Disease Control and Prevention2023.Search in Google Scholar
Bachl M, Link E, Mangold F, Stier S. Search engine use for health-related purposes: Behavioral data on online health information-seeking in Germany. Health Commun 2024;39:1651–64.BachlMLinkEMangoldFStierS.Search engine use for health-related purposes: Behavioral data on online health information-seeking in Germany. Health Commun2024;39:1651–64.Search in Google Scholar
Li H, Li D, Zhai M, Lin L, Cao Z. Associations Among Online Health Information Seeking Behavior, Online Health Information Perception, and Health Service Utilization: Cross-Sectional Study. J Med Internet Res 2025;27:e66683.LiHLiDZhaiMLinLCaoZ.Associations Among Online Health Information Seeking Behavior, Online Health Information Perception, and Health Service Utilization: Cross-Sectional Study. J Med Internet Res2025;27:e66683.Search in Google Scholar
De Looper M, van Weert JC, Schouten BC, Bolle S, Belgers EH, Eddes EH, et al. The influence of online health information seeking before a consultation on anxiety, satisfaction, and information recall, mediated by patient participation: field study. J J Med Internet Res 2021;23:e23670.De LooperMvan WeertJCSchoutenBCBolleSBelgersEHEddesEHThe influence of online health information seeking before a consultation on anxiety, satisfaction, and information recall, mediated by patient participation: field study. J J Med Internet Res2021;23:e23670.Search in Google Scholar
Bibault J-E, Chaix B, Guillemassé A, Cousin S, Escande A, Perrin M, et al. A chatbot versus physicians to provide information for patients with breast cancer: blind, randomized controlled noninferiority trial. J Med Internet Res 2019;21:e15787.BibaultJ-EChaixBGuillemasséACousinSEscandeAPerrinMA chatbot versus physicians to provide information for patients with breast cancer: blind, randomized controlled noninferiority trial. J Med Internet Res2019;21:e15787.Search in Google Scholar
Topol E. Deep medicine: how artificial intelligence can make healthcare human again. Hachette UK 2019TopolE.Deep medicine: how artificial intelligence can make healthcare human again. Hachette UK2019Search in Google Scholar
Alpaydin MT, Buyuk SK, Bavbek NC. Information on the Internet about clear aligner treatment—an assessment of content, quality, and readability. J Orofac Orthop 2021;83(Suppl 1):1.AlpaydinMTBuyukSKBavbekNC.Information on the Internet about clear aligner treatment—an assessment of content, quality, and readability. J Orofac Orthop2021;83(Suppl 1):1.Search in Google Scholar
Gritti MN, AlTurki H, Farid P, Morgan CT. Progression of an artificial intelligence chatbot (ChatGPT) for pediatric cardiology educational knowledge assessment. Pediatr Cardiol 2024;45:309–13.GrittiMNAlTurkiHFaridPMorganCT.Progression of an artificial intelligence chatbot (ChatGPT) for pediatric cardiology educational knowledge assessment. Pediatr Cardiol2024;45:309–13.Search in Google Scholar
Lam WY, Au SCL. Stroke care in the ChatGPT era: Potential use in early symptom recognition. J Acute Dis 2023;12:129–30.LamWYAuSCL.Stroke care in the ChatGPT era: Potential use in early symptom recognition. J Acute Dis2023;12:129–30.Search in Google Scholar
Kilinç DD, Mansiz D. Examination of the reliability and readability of Chatbot Generative Pretrained Transformer’s (ChatGPT) responses to questions about orthodontics and the evolution of these responses in an updated version. Am J Orthod Dentofacial Orthop 2024;165:546–55.KilinçDDMansizD.Examination of the reliability and readability of Chatbot Generative Pretrained Transformer’s (ChatGPT) responses to questions about orthodontics and the evolution of these responses in an updated version. Am J Orthod Dentofacial Orthop2024;165:546–55.Search in Google Scholar
Daraqel B, Wafaie K, Mohammed H, Cao L, Mheissen S, Liu Y, et al. The performance of artificial intelligence models in generating responses to general orthodontic questions: ChatGPT vs Google Bard. Am J Orthod Dentofacial Orthop 2024;165:652–62.DaraqelBWafaieKMohammedHCaoLMheissenSLiuYThe performance of artificial intelligence models in generating responses to general orthodontic questions: ChatGPT vs Google Bard. Am J Orthod Dentofacial Orthop2024;165:652–62.Search in Google Scholar
Dursun D, Bilici Geçer R. Can artificial intelligence models serve as patient information consultants in orthodontics? BMC Med Inform Decis Mak 2024;24:211.DursunDBilici GeçerR.Can artificial intelligence models serve as patient information consultants in orthodontics?BMC Med Inform Decis Mak2024;24:211.Search in Google Scholar
Hatia A, Doldo T, Parrini S, Chisci E, Cipriani L, Montagna L, et al. Accuracy and completeness of ChatGPT-Generated information on interceptive orthodontics: a Multicenter Collaborative Study. J Clin Med 2024;13:735.HatiaADoldoTParriniSChisciECiprianiLMontagnaLAccuracy and completeness of ChatGPT-Generated information on interceptive orthodontics: a Multicenter Collaborative Study. J Clin Med2024;13:735.Search in Google Scholar
Mavreas D, Athanasiou AE. Factors affecting the duration of orthodontic treatment: A systematic review. Eur J of Orthod 2008;30:386–95.MavreasDAthanasiouAE.Factors affecting the duration of orthodontic treatment: A systematic review. Eur J of Orthod2008;30:386–95.Search in Google Scholar
Grisar K, Luyten J, Preda F, Martin C, Hoppenreijs T, Politis C, et al. Interventions for impacted maxillary canines: A systematic review of the relationship between initial canine position and treatment outcome. Orthod Craniofac Res 2021;24:180–93.GrisarKLuytenJPredaFMartinCHoppenreijsTPolitisCInterventions for impacted maxillary canines: A systematic review of the relationship between initial canine position and treatment outcome. Orthod Craniofac Res2021;24:180–93.Search in Google Scholar
Mancini A, Chirico F, Colella G, Piras F, Colonna V, Marotti P, et al. Evaluating the success rates and effectiveness of surgical and orthodontic interventions for impacted canines: a systematic review of surgical and orthodontic interventions and a case series. BMC Oral Health 2025;25:295.ManciniAChiricoFColellaGPirasFColonnaVMarottiPEvaluating the success rates and effectiveness of surgical and orthodontic interventions for impacted canines: a systematic review of surgical and orthodontic interventions and a case series. BMC Oral Health2025;25:295.Search in Google Scholar
Arslan C, Kahya, K, Cesur E, Cakan DG. An evaluation of orthodontic information quality regarding artificial intelligence (AI) chatbot technologies: A comparison of ChatGPT and google BARD. Australas Orthod J 2024;40:149–57.ArslanCKahyaKCesurECakanDG.An evaluation of orthodontic information quality regarding artificial intelligence (AI) chatbot technologies: A comparison of ChatGPT and google BARD. Australas Orthod J2024;40:149–57.Search in Google Scholar
Charnock D, Shepperd S, Needham G, Gann R. DISCERN: an instrument for judging the quality of written consumer health information on treatment choices. J Epidemiol Community Health 1999;53:105–11.CharnockDShepperdSNeedhamGGannR.DISCERN: an instrument for judging the quality of written consumer health information on treatment choices. J Epidemiol Community Health1999;53:105–11.Search in Google Scholar
Onder C, Koc G, Gokbulut P, Taskaldiran I, Kuskonmaz S. Evaluation of the reliability and readability of ChatGPT-4 responses regarding hypothyroidism during pregnancy. Sci Rep 2024;14:243.OnderCKocGGokbulutPTaskaldiranIKuskonmazS.Evaluation of the reliability and readability of ChatGPT-4 responses regarding hypothyroidism during pregnancy. Sci Rep2024;14:243.Search in Google Scholar
Kincaid JP, Fishburne Jr RP, Rogers RL, Chissom BS. Derivation of new readability formulas (automated readability index, fog count and flesch reading ease formula) for navy enlisted personnel (Research Branch Report 8-75). Naval Technical Training Command 1975.KincaidJPFishburneRPJrRogersRLChissomBS.Derivation of new readability formulas (automated readability index, fog count and flesch reading ease formula) for navy enlisted personnel (Research Branch Report 8-75). Naval Technical Training Command1975.Search in Google Scholar
Chu JT, Wang MP, Shen C, Viswanath K, Lam TH, Chan SSC. How, when and why people seek health information online: qualitative study in Hong Kong. Interact J Med Res 2017;6:e7000.ChuJTWangMPShenCViswanathKLamTHChanSSC.How, when and why people seek health information online: qualitative study in Hong Kong. Interact J Med Res2017;6:e7000.Search in Google Scholar
Bachl M, Link E, Mangold F, Stier S. Search engine use for health-related purposes: Behavioral data on online health information-seeking in Germany. Health Commun 2024;39:1–14.BachlMLinkEMangoldFStierS.Search engine use for health-related purposes: Behavioral data on online health information-seeking in Germany. Health Commun2024;39:1–14.Search in Google Scholar
Davis RJ, Ayo-Ajibola O, Lin ME, Swanson MS, Chambers TN, Kwon DI, et al. Evaluation of oropharyngeal cancer information from revolutionary artificial intelligence chatbot. The Laryngoscope 2024;134:2252–7.DavisRJAyo-AjibolaOLinMESwansonMSChambersTNKwonDIEvaluation of oropharyngeal cancer information from revolutionary artificial intelligence chatbot. The Laryngoscope2024;134:2252–7.Search in Google Scholar
Balel Y. Can ChatGPT be used in oral and maxillofacial surgery? J Stomatol Oral Maxillofac Surg 2023;124:101471.BalelY.Can ChatGPT be used in oral and maxillofacial surgery?J Stomatol Oral Maxillofac Surg2023;124:101471.Search in Google Scholar
Tanaka OM, Gasparello GG, Hartmann GC, Casagrande FA, Pithon MM. Assessing the reliability of ChatGPT: a content analysis of self-generated and self-answered questions on clear aligners, TADs and digital imaging. Dental Press J Orthod 2023;28: e2323183.TanakaOMGasparelloGGHartmannGCCasagrandeFAPithonMM.Assessing the reliability of ChatGPT: a content analysis of self-generated and self-answered questions on clear aligners, TADs and digital imaging. Dental Press J Orthod2023;28: e2323183.Search in Google Scholar
Perez-Pino A, Yadav S, Upadhyay M, Cardarelli L, Tadinada A. The accuracy of artificial intelligence–based virtual assistants in responding to routinely asked questions about orthodontics. Angle Orthod 2023;93:427–32.Perez-PinoAYadavSUpadhyayMCardarelliLTadinadaA.The accuracy of artificial intelligence–based virtual assistants in responding to routinely asked questions about orthodontics. Angle Orthod2023;93:427–32.Search in Google Scholar
Tanaka OM, Weissheimer A, Pithon MM, Gasparello GG, Araújo EA. Focus on leveling the hidden: managing impacted maxillary canines. Dental Press J Orthod 2024;29:e24spe5.TanakaOMWeissheimerAPithonMMGasparelloGGAraújoEA.Focus on leveling the hidden: managing impacted maxillary canines. Dental Press J Orthod2024;29:e24spe5.Search in Google Scholar
Smutny P, Bojko M. Comparative Analysis of Chatbots Using Large Language Models for Web Development Tasks. Appl Sci 2024;14:10048.SmutnyPBojkoM.Comparative Analysis of Chatbots Using Large Language Models for Web Development Tasks. Appl Sci2024;14:10048.Search in Google Scholar
Vaishya R, Misra A, Vaish A. ChatGPT: Is this version good for healthcare and research? Diabetes Metab Syndr 2023;17: 102744.VaishyaRMisraAVaishA.ChatGPT: Is this version good for healthcare and research?Diabetes Metab Syndr2023;17: 102744.Search in Google Scholar
Aziz AAA, Abdelrahman HH, Hassan MG. The use of ChatGPT and Google Gemini in responding to orthognathic surgery-related questions: A comparative study. J World Fed Orthod 2025;14: 20–6.AzizAAAAbdelrahmanHHHassanMG.The use of ChatGPT and Google Gemini in responding to orthognathic surgery-related questions: A comparative study. J World Fed Orthod2025;14: 20–6.Search in Google Scholar
Carifio J, Perla RJ. A critique of the theoretical and empirical literature of the use of diagrams, graphs, and other visual aids in the learning of scientific-technical content from expository texts and instruction. Interchange 2009;40:403–36.CarifioJPerlaRJ.A critique of the theoretical and empirical literature of the use of diagrams, graphs, and other visual aids in the learning of scientific-technical content from expository texts and instruction. Interchange2009;40:403–36.Search in Google Scholar
Alhazmi K. The Effect of Multimedia on Vocabulary Learning and Retention. World J Engl Lang 2024;14:390.AlhazmiK.The Effect of Multimedia on Vocabulary Learning and Retention. World J Engl Lang2024;14:390.Search in Google Scholar
Taymour N, Fouda SM, Abdelrahaman HH, Hassan MG. Performance of the ChatGPT-3.5, ChatGPT-4, and Google Gemini large language models in responding to dental implantology inquiries. J Prosthet Dent 2025. [Epub ahead of print]TaymourNFoudaSMAbdelrahamanHHHassanMG.Performance of the ChatGPT-3.5, ChatGPT-4, and Google Gemini large language models in responding to dental implantology inquiries. J Prosthet Dent2025. [Epub ahead of print]Search in Google Scholar
Johnson AJ, Singh TK, Gupta A, Sankar H, Gill I, Shalini M, et al. Evaluation of validity and reliability of AI Chatbots as public sources of information on dental trauma. Dent Traumatol 2024;41 41:187–193.JohnsonAJSinghTKGuptaASankarHGillIShaliniMEvaluation of validity and reliability of AI Chatbots as public sources of information on dental trauma. Dent Traumatol2024;41 41:187–193.Search in Google Scholar
Mustuloğlu Ş, Deniz BP. Evaluation of Chatbots in the Emergency Management of Avulsion Injuries. Dent Traumatol 2025:1–8.MustuloğluŞDenizBP.Evaluation of Chatbots in the Emergency Management of Avulsion Injuries. Dent Traumatol2025:1–8.Search in Google Scholar
Sami MA, Samad MA, Parekh K, Suthar PP. Comparative accuracy of ChatGPT 4.0 and Google Gemini in answering pediatric radiology text-based questions. Cureus 2024;16: e70897.SamiMASamadMAParekhKSutharPP.Comparative accuracy of ChatGPT 4.0 and Google Gemini in answering pediatric radiology text-based questions. Cureus2024;16: e70897.Search in Google Scholar
Strzalkowski P, Strzalkowska A, Chhablani J, Pfau K, Errera MH, Roth M, et al. Evaluation of the accuracy and readability of ChatGPT-4 and Google Gemini in providing information on retinal detachment: A multicenter expert comparative study. Int J Retina Vitreous 2024;10:61.StrzalkowskiPStrzalkowskaAChhablaniJPfauKErreraMHRothMEvaluation of the accuracy and readability of ChatGPT-4 and Google Gemini in providing information on retinal detachment: A multicenter expert comparative study. Int J Retina Vitreous2024;10:61.Search in Google Scholar
Mishra V, Dexter JP. Comparison of readability of official public health information about COVID-19 on websites of international agencies and the governments of 15 countries. JAMA Netw Open 2020;3:e2018033–e2018033.MishraVDexterJP.Comparison of readability of official public health information about COVID-19 on websites of international agencies and the governments of 15 countries. JAMA Netw Open2020;3:e2018033–e2018033.Search in Google Scholar
Abou-Abdallah M, Dar T, Mahmudzade Y, Michaels J, Talwar R, Tornari C. The quality and readability of patient information provided by ChatGPT: can AI reliably explain common ENT operations? Eur Arch Otorhinolaryngol 2024;281:6147–6153.Abou-AbdallahMDarTMahmudzadeYMichaelsJTalwarRTornariC.The quality and readability of patient information provided by ChatGPT: can AI reliably explain common ENT operations?Eur Arch Otorhinolaryngol2024;281:6147–6153.Search in Google Scholar
Yurdakurban E, Topsakal KG, Duran GS. A comparative analysis of AI-based chatbots: Assessing data quality in orthognathic surgery related patient information. J Stomol Oral Maxillofac Surg 2024;125:101757.YurdakurbanETopsakalKGDuranGS.A comparative analysis of AI-based chatbots: Assessing data quality in orthognathic surgery related patient information. J Stomol Oral Maxillofac Surg2024;125:101757.Search in Google Scholar
Mohammad-Rahimi H, Ourang SA, Pourhoseingholi MA, Dianat O, Dummer PMH, Nosrat A. Validity and reliability of artificial intelligence chatbots as public sources of information on endodontics. Int Endod J 2024;57:305–14.Mohammad-RahimiHOurangSAPourhoseingholiMADianatODummerPMHNosratA.Validity and reliability of artificial intelligence chatbots as public sources of information on endodontics. Int Endod J2024;57:305–14.Search in Google Scholar
Lima NGM, Costa L, Santos PB. ChatGPT in orthodontics: Limitations and possibilities. Australas Orthod J 2024;40:19–21.LimaNGMCostaLSantosPB.ChatGPT in orthodontics: Limitations and possibilities. Australas Orthod J2024;40:19–21.Search in Google Scholar
Andrikyan W, Sametinger SM, Kosfeld F, Jung-Poppe L, Fromm MF, Maas R, et al. Artificial intelligence-powered chatbots in search engines: a cross-sectional study on the quality and risks of drug information for patients. BMJ Qual Saf 2025;34:100–9.AndrikyanWSametingerSMKosfeldFJung-PoppeLFrommMFMaasRArtificial intelligence-powered chatbots in search engines: a cross-sectional study on the quality and risks of drug information for patients. BMJ Qual Saf2025;34:100–9.Search in Google Scholar
Zada T, Tam N, Barnard F, Van Sittert M, Bhat V, Rambhatla S. Medical Misinformation in AI-Assisted Self-Diagnosis: Development of a Method (EvalPrompt) for Analyzing Large Language Models. JMIR Form Res 2025;9:e66207.ZadaTTamNBarnardFVan SittertMBhatVRambhatlaS.Medical Misinformation in AI-Assisted Self-Diagnosis: Development of a Method (EvalPrompt) for Analyzing Large Language Models. JMIR Form Res2025;9:e66207.Search in Google Scholar
